COLESTID TABLETS Rx

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COLESTID TABLETS

Hyperlipoproteinemias
Only 4 drugs may be compared at once

Generic Name and Formulations:

Colestipol HCl (micronized) 1g.

Company:

Pfizer Inc.

Select therapeutic use:

Indications for COLESTID TABLETS:

Adjunct to diet to lower elevated serum total-C and LDL-C in primary hypercholesterolemia.

Adult:

Do not crush, chew, or cut. Take with adequate fluids. Initially 2g once or twice daily, then increase by 2g once or twice daily at 1–2 month intervals. Usual maintenance: 2–16g/day in 1 or more divided doses.

Children:

Not established.

Warnings/Precautions:

Obtain baseline serum cholesterol, LDL-C, and triglycerides, and monitor during therapy. Consider reducing dose, discontinuing, or alternative therapy if significant increase in triglycerides occur. May need Vit. A, D and K supplementation with long-term therapy. Exclude secondary causes of hypercholesterolemia (eg, hypothyroidism, diabetes, nephrotic syndrome, dysproteinemias, obstructive liver disease, alcoholism). Constipation; increase fluid/fiber intake or add a stool softener. Hemorrhoids. Phenylketonurics (flavored Colestid). Monitor thyroid function. Pregnancy. Nursing mothers.

Interactions:

Reduces absorption of folic acid, fat soluble vitamins, thiazides, furosemide, tetracycline, penicillin G, gemfibrozil, mycophenolic acid, others; monitor digitalis, propranolol; give other drugs at least 1hr before or 4hrs after. May affect absorption of oral phosphate supplements, hydrocortisone.

See Also:

COLESTID

Pharmacological Class:

Bile acid sequestrant.

Adverse Reactions:

Constipation, fecal impaction, aggravated hemorrhoids, abdominal pain/cramp, gas, indigestion, heartburn, diarrhea, nausea, vomiting, Vit. A, D, K deficiencies or hyperchloremic acidosis with prolonged use.

How Supplied:

Unflavored 5g pkt—30, 90; Bulk—300g, 500g (w. scoop); Flavored 7.5g pkt—60; Bulk—450g (w. scoop); Tabs—120