CHF And Arrhythmias

Light, Moderate Alcohol Intake May Protect Against All-Cause, CVD Death

August 15, 2017

Risk of mortality for all causes, cancer up for adults with heavy alcohol consumption, binge drinking.

Diuretic Linked to Acute Pancreatitis in Patient with Coronary Artery Disease

By August 14, 2017

Furosemide-induced acute pancreatitis can occur several hours to up to 7 weeks after starting treatment; dose may also play a role. This patient, the authors note, fell into the category of "long-term latency" and "low-dosage (40mg)"

Non-Invasive ECG Device Gets FDA Clearance

By August 09, 2017

Clinical data from the Turbulence study (n=1,807) showed CADence had comparable performance to a SPECT nuclear stress test in excluding obstructive CAD in patients with chest pain and risk factors.

CVD Risk Significantly Heightened in Years Follow Severe Infection

August 09, 2017

While the first year after infection has the highest risk (adjusted hazard ratio [aHR], 6.33), an increased risk persists for the second (aHR, 2.47) and third year (aHR, 2.12) after infection.

Heart Failure with Preserved Ejection Fraction: Treatments Compared

By August 08, 2017

A total of 25 randomized controlled trials involving 18,101 patients were included for the analysis.

Vitamin B Effects on Fracture Risk Examined in Women at High CVD Risk

August 07, 2017

The researchers found that B vitamin supplementation had no significant effect on non-spine fracture risk (relative hazard, 1.08; 95% confidence interval, 0.88 to 1.34).

FDA Approves CaroSpir, an Oral Suspension Formulation of Spironolactone

By August 07, 2017

CaroSpir, an aldosterone antagonist, works primarily through competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tube.

Statin Rx Given to Less than Half of Stroke Patients at Discharge

August 03, 2017

The researchers restricted analyses to 323 of the 666 patients with incident stroke who were not statin users at the time of admission and had no history of atrial fibrillation.

Scientists Correct Disease-Causing Gene Mutation in Human Embryos

By August 02, 2017

Using the gene-editing tool CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) the researchers worked with healthy donated human oocytes and sperm carrying the genetic mutation that causes cardiomyopathy.

Canagliflozin CV Biomarker Effects Examined in Diabetes Patients

August 02, 2017

The researchers observed increases in serum NT-proBNP and serum hsTnI levels in placebo recipients, but these levels remained largely unchanged in canagliflozin recipients.

Cardiovascular Disease Correlated to Daily Sodium Intake Threshold

August 01, 2017

ESI >3.7 g/day correlated with strain parameters and e' velocity, while ESI ≤3.7 g/day was not, after adjustment for speckle-tracking analyst, image quality, study site, age, sex, smoking status, alcohol use, daily blocks walked, diuretic use, estimated glomerular filtration rate, left ventricular mass, ejection fraction, and wall motion score index.

Repatha sBLA Under Priority Review for MACE Risk Reduction

By July 28, 2017

Results showed that the evolocumab group had a statistically significant 15% reduction (P<0.001) in the risk of extended MACE composite (primary) endpoint - which included hospitalization for unstable angina, coronary revascularization, heart attack, stroke or cardiovascular death - compared to placebo group.

Correlation Between Weight and Heart Failure Explored

July 20, 2017

The investigators found that people who increased their weight by as little as 5% were more likely to have thickening and enlargement of the left ventricle.

Fixed-Dose vs. Off-Label Combos Compared in Black Patients with Heart Failure

By July 18, 2017

Study authors performed an exploratory propensity-matched cohort study using Medicare data to assess overall survival differences between these treatments in patients with at least 80% 1-year medication adherence levels.

Researchers Develop Silicone Heart that Beats Almost Like Human Heart

By July 13, 2017

Although the heart worked in a similar fashion to a real human heart, the material could only withstand the strain of pumped circulation for roughly 3,000 beats, or for a period of 30 to 45 minutes.

Vasodilators May Help Prevent Clots, Stenosis with Stents

July 12, 2017

"If clinical trials show that sildenafil reduces restenosis after stent placement, it could be used in the clinical setting right away because the drug is already used in the real world for other purposes," said the lead author Han-Mo Yang.

The Rate of At-Home Medication Errors Has Doubled

July 11, 2017

The rate of serious medication errors rose from 1.09 for every 100,000 Americans in 2000 to 2.28 per 100,000 by 2012.

Cardiovascular, Cerebrovascular Risk Examined for LABA/LAMA in COPD

By July 07, 2017

Overall results demonstrated that for the LABA/LAMA cohort cardiovascular event frequency was 2.11% compared to 3.41% in the LABA/ICS cohort.

Food Type, Timing Has No Clinically Relevant Impact on Rivaroxaban

By July 06, 2017

Currently, the prescribing information recommends 20mg once daily with an evening meal for the AF indication, and 15mg twice daily with food for 21 days, followed by 20mg once daily with food for the remainder of treatment for the DVT/PE indications.

Herpes Zoster Linked to Increased Stroke, Heart Attack Risk

July 06, 2017

The researchers found that the HZ group had a 59% higher risk of myocardial infarction and a 35% higher risk of stroke than the others.

Does Niacin Therapy Prevent Cardiovascular Disease Events?

By June 28, 2017

Niacin (nicotinic acid) decreases LDL cholesterol and triglycerides and increases HDL cholesterol levels. However, its benefits are "controversial," when it comes to reducing cardiovascular events.

Novel CETP Inhibitor Shows Coronary Improvements in Phase 3 Study

By June 27, 2017

The full results of the REVEAL trial will be announced at the European Society of Cardiology meeting on August 29.

Do &#946;-Blockers Reduce Death Risk in Acute MI without Heart Failure?

June 01, 2017

No significant difference in mortality for MI patients without HF, LVSD with, without -blocker use

Reversing Heart Damage in Meth Users Possible with Cessation

May 31, 2017

Only those who stop using the drug can reap cardiac benefits, researchers say

AHA/ACC Guidelines for Valvular Heart Disease Management Updated

March 22, 2017

Updated recommendations include modified recommendations for TAVR and surgical AVR

Heart Failure Risk Increased in RA Patients

March 14, 2017

High disease activity linked to all types of heart failure, especially non-ischemic heart failure

Heart Failure Patients Benefit from Omega-3 Supplementation

March 14, 2017

And supplements still deemed useful for patients who have had a recent myocardial infarction

Unique Therapy for Advanced Heart Failure Granted Fast Track Status

By February 21, 2017

Ixmyelocel-T is an investigational autologous expanded multicellular therapy administered via transendocardial catheter-based injections.

Hormone ID'd as Link Between Bone and Vascular Disease

January 11, 2017

Significant association with carotid-femoral pulse wave velocity persists after multivariable adjustment

Imbibing Excessively Will Not Help Your Heart, Says New Study

By January 03, 2017

Previous literature had suggested that moderate alcohol consumption may prevent heart attack and congestive heart failure.