CHF And Arrhythmias

Acute Myocardial Infarction Can Affect Brain Inflammation

January 17, 2018

At 8 weeks, TSPO was concurrently up-regulated in remote cardiomyocytes without inflammatory cell infiltration.

Sauna Bathing Linked to Improvements in Cardiovascular Function

January 16, 2018

There was also a decrease in mean systolic blood pressure (BP) from 137 to 130mmHg and in diastolic BP from 82 to 75 mm Hg (both P<0.0001).

Wearable Patches May Provide Viable Heart Failure Tracking for Outpatients

January 16, 2018

The researchers found that a graph similarity score could assess heart failure patient state and correlates to clinical improvement in the 45 patients.

Number of Children, Age at First Birth May Contribute to Higher CVD Risk in Women

January 16, 2018

For CVD, adjusted hazard ratios of 1.16 and 2.30 were seen for hysterectomy without oophorectomy or with previous oophorectomy, respectively.

Thrombosis Risk Examined in Myeloproliferative Neoplasms

January 16, 2018

The researchers found that, compared with control participants, for patients with MPNs, the hazard ratios for arterial thrombosis were 3.0, 2.0, and 1.5 at 3 months, 1 year, and 5 years, respectively.

Effect of Combo Heart Failure Drug on Concomitant Furosemide Examined

By January 12, 2018

Sacubitril/valsartan is approved for the treatment of heart failure and reduced ejection fraction

Can Coronary CTA Identify Future Major Adverse Cardiovascular Events?

January 11, 2018

The researchers found that the rate of MACE was higher with the presence of high-risk plaque (6.4 versus 2.4%; hazard ratio, 2.73).

Long-Term Efficacy of Implantable Cardioverter-Defibrillators in Brugada

January 10, 2018

The researchers found that the vast majority of patients (92%) were symptomatic, including 29% presented with aborted sudden cardiac death and 63% with syncope.

Change in CVD Risk Factors Analyzed Following Bariatric Sx

January 10, 2018

The researchers found that increasing weight loss independently predicted normalization in dyslipidemia, elevated blood pressure, hyperinsulinemia, diabetes, and elevated high-sensitivity C-reactive protein.

Delta CHA<sub>2</sub>DS<sub>2</sub>-VASc May Forecast Stroke Likelihood More Accurately

January 09, 2018

The Delta CHA2DS2-VASc score significantly better predicted ischemic stroke compared to baseline or follow-up CHA2DS2-VASc scores

Are Patients With ITP at Increased Risk for Cardiovascular Disease?

January 09, 2018

The elevated risk of developing CVD in the ITP cohort (adjusted incidence rate ratio [IRR], 1.38) remained even after a sensitivity analysis which included only incident cases of ITP.

Experts Weigh In on the Best Diets for 2018

By January 03, 2018

DASH and the Mediterranean diet also tied for top stop in the 'Best Diets for Healthy Eating' category will DASH ranked number 1 for the 'Best Heart-Healthy Diets'.

Outcomes after left ventricular assist device implantation significantly worse for those with end-stage renal disease

January 03, 2018

Patients with end-stage renal disease (ESRD) have significantly worse survival outcomes following left ventricular assist device (LVAD) implantation compared to recipients without ESRD.

Using Statins to Prevent ASCVD: 5 Major Guidelines Compared

January 03, 2018

"Guidelines recommending that more persons use statins for primary prevention of ASCVD should prevent more events than guidelines recommending use by fewer persons," the authors write.

ACC: Guidelines for Optimizing Heart Failure Treatment

January 02, 2018

Consensus statement addresses 10 pivotal issues in heart failure with reduced ejection fraction

Safety of MRI for patients with legacy cardiac devices

January 01, 2018

Patients with a legacy pacemaker or cardioverter-defibrillator were followed after undergoing medically indicated magnetic resonance imaging (MRI) examinations, and no long-term clinically significant adverse effects were reported.

MRI Seems Safe for Patients With Legacy Pacemaker, ICD System

December 28, 2017

No long-term clinically significant adverse events reported among 1,509 patients

FDA Approves Oral Solution Formulation of Valsartan

By December 20, 2017

First approved oral liquid dosage form of the angiotensin II receptor blocker valsartan.

Impact of Switching Dual Antiplatelet Tx Examined After ACS

December 20, 2017

The researchers found that 47% of patients were classified as having low on-treatment platelet reactivity (LTPR; platelet reactivity index vasodilator-stimulated phosphoprotein ≤20%).

USPSTF Reviews Benefits and Harms of A-Fib Screening With ECG

December 19, 2017

Based on these findings, the USPSTF concludes that the potential harms of screening are equivalent to or exceed the potential benefits among asymptomatic adults at low risk for CVD events (D recommendation).

In Utero Exposure to ADHD Med Tied to Heart Defects

December 14, 2017

The researchers found that congenital malformations occurred in 35.0 per 1,000 infants not exposed to stimulants, compared with 45.9 and 45.4 per 1,000 infants for methylphenidate and amphetamines, respectively, in the U.S. data.

Hydroquinidine Examined for Reducing Serious Arrhythmic Events in SQTS

December 13, 2017

In comparison of life threatening arrhytmic events (LAE) for the 6 years before and after HQ, patients on HQ experienced a reduction in the rate of LAE (40 to 0%; P=0.03) and the number of LAE per patient.

Xarelto sNDA Submitted for Two New Vascular Indications

By December 11, 2017

For this group the risk of stroke was reduced by 42% (HR 0.58; 95% CI, 0.44-0.76; P<0.001), CV death by 22% (HR 0.78; 95% CI, 0.64-0.96; P=0.02) and heart attack by 14% (HR 0.86; 95% CI, 0.70-1.05; P=0.14).

Novel Furosemide Formulation Looks Promising for Outpatient HF Treatment

December 08, 2017

Urine output similar with furosemide administered subcutaneously versus intravenously

First PCSK9 Inhibitor Gets FDA Approval for MI, Stroke Prevention

By December 04, 2017

Repatha reduced the risk of heart attack by 27%, the risk of stroke by 21% and the risk of coronary revascularization by 22%.

Severe Hypoglycemia and Absolute CV Risk Examined in Community Setting

December 01, 2017

Following severe hypoglycemia, the 3-year cumulative incidence of mortality was 28.3%, and that of coronary heart disease was 10.8%.

FDA Approves KardiaBand for Apple Watch

By November 30, 2017

The first FDA-cleared medical device accessory for Apple Watch, KardiaBand can record an EKG in 30 seconds with just a touch of its integrated sensor.

Comparison of Oral Anticoagulants for Preventing Stroke in AF

By November 28, 2017

The greatest risk reduction of stroke or systemic embolism was seen with dabigatran 150mg twice daily (odds ratio [OR] 0.65, 95% CI: 0.52-0.81), followed by apixaban 5mg twice daily (OR 0.79, 95% CI: 0.66-0.94).

Obesity Tied to All-Cause Mortality in HF With Preserved Ejection Fraction

November 28, 2017

Data were included for 3,310 patients with HFpEF: 2,413 with abdominal obesity and 897 patients without abdominal obesity.

Coffee Consumption and Health Outcomes: An Umbrella Review of the Evidence

November 27, 2017

After adequate adjustment for smoking, harmful associations were mainly nullified, except in pregnancy, where there were correlations for high versus low/no consumption with low birth weight, preterm birth in the first and second trimester, and pregnancy loss.