Dermatological Disorders

Proton Pump Inhibitor Use Linked to Two Distinct Dermatological Reactions

By October 18, 2017

The case involved a 32-year-old male who was prescribed pantoprazole after initially presenting with dyspepsia-like symptoms.

Alcohol May Contribute to Premature Mortality in Psoriasis Patients

By October 17, 2017

The researchers compared an cohort of patients with psoriasis (≥18 years of age) drawn from several databases to 20 patients without psoriasis who were matched by age, sex, and general practice (n=55,537 and 854,314 respectively).

Safety of Systemic Medications Investigated in Pediatric Psoriasis

By October 17, 2017

Methotrexate was the most commonly used agent (270 patients [69.2%]), followed by biologic agents, primarily etanercept (106 [27.2%]), acitretin (57 [14.6%]), cyclosporine (30 [7.7%]), and fumaric acid esters by (19 [4.9%]). Seventy-three patients (18.7%) used ≥1 medication.

Stelara Approved to Treat Adolescent Patients With Plaque Psoriasis

By October 16, 2017

The expanded approval was supported by data from a Phase 3 study that evaluated the safety and efficacy of subcutaneous Stelara in adolescents aged ≥12 years.

Investigational Hyperhidrosis Therapy Found to Be Safe, Effective

By October 13, 2017

Daily treatment with glycopyrronium tosylate in the Phase 3, open-label ARIDO trial was generally well-tolerated during 44 weeks of treatment.

When Is Systemic Treatment Appropriate for Atopic Dermatitis?

October 13, 2017

The authors recommend a systematic and holistic approach to assess patients with severe signs and symptoms of AD and impact on quality of life before systemic therapy.

Has Mass Media Criteria for What Constitutes Beauty Evolved?

October 12, 2017

In 1990, Fitzpatrick skin types I to III represented 88% of the celebrities on the list and Fitzpatrick skin types IV to VI represented 12%; in contrast, in 2017, Fitzpatrick skin types I to III and IV to VI represented 70.4 and 29.6%, respectively

Crisaborole Safe for Long-Term Treatment of Atopic Dermatitis

October 11, 2017

Researchers assessed the long-term safety results from a multicenter, open-label, 48-week safety study of 517 patients ≥2 years of age with mild to moderate AD who continued crisaborole treatment after completing a 28-day phase 3 pivotal study.

Botox Approved for Improving Moderate to Severe Forehead Lines

By October 11, 2017

Botox Cosmetic is already approved for the temporary improvement of crow's feet lines and frown lines between the eyebrows in adults.

Test Helps Clinicians Select Appropriate Tx for Suspected Wound Infections

By October 05, 2017

Using a simple swab from the infection site, DxWound uses a special transport buffer that preserves the wound microbiome during transit.

Case: Tattoo Ink-Induced Lymphadenopathy Misdiagnosed as Cancer

October 04, 2017

Case report describes patient with multiple enlarged lymph nodes seen on PET-CT years after tattoo

Secukinumab Efficacy Evaluated in Patients with Scalp Psoriasis

September 29, 2017

Over half of patients have 90 percent improvement on Psoriasis Scalp Severity Index score

International Eczema Council Reach Consensus on Corticosteroid Use

September 26, 2017

In specific circumstances, systemic corticosteroids can be used rarely for severe atopic dermatitis, such as lack of other treatment options, as a bridge to other systemic therapies or phototherapy, during acute flares that need immediate relief, in anticipation of a major life event, or in the most severe cases.

Tuberculosis Vaccine May Carry Dermatological Benefits for Newborns

September 25, 2017

There was a significant difference in the effect of neonatal BCG vaccination between children with atopic predisposition and children without atopic predisposition.

Hair Regrowth in Alopecia Patients After Fecal Transplant for Recurrent CDI

By September 22, 2017

These 2 cases suggests that fecal transplants can have a profound immunological response not only limited to intestinal effects, say the authros.

Oral vs. Topical Isotretinoin in Clearing Wart Lesions

September 22, 2017

For those treated with topical treatment, 5 of 13 patients (38%) had complete remission and 6 (46%) had partial remission.

Dupixent Improves Disease Severity, Skin Clearing in Atopic Dermatitis

By September 20, 2017

The data indicated 59% of patients given Dupixent weekly with topical corticosteroids and 63% of patients given Dupixent every 2 weeks with topical corticosteroids achieved EASI-75 vs. 30% of patients given placebo with topical corticosteroids (P<0.0001).

Tremfya Sustains Long-Term Skin Clearance in Plaque Psoriasis

By September 18, 2017

Patients who were crossed over to Tremfya from Humira showed substantial improvement in PSSD scores from Week 48 to Week 100.

AAP Publish First Guidance on Tattooing, Piercing for Adolescents

By September 18, 2017

These can occur from contamination of the inks or diluents used for tattooing.

Cemiplimab Gains Breakthrough Tx Designation for Advanced Skin Cancer

By September 08, 2017

A Phase 2, single-arm, open-label clinical trial, EMPOWER-CSCC 1, is now enrolling patients with metastatic CSCC and locally advanced and unresectable CSCC.

FDA: Do Not Use These Alcohol Pads, Antiseptic Towelettes

By September 05, 2017

These products may not be sterile and may have other quality issues.

Cases Detail Leukomelanoderma Following Topical Skin Cream Use

August 23, 2017

Two cases documented in patients taking hydroquinone at a concentration of 7 to 10 percent

Topical Coal Tar: An Effective Alternative for Psoriasis?

August 17, 2017

Coal tar is one of the oldest psoriasis treatments though its exact mechanism is not known.

Economic Evidence Lacking for Vitiligo Treatment

August 17, 2017

Research reveals no evidence to support or refute value for money afforded by vitiligo treatments.

EpiCeram Now Available as Quad Pack Airless Pumps

By August 16, 2017

EpiCeram contains a balanced ratio of ceramides, free fatty acids, and cholesterol, which are essential lipids for total skin barrier repair; they mimic the lipid concentration found in the skin.

Psoriatic Arthritis Treatment Trends Investigated

By August 15, 2017

Researchers used claims data between 2004-2015 from a large commercial database to identify patients with psoriatic arthritis who were initiated on DMARDs.

Nutraseb Available for the Management of Seborrheic Dermatitis

By August 15, 2017

A clinical trial of Promiseb (NCT01214434) found the cream to be safe and significantly efficacious in reducing scaling from baseline to end of treatment when compared with a bland emollient (58%; SD: 62 vs. 90%; SD: 22).

Anti-Aging Tx Interest Similar Across Patient Gender, Age and Income

August 14, 2017

The researchers found that 53% of the general dermatology patient population has used an anti-aging treatment in the past, and 66% reporting interest in future use.

Intradermal Hyaluronic Acid Efficacy Examined for Facial Pores

August 11, 2017

The researchers observed a significant difference in the appearance of enlarged facial pores (P<0.01) before and after treatment. There were no reports of infection, nodules, or pigmentation at the injection sites.

Which Medications Are Prescribed Most Often for Atopic Dermatitis?

By August 10, 2017

Male patients exhibited the highest rates of oral steroid prescriptions.