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CLIMARA PRO
Menopause and HRT
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Drug Name:

CLIMARA PRO Rx

Generic Name and Formulations:
Estradiol 0.045mg + levonorgestrel 0.015mg; per day; transdermal system.

Company:
Bayer Healthcare Pharmaceuticals Inc.

e-Prescribe this drug via Surescripts


Therapeutic Use:

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Indications for CLIMARA PRO:

Moderate to severe vasomotor symptoms of menopause in women with an intact uterus. Postmenopausal osteoporosis prevention.

Adult Dose for CLIMARA PRO:

Apply 1 patch once weekly to lower abdomen (avoid waistline); rotate application sites.

Children's Dose for CLIMARA PRO:

Not applicable.

Pharmacological Class:

Estrogen + progestin.

Contraindications:

Undiagnosed abnormal genital bleeding. Thromboembolic disorders. Thrombophlebitis. Breast or estrogen-dependent carcinoma. Pregnancy (Cat.X).

Warnings/Precautions:

Familial hyperlipoproteinemia or history of breast cancer. Hepatic insufficiency. Conditions aggravated by fluid retention. Endometriosis. Gallbladder disease. Bone disease associated with hypercalcemia. Do initial complete physical and repeat annually (include Pap smear, mammogram, and BP). Discontinue if visual abnormalities, hypertension or jaundice occurs and during immobilization, or at least 2 weeks before surgery associated with increased risk of thromboembolism. May interfere with lab tests (see literature). Nursing mothers.

Adverse Reactions:

See literature. May increase risk of breast cancer, gallbladder disease, thromboembolic disorders, others. Local irritation, fluid retention, breakthrough bleeding, mastodynia, nausea, abdominal cramps, headache, dizziness, intolerance to contact lenses.

How Supplied:

Patches—4

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