CARNITOR INJECTION Rx

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CARNITOR INJECTION

Inborn errors of metabolism
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Generic Name and Formulations:

Levocarnitine 200mg/mL; soln for IV bolus inj or infusion; preservative-free.

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Indications for CARNITOR INJECTION:

Secondary carnitine deficiency. Carnitine deficiency in end stage renal disease (ESRD) patients undergoing dialysis.

Adults and Children:

Secondary carnitine deficiency: 50mg/kg IV as slow (2–3 minutes) bolus inj or by infusion; usual max 300mg/kg. May give loading dose in severe metabolic crisis: see literature. ESRD: initially 10–20mg/kg dry body weight as slow (2–3 minutes) IV bolus inj into venous return line after each dialysis session; adjust dose based on trough levocarnitine levels.

Warnings/Precautions:

Obtain baseline carnitine level; monitor blood chemistry, carnitine levels, vital signs, clinical condition. Seizure disorders. Renal insufficiency (oral forms). Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

Concomitant warfarin: monitor INR.

See Also:

CARNITOR

CARNITOR ORAL SOLUTION

CARNITOR SF

Adverse Reactions:

GI upset/pain, body odor, seizures; inj: hypercalcemia, local reactions.

How Supplied:

Tabs—90; Oral soln—4oz; Inj amps or vials (single-dose 5mL)—5