CELEXA
Generic Name for CELEXA
Citalopram (as HBr) 10mg, 20mg+, 40mg+; tabs (+scored).
Legal Classification:
Rx
Pharmacological Class for CELEXA
SSRI.
Manufacturer of CELEXA
Forest Laboratories
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Indications for CELEXA
Depression.
Adult dose for CELEXA
Initially 20mg once daily; after ≥1 week may increase to 40mg once daily; may then increase to 60mg once daily for non-responders or partial responders. Elderly or hepatic impairment: 20mg once daily; may increase to 40mg once daily for nonresponders.
Children's dosing for CELEXA
Not recommended.
Also:
Contraindications for CELEXA
During or within 14 days of MAOIs; do not start an MAOI during or within 14 days of citalopram.
Warnings/Precautions for CELEXA
History of seizures or mania/hypomania. Hepatic or severe renal impairment (CrCl <20mL/min). Altered metabolic or hemodynamic states. Recent MI. Unstable heart disease. Suicidal tendencies. ECT. Avoid abrupt cessation. Reevaluate periodically. Write ℞ for smallest practical amount. Labor & delivery. Pregnancy (Cat.C) (avoid 3rd trimester; see literature for effects on neonate). Nursing mothers: not recommended.
Interactions for CELEXA
MAOIs: see Contraindications. Do not give with escitalopram. May be potentiated by cimetidine, potent inhibitors of CYP3A4 (eg, azole antifungals, macrolides), or potent inhibitors of CYP2C19 (eg, omeprazole). May be antagonized by carbamazepine. Caution with tricyclic antidepressants, lithium, other centrally-acting drugs, oral anticoagulants, NSAIDs, aspirin. Alcohol: not recommended. Increases metoprolol levels. Weakness, hyperreflexia, incoordination with 5-HT1B/1D agonists (eg, sumatriptan).
Adverse Reactions for CELEXA
GI upset, dry mouth, somnolence, insomnia, increased sweating, anorexia, rhinitis, sexual dysfunction, agitation, fatigue, arthralgia, myalgia, hyponatremia, SIADH, abnormal bleeding.
How is CELEXA supplied?
Tabs—100
Soln—240mL
Related Disease:
Depression