Dermatological Disorders

Topical Coal Tar: An Effective Alternative for Psoriasis?

August 17, 2017

Coal tar is one of the oldest psoriasis treatments though its exact mechanism is not known.

Economic Evidence Lacking for Vitiligo Treatment

August 17, 2017

Research reveals no evidence to support or refute value for money afforded by vitiligo treatments.

EpiCeram Now Available as Quad Pack Airless Pumps

By August 16, 2017

EpiCeram contains a balanced ratio of ceramides, free fatty acids, and cholesterol, which are essential lipids for total skin barrier repair; they mimic the lipid concentration found in the skin.

Psoriatic Arthritis Treatment Trends Investigated

By August 15, 2017

Researchers used claims data between 2004-2015 from a large commercial database to identify patients with psoriatic arthritis who were initiated on DMARDs.

Nutraseb Available for the Management of Seborrheic Dermatitis

By August 15, 2017

A clinical trial of Promiseb (NCT01214434) found the cream to be safe and significantly efficacious in reducing scaling from baseline to end of treatment when compared with a bland emollient (58%; SD: 62 vs. 90%; SD: 22).

Anti-Aging Tx Interest Similar Across Patient Gender, Age and Income

August 14, 2017

The researchers found that 53% of the general dermatology patient population has used an anti-aging treatment in the past, and 66% reporting interest in future use.

Intradermal Hyaluronic Acid Efficacy Examined for Facial Pores

August 11, 2017

The researchers observed a significant difference in the appearance of enlarged facial pores (P<0.01) before and after treatment. There were no reports of infection, nodules, or pigmentation at the injection sites.

Which Medications Are Prescribed Most Often for Atopic Dermatitis?

By August 10, 2017

Male patients exhibited the highest rates of oral steroid prescriptions.

Does Early Probiotic Supplementation Reduce Eczema, Asthma Development?

August 08, 2017

The researchers found that the estimated cumulative incidence of eczema was 30.9 and 28.7% in the control and LGG arms at 2 years of age, respectively.

Preventive Treatments for Recurrent Cellulitis Investigated

August 07, 2017

"Larger, high-quality studies are warranted, including long-term follow-up and other prophylactic measures," the authors write.

Low-Dose Naltrexone Effective for Severe Genetic Blistering Disease

By August 03, 2017

Current treatments for Hailey-Hailey disease, a severe genetic blistering disease of intertriginous skin, have led to varied clinical outcomes with potentially severe side effects.

House Dust Mites May Induce lgE Sensitization to Antigens for Some

July 28, 2017

Researchers used IgE immunoblotting to analyze plasma samples from 179 atopic dermatitis patients for IgE-reactivity to a panel of micro-arrayed house dust mites allergen molecules.

First Interchangeability Study Initiated for Adalimumab Biosimilar

By July 27, 2017

Researchers will compare the pharmacokinetics and clinical outcomes between patients continuously receiving Humira vs. repeatedly switching between Humira and BI 695501.

Biosimilar Renflexis Now Available

July 24, 2017

Infliximab products work by neutralizing the biological activity of TNF-alpha by binding with high affinity to the soluble and transmembrane forms of TNF-alpha and inhibiting the binding of TNF-alpha with its receptors.

Octagam 10% Gains Orphan Drug Status for Rare Muscle, Skin Disorder

July 17, 2017

Octagam 10% is currently approved to treat chronic immune thrombocytopenic purpura (ITP) in adult patients. It is supplied as 2g, 5g, 10g, or 20g single-use bottles.

Tremfya Approved for Moderate to Severe Plaque Psoriasis

By July 13, 2017

In the NAVIGATE study, 31% of patients treated with Tremfya were considered cleared or almost cleared vs. 14% of patients treated with Stelara (ustekinumab; Janssen Biotech) at Week 28.

FDA Clears At-Home Light Therapy Device for Psoriasis

By July 13, 2017

A clinical trial (Pfaff S et al. 2015) of 47 individuals with mild psoriasis found significant improvement in change from baseline of Local Psoriasis Severity Index in patients receiving UV-free blue light home treatment.

Aquaphor Baby Fast Relief Paste Available for Diaper Rash

By July 12, 2017

Aquaphor Baby Fast Relief Paste is available in 3.5oz (99g) tubes.

Pesticide-Free Lice Treatment Gets FDA Clearance

By July 11, 2017

Resultz is an odorless treatment that kills and removes head lice with a 5 minute application time; this is the shortest time frame associated with currently available lice products.

High-Dose Vitamin D May Benefit Skin After Sunburn

By July 07, 2017

The study found that subjects who took the highest doses of vitamin D had long-term benefits, including reduced skin inflammation 48 hours after the burn.

Topical Steroid Potencies

July 07, 2017

Topical steroid classification chart sorted by potency.

Cutaneous Procedures During Isotretinoin Rx May Be OK

June 29, 2017

The researchers found that for patients currently receiving or having recently completed isotretinoin therapy, there was insufficient evidence to support delaying manual dermabrasion, superficial chemical peels, cutaneous surgery, laser hair removal, and fractional ablative and nonablative laser procedures.

Hidradenitis Suppurativa Severity Scoring System Created

June 27, 2017

The number of nodules, abscesses, and draining tunnels were used to calculate the resulting International HS Severity Scoring System (IHS4) score.

Adverse Events Related to Cosmetics, Personal Care Products Underreported

June 27, 2017

Complaints more than doubled between 2015 and 2016, rising from 706 to 1,591 reported adverse events.

Acne Drug May Negatively Impact Tattoo Healing

June 22, 2017

The authors note that the tattooing was uneventful, but the patient presented with impaired tattoo healing. There was no infection, and with use of a proper moisturizer the tattoo eventually healed.

Tofacitinib Assessed for Efficacy in Nail Psoriasis

June 20, 2017

The researchers found that significantly more patients receiving tofacitinib 5mg and tofacitinib 10mg versus placebo achieved a ≥50% reduction in the Nail Psoriasis Severity Index (NAPSI) score from baseline (NAPSI50)

Vitamin B12 Therapy Linked to Acneform Eruptions

June 19, 2017

"A careful pharmacologic history is therefore necessary in all patients with acneiform eruptions," the authors write.

FDA Expands Dysport Use for Lower Limb Spasticity in Adults

By June 16, 2017

The FDA approval was based on data from a Phase 3, multi-center, prospective, double-blind, randomized, placebo-controlled study in 381 adults treated with Dysport 1000 Units, Dysport 1500 Units or placebo after a stroke or traumatic brain injury.

Sleep Disorder Treatment Linked to Serious Skin Side Effect

By June 12, 2017

Serious rash, including SJS, is a reported adverse event in the prescribing information for both modafinil and armodafinil.

Tegaderm CHG IV Securement Dressing Reduces Catheter-Related Infections

By June 06, 2017

In the clinical trial, upon catheter removal, there were decreases noted in catheter colonization and skin colonization rates.