CHANTIX
Generic Name for CHANTIX
Varenicline (as tartrate) 0.5mg, 1mg; tabs.
Legal Classification:
Rx
Pharmacological Class for CHANTIX
α4β2 nicotinic acetylcholine receptor partial agonist.
Manufacturer of CHANTIX
Pfizer Labs
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Indications for CHANTIX
Smoking cessation aid.
Adult dose for CHANTIX
Provide patients with counseling and educational support. Set a target "quit date". Begin therapy 1 week before target quit date. Take after eating with a glass of water. ≥18yrs: initially 0.5mg once daily for 3 days, then 0.5mg twice daily for 4 days, then 1mg twice daily. May reduce dose if intolerable nausea or other adverse effects occur. Treat for 12 weeks; may continue 12 more weeks if patient successfully stops smoking to further increase the likelihood of abstinence. Severe renal impairment: initially 0.5mg once daily; may titrate to max 0.5mg twice daily. End stage renal disease with hemodialysis: max 0.5mg once daily if tolerated. Reevaluate if abstinence is not achieved after 1st 12 weeks.
Children's dosing for CHANTIX
<18yrs: not recommended.
Warnings/Precautions for CHANTIX
Psychiatric disorders (monitor). Renal impairment. Pregnancy (Cat.C). Nursing mothers: not recommended.
Interactions for CHANTIX
Smoking cessation may affect metabolism of other drugs (eg, warfarin, theophylline, insulin). Increased adverse effects with nicotine replacement therapy.
Adverse Reactions for CHANTIX
Nausea, other GI effects (eg, constipation, flatulence, vomiting), sleep disturbance (eg, abnormal dreams, insomnia), headache; nicotine withdrawal symptoms (due to smoking cessation); serious neuropsychiatric symptoms (eg, behavioral changes, agitation, depression, suicidal ideation).
How is CHANTIX supplied?
Tabs—56
Starting Month PAK (0.5mg x 11 tabs + 1mg x 42 tabs)—1
Continuing Month PAK (1mg x 56 tabs)—1