CATAFLAM Rx

Indications for CATAFLAM:

Osteoarthritis. Rheumatoid arthritis. Ankylosing spondylitis.

Adult Dose for CATAFLAM:

Osteoarthritis: 50mg 2–3 times daily. Rheumatoid arthritis: 50mg 3–4 times daily. Ankylosing spondylitis: 25mg 4 times daily, may add 25mg at bedtime.

Children's Dose for CATAFLAM:

Not recommended.

Pharmacological Class:

NSAID (benzeneacetic acid deriv.).

Contraindications:

Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Advanced renal disease: not recommended. Peptic ulcer. GI bleeding. Monitor AST/ALT within 4 weeks and then periodically; also blood, hepatic, and renal function in chronic use. Edema. Cardiac failure. Hypertension. Hepatic porphyria. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin, methotrexate, cyclosporine, lithium toxicity. Antagonizes diuretics. May increase serum potassium level with K⁺-sparing diuretics. Avoid aspirin. Monitor oral anticoagulants, insulin and sulfonylureas. Increased risk of GI bleed with alcohol.

Adverse Reactions:

Peptic ulcer, GI bleeding, elevated AST/ALT, abdominal discomfort, constipation, diarrhea, indigestion, nausea, abdominal distention, headache, dizziness, fluid retention, rash (discontinue if occurs), pruritus, tinnitus. See literature re: risk of cardiovascular events.

How Supplied:

Tabs—100

Indications for CATAFLAM:

Dysmenorrhea.

Adult Dose for CATAFLAM:

50mg 3 times daily; may give 100mg initially.

Children's Dose for CATAFLAM:

Not applicable.

Pharmacological Class:

NSAID (benzeneacetic acid deriv.).

Contraindications:

Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Advanced renal disease: not recommended. Peptic ulcer. GI bleeding. Monitor AST/ALT within 4 weeks and then periodically; also blood, hepatic, and renal function in chronic use. Edema. Cardiac failure. Hypertension. Hepatic porphyria. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin, methotrexate, cyclosporine, lithium toxicity. Antagonizes diuretics. May increase serum potassium level with K⁺-sparing diuretics. Avoid aspirin. Monitor oral anticoagulants, insulin and sulfonylureas. Increased risk of GI bleed with alcohol.

Adverse Reactions:

Peptic ulcer, GI bleeding, elevated AST/ALT, abdominal discomfort, constipation, diarrhea, indigestion, nausea, abdominal distention, headache, dizziness, fluid retention, rash (discontinue if occurs), pruritus, tinnitus. See literature re: risk of cardiovascular events.

How Supplied:

Tabs—100

Indications for CATAFLAM:

Pain.

Adult Dose for CATAFLAM:

50mg 3 times daily; may give 100mg initially.

Children's Dose for CATAFLAM:

Not recommended.

Pharmacological Class:

NSAID (benzeneacetic acid deriv.).

Contraindications:

Aspirin allergy. Late pregnancy. Coronary artery bypass graft surgery.

Warnings/Precautions:

Advanced renal disease: not recommended. Peptic ulcer. GI bleeding. Monitor AST/ALT within 4 weeks and then periodically; also blood, hepatic, and renal function in chronic use. Edema. Cardiac failure. Hypertension. Hepatic porphyria. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Digoxin, methotrexate, cyclosporine, lithium toxicity. Antagonizes diuretics. May increase serum potassium level with K⁺-sparing diuretics. Avoid aspirin. Monitor oral anticoagulants, insulin and sulfonylureas. Increased risk of GI bleed with alcohol.

Adverse Reactions:

Peptic ulcer, GI bleeding, elevated AST/ALT, abdominal discomfort, constipation, diarrhea, indigestion, nausea, abdominal distention, headache, dizziness, fluid retention, rash (discontinue if occurs), pruritus, tinnitus. See literature re: risk of cardiovascular events.

How Supplied:

Tabs—100