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Constipation and bowel cleansers
Only 4 drugs may be compared at once

Generic Name and Formulations:

Polyethylene glycol 3350 60g, sodium chloride 1.46g, potassium chloride 0.745g, sodium bicarbonate 1.68g, sodium sulfate 5.68g; per liter of soln; pwd for reconstitution.

Select therapeutic use:

Indications for COLYTE:

Bowel cleansing before colonoscopy or barium enema exam.


After fasting for >3hrs, 240mL orally every 10mins or 20–30mL/min by NG tube until fecal discharge is clear. Usual dose 3–4L. Only clear liquids until exam.


Not established.


GI obstruction or perforation. Gastric retention. Toxic colitis. Toxic megacolon. Ileus.


Severe ulcerative colitis. Impaired gag reflex. Semi- or unconsciousness. Risk of aspiration or regurgitation. Correct fluid and electrolyte abnormalities prior to initiation. Increased risk of arrhythmias (eg, history of prolonged QT, uncontrolled arrhythmias, recent MI, unstable angina, CHF or cardiomyopathy); do pre-dose and post-colonoscopy ECGs. History of seizures. Rule out GI obstruction or perforation. Maintain adequate hydration. Renal impairment. Pregnancy (Cat.C). Nursing mothers.


Concomitant drugs that may increase the risk of fluid and electrolyte disturbances or adverse events. Drugs administered within 1hr of start of Colyte may not be absorbed. Increased risk of ischemic colitis with concomitant stimulant laxatives.

See Also:


Pharmacological Class:

Isosmotic bowel cleanser.

Adverse Reactions:

Nausea, abdominal fullness or bloating, cramps, vomiting, anal irritation; serious: colonic mucosal ulceration, ischemic colitis; rare: arrhythmias.

How Supplied:

Colyte w. Flavor Packs—4L (disposable jug w. 3 flavor packs); Colyte—4L (disposable jug)

COLYTE 4 liter bottle of powders (Qty:1)

appx. price $62.00