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CAVERJECT
Erectile dysfunction
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Drug Name:

CAVERJECT Rx

Generic Name and Formulations:
Alprostadil 5mcg, 10mcg, 20mcg, 40mcg; per vial; pwd for intracavernous inj after reconstitution.

Company:
Pfizer Inc.

e-Prescribe this drug via Surescripts


Therapeutic Use:

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Indications for CAVERJECT:

Treatment and diagnosis of erectile dysfunction.

Adult Dose for CAVERJECT:

Inject into the dorso-lateral aspect of the proximal third of penis, avoid visible veins; rotate inj side and site. Determine optimum dose in office. If no response, may give 2nd dose after 1 hr; if partial response occurs, wait 24 hrs before next dose. Vasculogenic, psychogenic, or mixed etiology: initially 2.5mcg; if partial response, may give 2nd dose of 5mcg; may increase in increments of 5–10mcg until desired response. If no response to 1st dose, may give 2nd dose of 7.5mcg; may increase in increments of 5–10mcg until desired response. Neurogenic etiology: initially 1.25mcg; may give 2nd dose of 2.5mcg, and 3rd dose of 5mcg; may increase in increments of 5mcg until desired response. Usual max: 60mcg and 3 inj/week; allow at least 24 hrs between doses. Reduce dose if erection lasts over 1 hr.

Children's Dose for CAVERJECT:

Not recommended; see Contraindications.

Pharmacological Class:

Prostaglandin.

Contraindications:

Predisposition to priapism. Anatomical penile deformation. Penile implants. Patients for whom sexual activity is inadvisable or contraindicated. Women. Children. Newborns.

Warnings/Precautions:

Treat priapism immediately. Patient must not adjust dose on own. Reevaluate every 3 months. Discontinue if penile fibrosis occurs.

Interactions:

Concomitant vasoactive agents: not recommended. Caution with anticoagulants.

Adverse Reactions:

Priapism, prolonged erection, penile pain or fibrosis, inj site hematoma or ecchymosis, prostatic disorder, penile rash or edema, other local effects, hypertension, headache, increased risk of blood-borne diseases, others.

How Supplied:

Vials (10, 20, or 40mcg)—6
Kits (5, 10, or 20mcg vials + diluent syringes)—6
Ampules (10, 20, or 40mcg)—5
Caverject impulse (10 or 20mcg dual chamber syringe systems + supplies)—2

CAVERJECT

  • 20mcg vials (Qty:6)
  • appx. price $352.00
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