Cefoxitin Injection

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Generic Name for Cefoxitin Injection

Cefoxitin sodium 1g, 2g; for IV inj; sodium content 2.3mEq/g.

Legal Classification:

Rx

Pharmacological Class for Cefoxitin Injection

Cephalosporin.

Manufacturer of Cefoxitin Injection

Various generic manufacturers

Indications for Cefoxitin Injection

Susceptible bacterial septicemia, lower respiratory or urinary tract, skin and skin structure, bone and joint, gynecologic, intraabdominal infections. Surgical prophylaxis.

Adult dose for Cefoxitin Injection

Usually 1–2g every 6–8 hrs. Uncomplicated: 1g every 6–8 hrs. Moderately severe to severe: 1g every 4 hrs or 2g every 6–8 hrs. Max 2g every 4 hrs or 3g every 6 hrs. Prophylaxis: see literature.

Children's dosing for Cefoxitin Injection

<3months: not recommended. ≥3months: 80-160mg/kg per day in 4–6 equal divided doses; max 12g/day. Prophylaxis: see literature.

Warnings/Precautions for Cefoxitin Injection

Penicillin or other allergy. Renal impairment (CrCl <50mL/min), reduce dose: see literature. GI disease (esp. colitis). Pregnancy (Cat.B). Nursing mothers.

Interactions for Cefoxitin Injection

Aminoglycosides may potentiate nephrotoxicity. Potentiated by probenecid. May cause false (+) Clinitest. May interfere with creatinine tests.

Adverse Reactions for Cefoxitin Injection

Local reactions, rash, pruritus, drug fever, GI upset, anaphylaxis, blood dyscrasias, elevated liver enzymes.

How is Cefoxitin Injection supplied?

Contact supplier.

Related Disease:

Infections, bacterial~systemic antiinfectives

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