CHF And Arrhythmias

Clinical Significance of Genetic Variations in CYP2D6 Investigated in HF Patients

By June 21, 2018

According to HF guidelines, beta-blockers must be titrated to a specific target dose in order to obtain their morbidity and mortality benefit in HF patients.

Increased Risk of MI, Ischemic Stroke After COPD Exacerbation

June 19, 2018

Greater risks were seen following a severe exacerbation (incidence rate ratios, 2.58 and 1.97 for myocardial infarction and ischemic stroke, respectivley) than after a moderate exacerbation (incidence rate ratios, 1.58 and 1.45, respectively).

Risk of CV Events Down With Med Diet Plus Olive Oil, Nuts

June 19, 2018

Participants who were at high cardiovascular risk were randomized to 1 of 3 diets: a Mediterranean diet supplemented with extra-virgin olive oil, a Mediterranean diet supplemented with mixed nuts, or a control diet featuring advice to reduce dietary fat.

Good Sleep Tied to Better Cardiometabolic Health in Youths

June 15, 2018

"These results support the need to assess the role of sleep quantity and quality interventions as strategies for improving cardiovascular risk profiles of adolescents," the authors write.

Screen Does Not Cut Abdominal Aortic Aneurysm Mortality in Men

June 15, 2018

"AAA screening in Sweden did not contribute substantially to the large observed reductions in AAA mortality," the authors write. "The small benefit and substantially less favorable benefit-to-harm balance call the continued justification of the intervention into question."

Personalized Goals, Cash Motivate Heart Patients to Exercise

June 14, 2018

The researchers found that patients in the incentive arm had a significantly greater increase in mean daily steps from baseline during the ramp-up (P<.01), maintenance (P<.001), and follow-up (P<.01) phases.

Work Stress May Increase Risk of Developing Atrial Fibrillation

June 13, 2018

The researchers found that job strain was associated with an almost 50% increased risk of atrial fibrillation (hazard ratio [HR], 1.48; 95% confidence interval, 1.00 to 2.18) after adjustment for age, sex, and education.

USPSTF: No to ECG Screening to Prevent CVD in Low-Risk Adults

June 13, 2018

The researchers found that it is very unlikely that the information from resting or exercise ECG would result in a change in a patient's risk category that would lead to a change in treatment or improve health outcomes for asymptomatic adults at low risk for CVD events.

Better Dietary Patterns Among US Adults Could Save Billions

June 11, 2018

Cost savings were estimated at $66.9 and $135 billion, respectively, if the diet quality of US adults were to improve to achieve 80% of the maximum healthy eating index 2015 and mediterranean diet scores.

Erectile Dysfunction Independently Tied to CV Events

June 11, 2018

Participants with erectile dysfunction were more likely to have diabetes mellitus; a family history of CHD; and to use β-blocker, antihypertensive, lipid-lowering, and antidepressant medications.

Malpractice Damage Caps Associated With Change in CAD Testing, Tx

June 08, 2018

Reduced revascularization rates were seen after ischemic evaluation among new-cap physicians (−23%), driven by fewer percutaneous coronary interventions.

Synthetic Cannabis May Increase Ischemic Cardiomyopathy Risk

June 08, 2018

Ischemic cardiomyopathy described in young male, which was attributed to synthetic cannabinoid use

Improved calculations suggest major changes to statin, aspirin, and blood pressure Tx

June 06, 2018

Updated risk calculations suggest that fewer people should be classified within the high-risk category for CVD.

Radial-artery grafts outperform saphenous-vein grafts when used in CABG

June 04, 2018

Patients undergoing coronary artery bypass grafting (CABG) who received a radial-artery graft rather than a saphenous-vein graft (both groups also received an internal-thoracic-artery graft) experienced fewer major adverse cardiac events at a mean follow-up of 60 months.

No Consistent Cardiovascular Benefit Seen for Supplements

June 01, 2018

The researchers found that the evidence for preventive benefits (folic acid for cardiovascular disease, folic acid and B-vitamins for stroke), no effect (multivitamins, vitamins C and D, β-carotene, calcium, and selenium), or elevated risk (antioxidant mixtures and niacin [with a statin] for all-cause mortality) was generally moderate- or low-quality.

CVD Risk Up Even in Metabolically Healthy Obese Women

May 31, 2018

Compared to women with stable healthy normal-weight, women who maintained metabolically healthy obesity during follow-up were still at elevated cardiovascular risk (hazard ratio, 1.57); this risk was lower than for initially metabolically healthy women who converted to an unhealthy phenotype (hazard ratios, 1.90 and 2.74 for normal-weight and obesity, respectively).

Genomic Medicine Will Help Shift Cardio Care to Proactive Approach

May 30, 2018

Genomic medicine will help shift clinical care from reactive to proactive, say the authors.

Does Higher Protein Intake Up Heart Failure Risk in Men?

May 30, 2018

During a mean follow-up of 22.2 years, there were 334 incident heart failure cases. There was a trend toward increased risk of heart failure with higher intake of total protein.

Hyperkalemia Treatment Lokelma Gets FDA Approval

By May 21, 2018

Lokelma is a non-absorbed zirconium silicate that preferentially captures potassium in exchange for hydrogen and sodium.

Starting Exercise Even in Older Age Cuts Heart Failure Risk

May 21, 2018

The lowest heart failure risk was seen for those with persistently recommended activity (hazard ratio, 0.69), compared to those with consistently poor activity.

Acute Kidney Injury in Hospital Ups Risk of Later Heart Failure

May 18, 2018

AKI was independently associated with higher rates of the composite outcome of hospitalization for heart failure and atherosclerotic events 1-year post-discharge.

Seafood Recommended 1 to 2 Times/Week for Cardiac Benefit

May 17, 2018

Two servings of seafood per week can be sustainable and environmentally friendly, and is a recommended source of protein, vitamin D, vitamin B12, and long-chain n-3 polyunsaturated fatty acids.

Hyoscyamine Helps in A-Fib With Slow Ventricular Response

May 15, 2018

Electrocardiography documented atrial fibrillation with a slow ventricular response and right bundle branch block; blood pressure was 72/40mmHg and heart rate was 35 beats/minute.

Researchers Explore Nanofibers to Target, Treat Atherosclerosis

May 14, 2018

Compared with phosphate-buffered saline treated controls, male and female mice treated with ApoA-LXR PA had 11 and 9% plaque reduction, respectively, after 8 weeks of treatment.

Ob-Gyns Should Play Role in Reducing CVD Risk for Women

May 10, 2018

The authors note that most women consider their ob-gyn to be their primary care physician.

Vasopressin plus catecholamines lowers risk of atrial fibrillation in distributive shock

May 09, 2018

In this meta-analysis, addition of vasopressin to catecholamine vasopressors was associated with a lower risk of atrial fibrillation when compared to catecholamine monotherapy.

Marijuana Use Not Linked to Risk of Arrhythmias After Acute MI

May 09, 2018

Overall, 9.7% of both marijuana users and non-users experienced VT/VF or cardiac arrest (P=.94); 4.5 and 8.7%, respectively, experienced atrial fibrillation; and 4 and 6%, respectively, died.

At Low Temps, Air Pollution May Up Risk of Sudden Cardiac Death

May 09, 2018

"Our study demonstrates that even a small amount of air pollution on colder days could put people at risk," Hart said in a statement.

Timely Receipt of PCI in STEMI Up With Hospital Bypass Policy

May 01, 2018

Overall, 57.9 and 47.5% of patients, respectively, from states with hospital destination policies and states without hospital destination policies received primary PCI within their relevant guideline recommended time from first medical contact, after adjustment for patient- and state-level characteristics.

CCHD Newborn Screening May Detect Other Diseases

April 30, 2018

The researchers found that using the current AAP algorithm, 99.96% of infants passed screening. Of the infants who failed, 18 had an initial saturation of <90% and 16 did not attain a passing pulse oximetry level after 3 tests.