Clonazepam Orally-Disintegrating Tablets CIV

Indications for Clonazepam Orally-Disintegrating Tablets:

Panic disorder.

Adult Dose for Clonazepam Orally-Disintegrating Tablets:

>18yrs: initially 0.25mg twice daily; after 3 days increase to 1mg/day; then may increase every 3 days by 0.125–0.25mg twice daily; max 4mg/day. Orally-disintegrating tabs: dissolve in mouth; swallow with or without water.

Children's Dose for Clonazepam Orally-Disintegrating Tablets:

<18yrs: not recommended.

See Also:

KLONOPIN

Pharmacological Class:

Benzodiazepine.

Contraindications:

Significant liver disease. Acute narrow-angle glaucoma.

Warnings/Precautions:

Suicidal tendencies (monitor). Chronic respiratory disease. Renal impairment. Avoid abrupt cessation. Reevaluate periodically. Monitor blood counts, liver function. Elderly. Labor & delivery, pregnancy (Cat.D), nursing mothers: not recommended.

Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Adjust anticonvulsants if needed. Absence seizures with valproate. Caution with drugs that inhibit CYP3A (eg, azole antifungals). Antagonized by CYP450 inducers (eg, phenytoin, carbamazepine, phenobarbital).

Adverse Reactions:

CNS effects (esp. depression), hypersalivation, liver disorders, GI upset, blood dyscrasias, paradoxical reactions.

Note:

Formerly known under the brand name Klonopin.

How Supplied:

Tabs—100; Orally-disintegrating tabs—contact supplier

Indications for Clonazepam Orally-Disintegrating Tablets:

Lennox-Gastaut syndrome, akinetic and myoclonic seizures. Absence seizures refractory to succinimides.

Adult Dose for Clonazepam Orally-Disintegrating Tablets:

Initially up to 0.5mg 3 times daily. Increase if needed every 3 days by 0.5–1mg daily; max 20mg daily. Orally-disintegrating tabs: dissolve in mouth; swallow with or without water.

Children's Dose for Clonazepam Orally-Disintegrating Tablets:

<10yrs or <30kg: initially 0.01–0.03mg/kg per day, but not >0.05mg/kg per day in 2–3 divided doses. Increase if needed every 3 days by 0.25–0.5mg daily. Maintenance: 0.1–0.2mg/kg per day in 3 equally divided doses. Orally-disintegrating tabs: dissolve in mouth; swallow with or without water.

See Also:

KLONOPIN

Pharmacological Class:

Benzodiazepine.

Contraindications:

Significant liver disease. Acute narrow-angle glaucoma.

Warnings/Precautions:

May increase or precipitate tonic-clonic seizures. Suicidal tendencies (monitor). Chronic respiratory disease. Renal impairment. Avoid abrupt cessation. Monitor blood counts, liver function. Elderly. Labor & delivery, pregnancy (Cat.D), nursing mothers: not recommended.

Interactions:

Potentiates CNS depression with alcohol, other CNS depressants. Adjust anticonvulsants if needed. Absence seizures with valproate. Caution with drugs that inhibit CYP3A (eg, azole antifungals). Antagonized by CYP450 inducers (eg, phenytoin, carbamazepine, phenobarbital).

Adverse Reactions:

CNS effects (esp. depression), hypersalivation, liver disorders, GI upset, blood dyscrasias, paradoxical reactions.

Note:

Formerly known under the brand name Klonopin.

How Supplied:

Tabs—100; Orally-disintegrating tabs—contact supplier