CINQAIR Rx

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CINQAIR

Asthma/COPD
Only 4 drugs may be compared at once

Generic Name and Formulations:

Reslizumab 100mg/10mL; soln for IV infusion; preservative-free.

Select therapeutic use:

Indications for CINQAIR:

As add-on maintenance treatment of severe asthma in patients ≥18yrs old, and with an eosinophilic phenotype.

Limitations Of use:

Not for treating other eosinophilic conditions. Not for relief of acute bronchospasm or status asthmaticus.

Adult:

Give by IV infusion over 20–50mins. ≥18yrs: 3mg/kg once every 4 weeks.

Children:

<18yrs: not established.

Warnings/Precautions:

Should be administered by healthcare provider prepared to manage anaphylaxis. Observe patient for a period of time post-infusion; discontinue immediately if severe systemic reactions or anaphylaxis occur. Not for treating acute asthma symptoms or exacerbations. Treat pre-existing helminth infections before initiating therapy; discontinue Cinqair if treatment-resistant infection occurs while on therapy until resolves. Avoid abrupt cessation of systemic or inhaled corticosteroids upon Cinqair initiation; reduce dose gradually if appropriate. Reduction may be associated with systemic withdrawal symptoms and/or unmask previously suppressed conditions. Pregnancy. Nursing mothers.

Pharmacological Class:

Interleukin-5 antagonist.

Adverse Reactions:

Oropharyngeal pain, elevated CPK, myalgia; anaphylaxis, malignancy.

Generic Availability:

NO

How Supplied:

Single-use vial—1