Dermatological Disorders

C-Reative Protein Levels and Spontaneous Urticaria: Is There a Link?

December 06, 2017

The researchers found that one-third of patients exhibiting CSU had elevated levels of CRP.

Taltz Approved for the Treatment of Active Psoriatic Arthritis

By December 04, 2017

Taltz may be administered alone or in combination with a conventional disease-modifying antirheumatic drug, such as methotrexate.

FDA Expands Use of DESCRIBE PFD Patch for Laser Treatment of Tattoos

By December 04, 2017

The Patch, which is placed over tattoos prior to removal with a laser, allows physicians to treat tattoos more efficiently by enabling rapid multiple laser passes in a single treatment session.

Phase 3 Results Show Further Efficacy of Novel Plaque Psoriasis Tx

By December 04, 2017

At 16 weeks, 73% of risankizumab patients achieved PSAI 90 vs. 2% of the placebo patients and sPGA 0/1 was reached by 84% of riskanizumab patients vs. 7% of placebo patients (P<0.001).

Impoyz Cream Approved for Moderate to Severe Plaque Psoriasis

By December 01, 2017

Impoyz Cream will be available as a 0.025% cream in 60g and 112g tubes.

Psoriasis Treatments

December 01, 2017

Systemic therapy treatment chart for psoriasis patients generally reserved for those with chronic plaque psoriasis without psoriatic arthritis who are candidates for systemic treatment when UV therapy is not available.

Survey Shows Atopic Dermatitis Often Inadequately Controlled

December 01, 2017

The control rate increased with current AD severity and was 53.4% among patients receiving immunosuppressants and 83.4% among patients receiving systemic corticosteroids.

Hidradenitis Suppurativa: Pharmacological and Surgical Txs Reviewed

By November 29, 2017

The authors reported significant disability and comorbidities among patients with HS, including obesity, metabolic syndrome, diabetes, and arthritis.

Perrigo Approved for Generic Mycolog II Cream

By November 28, 2017

Triamcinolone acetonide is mainly effective because of its anti-inflammatory, antipruritic and vasoconstrictive actions.

Sunscreen Ingredient Linked to Dermatological and Environmental Toxicity

November 22, 2017

Increased adverse reactions may be result of closed loop involving ingesting fish, washing ingredient off

Body Surface Area Affected by Psoriasis May Be Linked to T2DM Risk

By November 20, 2017

To determine the risk of T2DM, researchers compared adults with psoriasis (n=8124), grouping them by affected BSA, to those without psoriasis (n=76,599); patients were followed for ~4 years.

Impact of Psoriasis Treatments on Depressive Symptoms Examined

By November 20, 2017

Psoriasis patients may be at increased risk for depression and suicidality.

Review Investigates Efficacy of Guselkumab for Plaque Psoriasis

By November 17, 2017

In the other Phase 3 trial, transitioning to guselkumab treatment was more effective than continued ustekinumab use in reducing IGA scores in those minimally responsive to ustekinmab.

Physician, Patient Survey Reveals Most Important Attributes of Psoriasis Tx

By November 17, 2017

The study quantifies the importance of clinical attributes of psoriasis therapies that dermatologists and psoriasis patients consider when choosing treatments.

FDA: Serious Injuries With Injectable Silicone Used for Body Contouring

By November 14, 2017

Silicone injections for body contouring are often performed by unlicensed and non-medical practitioners in non-clinical settings such as residential homes or hotels.

Combo Tx Shows Promise for Improving Acne Scars

November 09, 2017

The researchers found that for the 52 patients completing the trial, there was a greater decrease in the mean ECCA score in the combination treatment group compared with the microneedling-only group.

Some Prescription-Strength Meds May Be Easily Acquired Over-the-Counter

November 03, 2017

"Dermatologists and primary care physicians should be cognizant of any over-the-counter product that their patients are using," the authors of a JAMA report write.

FDA Accepts NDA for Topical Combination Treatment for Plaque Psoriasis

By November 02, 2017

The Prescription Drug User Fee Act (PDUFA) action date is June 18, 2018.

Lice and Scabies Treatments

October 27, 2017

Lice and scabies treatment chart, including pediculicides, scabicides, and lice and nit removal aids.

Rare Disorder Causes Patient to Spontaneously 'Sweat Blood'

By October 24, 2017

During the patient's admission, a bleeding episode occurred which resulted in blood-stained fluid on her face.

Proton Pump Inhibitor Use Linked to Two Distinct Dermatological Reactions

By October 18, 2017

The case involved a 32-year-old male who was prescribed pantoprazole after initially presenting with dyspepsia-like symptoms.

Alcohol May Contribute to Premature Mortality in Psoriasis Patients

By October 17, 2017

The researchers compared an cohort of patients with psoriasis (≥18 years of age) drawn from several databases to 20 patients without psoriasis who were matched by age, sex, and general practice (n=55,537 and 854,314 respectively).

Safety of Systemic Medications Investigated in Pediatric Psoriasis

By October 17, 2017

Methotrexate was the most commonly used agent (270 patients [69.2%]), followed by biologic agents, primarily etanercept (106 [27.2%]), acitretin (57 [14.6%]), cyclosporine (30 [7.7%]), and fumaric acid esters by (19 [4.9%]). Seventy-three patients (18.7%) used ≥1 medication.

Stelara Approved to Treat Adolescent Patients With Plaque Psoriasis

By October 16, 2017

The expanded approval was supported by data from a Phase 3 study that evaluated the safety and efficacy of subcutaneous Stelara in adolescents aged ≥12 years.

Investigational Hyperhidrosis Therapy Found to Be Safe, Effective

By October 13, 2017

Daily treatment with glycopyrronium tosylate in the Phase 3, open-label ARIDO trial was generally well-tolerated during 44 weeks of treatment.

When Is Systemic Treatment Appropriate for Atopic Dermatitis?

October 13, 2017

The authors recommend a systematic and holistic approach to assess patients with severe signs and symptoms of AD and impact on quality of life before systemic therapy.

Has Mass Media Criteria for What Constitutes Beauty Evolved?

October 12, 2017

In 1990, Fitzpatrick skin types I to III represented 88% of the celebrities on the list and Fitzpatrick skin types IV to VI represented 12%; in contrast, in 2017, Fitzpatrick skin types I to III and IV to VI represented 70.4 and 29.6%, respectively

Crisaborole Safe for Long-Term Treatment of Atopic Dermatitis

October 11, 2017

Researchers assessed the long-term safety results from a multicenter, open-label, 48-week safety study of 517 patients ≥2 years of age with mild to moderate AD who continued crisaborole treatment after completing a 28-day phase 3 pivotal study.

Botox Approved for Improving Moderate to Severe Forehead Lines

By October 11, 2017

Botox Cosmetic is already approved for the temporary improvement of crow's feet lines and frown lines between the eyebrows in adults.

Test Helps Clinicians Select Appropriate Tx for Suspected Wound Infections

By October 05, 2017

Using a simple swab from the infection site, DxWound uses a special transport buffer that preserves the wound microbiome during transit.