Otrexup Results Published for Rhuematoid Arthritis

Antares Pharma announced the publication of results from its crossover study comparing the relative bioavailability, safety, and tolerability of Otrexup (methotrexate) to oral methotrexate (MTX) in adults with rheumatoid arthritis in the Annals of the Rheumatic Diseases.

Phototherapy for Psoriasis: Understanding UV Therapy

Understanding the treatment options and related side effects of UV therapy can guide the right therapeutic choice for patients with psoriasis.

Emergency Burn Gel to Return to Retail Shelves

Quest Products has announced that it will now distribute Alocane Emergency Burn Gel (Lidocaine HCl 4%), a topical gel for pain and itch relief.

New Fast-Acting Antifungal Cream Launched

Valeant announced that Luzu (luliconazole) Cream is now available.

Sentinel-node Biopsy Succeeds in Early Melanoma Spread Detection

Research on a technique for detecting the earliest spread of melanoma has confirmed that the procedure significantly prolongs patients' survival rates compared with traditional watch-and-wait techniques.

Mederma PM Intensive Overnight Scar Cream Launched

Merz Pharmaceuticals announced the launch of Mederma PM Intensive Overnight Scar Cream (dimethicone 2%), a new cream designed to work at night.

Guselkumab Shows Improvement in Plaque Psoriasis

Janssen R&D announced results from X-PLORE, a Phase 2b study of guselkumab (CNTO 1959) in patients with moderate to severe plaque psoriasis.

Otezla Shows Improvement in Plaque Psoriasis Studies

Celgene announced the release of new research findings on Otezla (apremilast), a selective inhibitor of phosphodiesterase 4 (PDE4), from the ESTEEM 1 and 2 Phase 3 studies in patients with moderate to severe plaque psoriasis.

Xeljanz Demonstrates Efficacy in Chronic Plaque Psoriasis

Pfizer announced results from OPT Compare (A3921080), a Phase 3 study of Xeljanz (tofacitinib) for the treatment of adults with moderate-to-severe chronic plaque psoriasis.

Positive Results Announced for Rosacea Treatment

Galderma announced results from two Phase 3 trials of ivermectin 1%, an investigational drug being evaluated for the treatment of papulopusular rosacea.

Infantile Hemangioma Treatment Approved

Pierre Fabre Dermatologie has received FDA marketing approval of Hemangeol (propranolol HCl) oral solution for the treatment of proliferating infantile hemangioma requiring systemic therapy.

Positive Retrospective Analysis Results for Talimogene for Melanoma

Amgen announced results from a pre-specified retrospective analysis of patients with metastatic melanoma that showed talimogene reduced the size of injected tumors and non-injected metastasized tumors.

Resistant Strain of Head Lice Prevalent in North America

Widespread use of pyrethrins- or pyrethroid-based products appears to have resulted in selection pressure for a highly-resistant strain of human head lice in North America.

Nivolumab May Improve Survival in Advanced Melanoma

For patients with advanced melanoma, nivolumab may improve overall survival and has an acceptable long-term safety profile.

Indoor Tanning Common Among High School Students

Indoor tanning is common among high school students and is linked to engaging in other risky behaviors.

Excessive Tanning Could Reflect Psychiatric Distress

Excessive tanning may indicate the presence of psychiatric distress.

High-Dose Vitamin Beneficial in Chronic Urticaria

Adjuvant high-dose vitamin D3 is beneficial for patients with chronic urticaria.

New Strength of Minocin Caps Available

Onset Dermatologics announced the launch of Minocin (minocycline HCl) 75mg pellet-filled capsules, a new dosage strength for Minocin.

More Older Men Have Skin Exams After Watching Educational Video

Older men are more likely to have a whole-body skin exam done by their physician if they watch a video on skin self-examination and skin awareness.

Teledermatology Is Reliable for Initial Triage Consultations

Teledermatology is reliable for initial triage of patients, according to a study published online.

Tretin-X Cream Available for Acne Treatment

Onset Dermatologics announced the availability of Tretin-X (tretinoin) Cream 0.075%. Tretin-X Cream is indicated for the topical treatment of acne vulgaris.

New Retin-A Micro Gel Strength Approved

FDA has approved Retin-A Micro (tretinoin; Valeant) gel microsphere 0.08%, a new strength of Retin-A Micro gel.

Nonmelanotic Invasive Skin Cancer Tied to Agent Orange

Agent Orange (2,3,7,8-tetrachlorodibenzodioxin) exposure is associated with increased incidence of nonmelanotic invasive skin cancer.

Mirvaso Shows Positive Long-Term Study Results

Galderma has announced that in a one-year, open-label, non-comparative study, Mirvaso (brimonidine) topical gel was demonstrated to be safe and effective when used once daily for up to 12 months.

Botanical Extracts May Aid in Lightening Hyperpigmentation

Botanical extracts may be helpful in the treatment of hyperpigmentation, although identification of hyperpigmentation subtype may be important for treatment prognosis.

Cure for Baldness on the Horizon?

Scientists might be able to offer "hair-challenged" males a new glimmer of hope when it comes to reversing baldness.

FDA to Review MPI-2505 NDA for RA, Psoriasis

Medac Pharma announced that the FDA has accepted for review its New Drug Application (NDA) for its lead product candidate MPI-2505 (methotrexate).

Lasers May Aid in Treatment of Onychomycosis

Lasers may be a promising treatment for onychomycosis but larger studies are needed to determine optimal treatment conditions.

Higher Melatonin, Lower Prostate CA Risk?

Men with higher levels of melatonin may have a lower risk of developing prostate cancer.

Otrexup Injection Launched for RA, Psoriasis

Antares Pharma announced the availability of Otrexup (methotrexate for subcutaneous injection) for once-weekly self-administration with a single-dose disposable auto-injector.

Biomarker Identified in Systemic Sclerosis Predicts Progression

Patients with systemic sclerosis have elevated levels of CXCL4, which predicts disease risk and progression.

Minimally Invasive Treatment Temporarily Improves Acne

A single facial fractional radiofrequency microneedle (FRM) treatment temporarily reduces sebum secretion and reduces acne severity.

Stage III/IV Melanoma Patients at Risk for New Primaries

A higher incidence of new primary melanomas was observed in patients with Stage III/IV melanoma who were male or who had a history of multiple primary melanomas.

Review Confirms Benefit of Laser Tx for Hypertrophic Scars

Laser therapy is safe and effective for hypertrophic scar management.

AAD Issues Top Five Choosing Wisely Recommendations

The top five dermatology-related issues that physicians and patients should question have been released by the American Academy of Dermatology (AAD) as part of the Choosing Wisely campaign.

Varithena Approved for Varicose Veins Treatment

BTG plc announced that the FDA has approved Varithena (polidocanol injectable foam) for the treatment of patients with incompetent veins and visible varicosities of the great saphenous vein (GSV) system.

Unemployment Linked to Accelerated Biological Aging

Young adult men who are unemployed for long periods have shorter telomeres, a sign of accelerated biological aging.

3D Imaging Captures Changes in Port Wine Stains

Three-dimensional (3D) high precision surface imaging can be used to monitor changes in the area and volume of port wine stains following laser treatment.

Interim Overall Survival Results Announced for T-VEC in Melanoma Study

Amgen announced interim overall survival (OS) results from a pivotal Phase 3 trial evaluating talimogene laherparepvec in patients with unresected stage IIIB, IIIC, or IV melanoma compared to granulocyte-macrophage colony-stimulating factor (GM-CSF).

Luzu Cream Approved for Skin Fungal Infections

Valeant announced that the New Drug Application for Luzu (luliconazole) Cream, 1% has been approved by the FDA.

FDA Addresses Improper OTC Topical Antiseptic Use

The FDA is requesting label and packaging changes to improve the safety of certain over-the-counter (OTC) topical antiseptic products.

Twin Study Shows Smoking Causes Premature Facial Aging

Visual evidence in identical twins shows that smoking hastens facial aging, particularly in the middle and lower thirds of the face.

AACR: Melanoma Biomarker Predicts Drug Sensitivity

Monitoring changes in a biomarker can predict whether a class of melanomas will be sensitive to a particular class of drugs.

Laser Treatment Interval Doesn't Affect Benefit of Acne Scars

Fractional CO2 laser treatment is safe and seems effective for atrophic acne scars.

Psoriasis Linked to Increased Risk of Chronic Kidney Disease

Moderate or severe psoriasis is associated with chronic kidney disease.

Ablative Carbon Dioxide Laser Effective for Rhinophyma

Good cosmetic outcomes are possible using fractionated ablative carbon dioxide laser therapy for mild-to-moderate cases of rhinophyma.

First SC Methotrexate Auto-Injector Approved

Antares Pharma announced that the FDA has approved Otrexup injection, the first SC methotrexate for once-weekly self-administration with an easy-to-use, single-dose, disposable auto-injector.

Melanoma Patients Increase Sun Exposure After Diagnosis

Patients with cutaneous malignant melanoma (CMM) may actually increase their exposure to ultraviolet radiation in the first three years after diagnosis.

Rosacea Risk Higher in Female Migraine Sufferers

There is a slight increased risk of rosacea among females with migraines.

Phototherapy Affects Serum 25(OH)D Levels

Phototherapy with ultraviolet (UV) A1 radiation induces a reduction in serum 25-hydroxyvitamin D3 (25[OH]D) levels, whereas narrowband UVB (UVBnb) and UVA/UVBnb induces significant increases in serum 25(OH)D.

Review: Low-Level Laser Tx Effective for Hair Growth

Low-level laser therapy (LLLT) seems to be effective and safe for hair growth in men and women.

Rarely 'Too Early' for Appearance-Enhancing Procedures

The effects of appearance-enhancing procedures such as neuromodulators, fillers, and light or laser treatments have lasting effects and can rarely be used "too early".

Botox Injection Gains New Indication

Botox Cosmetic has been approved for an additional indication to temporarily treat moderate-to-severe crow's feet lines.

Physicians Rarely Remind Patients to Use Sunscreen

Physicians very rarely educate patients regarding the use of sunscreen and sun-protective behaviors.

MNK-795 Efficacious for Acute Pain after Bunionectomy

MNK-795 (Mallinckrodt) achieved the primary endpoint in a Phase 3 efficacy trial for the treatment of moderate to severe acute pain following bunionectomy.

Mirvaso Topical Gel Approved for Facial Erythema of Rosacea

The FDA has approved Galderma's Mirvaso (brimonidine) topical gel for the topical treatment of the facial erythema associated with rosacea in adults 18 years or older.

Vitamin D Supplementation Beneficial in Atopic Dermatitis

Vitamin D may influence atopic dermatitis, and supplementation is associated with reduced disease severity.

New Test Identifies 193 Different Disease-Causing Microorganisms

The FDA has approved marketing of bioMerieux Inc.'s VITEK MS, the first mass spectrometer system for automated identification of 193 different microorganisms known to cause serious illness in humans.

IID: Sleep Quality Impacts Skin Function, Aging in Women

For premenopausal women, sleep quality is associated with skin function and aging.

Nontreatment, Undertreatment of Psoriatic Disease Quantified

Nontreatment and undertreatment of psoriasis and psoriatic arthritis, including severe disease, is widespread in the United States.

Comorbidity Increases With Increasing Severity of Psoriasis

For patients with psoriasis, major medical comorbidity increases with increasing severity of disease.

Photoprotection-Deficient Patients With CLE Identified

Several subgroups of patients with cutaneous lupus erythematosus (CLE) are deficient in their use of photoprotection

Naftin Gel 2% Approved for Interdigital Tinea Pedis

Merz announced that the FDA has approved Naftin Gel 2% for the treatment of interdigital-type tinea pedis.

Does Delaying Skin Closure Reduce Surgical Infections?

Delayed primary skin closure may reduce the risk of infection after surgery, but the current studies are not definitive due to poor design.

New Dosage Strength for Doryx

Warner Chilcott announced the availability of a new 200mg dosage strength for Doryx (doxycycline hyclate) delayed-release tablets.

Antibiotic Exposure in Infancy Linked to Subsequent Eczema

Exposure to antibiotics in the first year of life is associated with an increased likelihood of eczema, with increasing risk seen for each additional course of antibiotics.

Aquacel Ag Foam Dressing Now Available

ConvaTec has launched Aquacel Ag Foam dressing, the latest addition to the Aquacel family of wound management products.

Daily Sunscreen Use During Middle-Age Slows Skin Aging

Daily sunscreen use can slow skin aging in middle-aged adults.

Weight Loss Reduces Severity of Psoriasis

Overweight patients with psoriasis have reduced disease severity and improved skin-related quality of life after weight loss.

Comorbidities Common With Alopecia Areata

Comorbid conditions often accompany alopecia areata.

Recall: Particulate Discovered in Methotrexate Vials

Sandoz is recalling two lots of Methotrexate Sodium injectable after discovering particulate matter in the vials.

Twitter Reveals Popular Health Beliefs About Acne

Twitter can teach health care providers about popular health-related beliefs regarding acne.

Sturge-Weber Syndrome, Port Wine Stains Genetically Linked

A somatic single nucleotide mutation causes Sturge-Weber syndrome and port wine stains.

FDA Proposes to Increase User Awareness of Sunlamp Risks

The U.S. FDA has proposed an order to reclassify sunlamp products from a low-risk to a moderate-risk device, which would require comprehensive risk labeling on such products.

Topical Cream Granted Breakthrough Therapy for Rare Connective Tissue Disorder

SD-101 was granted Breakthrough Therapy designation for the treatment of skin blisters and erosions caused by Epidermolysis Bullosa.

AAP Endorses Pediatric Acne Management Guidelines

The American Academy of Pediatrics has reviewed and endorsed the recommendations of the American Acne and Rosacea Society for the clinical management of pediatric acne.

Aurstat Anti-Itch Hydrogel Available for Eczema

Aurstat Anti-Itch Hydrogel, a non-steroidal treatment from Onset Dermatologics, provides relief of pain, burning, and itching associated with various dermatoses.

Orphan Drug Designation Granted for Pain Drug XEN402

The FDA has granted Orphan Drug designation to Teva Pharmaceutical and Xenon Pharmaceutical's investigation drug XEN402, which is being developed for the treatment of pain associated with erythromelalgia.

HPV Exposure in Family, School Linked to Wart Development

For schoolchildren, exposure to human papillomavirus (HPV)-causing warts in the family and school class is associated with an increased risk of wart development.

Relative Proportion of MRSA Increasing in S. aureus Isolates

The relative proportion of methicillin-resistant Staphylococcus aureus (MRSA) is increasing in S. aureus isolates, and methicillin-sensitive S. aureus (MSSA) is becoming increasingly resistant to antibiotics.

Topicort Spray Approved to Treat Plaque Psoriasis

Taro Pharmaceuticals has received FDA approval for its New Drug Application for Topicort Topical Spray, a corticosteroid indicated for the treatment of plaque psoriasis in patients 18 years and older.

Elorac's Topical Naloxone Lotion Granted Fast Track Designation

The FDA has granted Fast Track designation to Elorac's naloxone topical lotion, an opiate antagonist with no agonist activity, for the relief of pruritus in patients with cutaneous T-cell lymphoma.

Allegra Anti-Itch Cream Line Now Available

Allegra Anti-Itch Cooling Relief Cream and Allegra Anti-Itch Intensive Relief Cream have been released. Each cream provides itch relief from reactions to skin irritations for patients 2 years and older.

Severe Male Baldness Linked to Coronary Heart Disease

Male vertex baldness is associated with an increased risk of coronary heart disease, with the association depending on the severity of baldness.

More Research Needed on Use of Prebiotics in Infants

There is some evidence that supplementation with a prebiotic may prevent eczema in formula-fed infants, but more research is needed before routine use of prebiotics can be recommended.

AmLactin Cerapeutic Restoring Body Lotion Launched

Upsher-Smith has launched its latest skin care product, AmLactin Cerapeutic Restoring Body Lotion. The lotion contains alpha-hydroxy acids, which are effective at exfoliating and hydrating the skin, as well as three skin identical ceramides, which strengthen the skin's protective moisture barrier.

Psoriasis Tied to Increased Risk of New-Onset Diabetes

Psoriasis is significantly tied to an increased risk of new-onset diabetes mellitus, according to a new study.

To Block UV Rays, Even the Poorest Handheld Umbrellas Work

Handheld umbrellas are effective at blocking ultraviolet radiation. The poorest performing umbrella still blocked an average of 77% UVR, according to researchers.

SilvrSTAT Wound Dressing Gel Now Available

SilvrSTAT Antibacterial Wound Dressing Gel , from ABL Medical, manages 1st and 2nd-degree burns, stasis ulcers, pressure ulcers, diabetic ulcers, lacerations, abrasions, skin tears, surgical incision sites, device insertion site wounds, and graft and donor sites. SilvrSTAT is available in 1oz or 3oz tubes.

Specific Strains of P. acnes Linked to Acne and Healthy Skin

Specific strains of the skin commensal Propionibacterium acnes are associated with acne and with healthy skin.

Phase 3b Results Announced for ATX-101 for Reduction of Submental Fat

Kythera Biopharmaceuticals announced positive interim results from a Phase 3b study (ATX-101-11-26) to evaluate the safety and efficacy of ATX-101, an investigational injectable drug for the reduction of unwanted submental fat (SMF), also known as double chin.

AAD: Skin Changes Can Be First Sign of Underlying Condition

Skin changes, including new rash, new growths, discoloration, and changes in texture, could be among the first signs indicating an underlying medical condition.

AAD: Complications of Tattoos and Tattoo Ink Discussed

Complications linked to tattoos and tattoo inks include allergic reactions, serious infections, and reactions that can be mistaken for skin cancer.

Review: Growing Body of Evidence Linking Diet to Acne

Evidence suggests that there may be a connection between acne and diet, particularly foods with a high glycemic index.

Isotretinoin Not Linked to Increased Risk of IBD

Among women of reproductive age, isotretinoin is not associated with an increased risk for inflammatory bowel disease (IBD), including ulcerative colitis (UC) or Crohn's disease (CD).

FDA Accepts NDA for Otrexup for Subcutaneous Delivery of Methotrexate

Antares Pharma announced that the FDA has accepted for review their New Drug Application (NDA) for Otrexup, a potential new product for the SQ delivery of methotrexate (MTX) using Medi-Jet technology.

Expanded Pediatric Use for Epiduo Gel

Galderma Laboratories announced that the FDA has approved Epiduo (adapalene and benzoyl peroxide) Gel for the treatment of acne in children as young as 9 years old.

Tri-Luma Cream Available Again for Melasma

Galderma announced that Tri-Luma (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) cream is available again for short-term treatment (up to 8 weeks) of moderate to severe melasma of the face, in the presence of measures for sun avoidance, including the use of sunscreens.

Doctors' Perceptions of Psoriasis Therapies Vary

Doctors who treat patients with psoriasis show wide variation in their beliefs about the safety and effectiveness of psoriasis treatments.

Fast Food Tied to Risk of Severe Asthma in Children, Teens

Eating fast food ≥3 times per week is associated with an increased risk of severe asthma, rhinoconjunctivitis, and eczema among children and adolescents, while eating fruit seems to be protective against severe asthma.

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