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DEMADEX
Edema
Hypertension
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Drug Name:

DEMADEX Rx

Generic Name and Formulations:
Torsemide 5mg, 10mg, 20mg, 100mg; scored tabs.

Company:
Roche Laboratories

e-Prescribe this drug via Surescripts


Therapeutic Use:

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Indications for DEMADEX:

Edema.

Adult Dose for DEMADEX:

Give IV dose over a period of 2 minutes. Edema due to CHF: 10–20mg once daily oral or IV, if needed titrate upwards by doubling dose until desired response; max 200mg daily. Edema due to renal disease: 20mg once daily oral or IV, if needed titrate upwards by doubling dose until desired response; max 200mg daily. Edema due to hepatic disease: 5–10mg once daily oral or IV, give with aldosterone antagonist or potassium-sparing diuretic, may titrate upwards by doubling dose until desired response is achieved; max 40mg daily.

Children's Dose for DEMADEX:

Not recommended.

See Also:

Torsemide Injection

Pharmacological Class:

Diuretic (loop).

Contraindications:

Anuria. Sulfonamide allergy.

Warnings/Precautions:

Hepatic disease with cirrhosis and ascites. Monitor electrolytes, BUN, creatinine, uric acid, and fluids. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Lithium and salicylate toxicity. Caution with NSAIDs. Antagonized by probenecid and indomethacin. Give oral dose 2 hours before or 4 hours after cholestyramine. Ototoxicity with aminoglycosides and ethacrynic acid.

Adverse Reactions:

Dizziness, headache, nausea, weakness, vomiting, hyperglycemia, hyperuricemia, hypokalemia, excessive thirst, hypovolemia, impotence, esophageal hemorrhage, dyspepsia.

Note:

Formerly known under the brand name Demadex Injection.

How Supplied:

Tabs—100; Ampules—Contact supplier

Indications for DEMADEX:

Hypertension.

Adult Dose for DEMADEX:

5mg once daily, may increase to 10mg once daily. Give IV dose over a period of 2 minutes.

Children's Dose for DEMADEX:

Not recommended.

See Also:

Torsemide Injection

Pharmacological Class:

Diuretic (loop).

Contraindications:

Anuria. Sulfonamide allergy.

Warnings/Precautions:

Hepatic disease with cirrhosis and ascites. Monitor electrolytes, BUN, creatinine, uric acid, and fluids. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Lithium and salicylate toxicity. Caution with NSAIDs. Antagonized by probenecid and indomethacin. Give oral dose 2 hours before or 4 hours after cholestyramine. Ototoxicity with aminoglycosides and ethacrynic acid.

Adverse Reactions:

Dizziness, headache, nausea, weakness, vomiting, hyperglycemia, excessive urination, hyperuricemia, hypokalemia, excessive thirst, hypovolemia, impotence, esophageal hemorrhage, dyspepsia.

How Supplied:

Tabs—100; Ampules—Contact supplier