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Cardiovascular System Resource Center

Welcome to the MPR Cardiovascular System Resource Center, where you will find everything you need to make informed clinical decisions.

Drug Monographs

News

Palpitations Predict Future Atrial Fibrillation

Palpitations, hypertension, and body mass index (BMI) are predictive of future atrial fibrillation (AF) in both men and women.
 

Short-Term Smoke Exposure Impairs Endothelial Function

Short-term exposure to low levels of secondhand smoke (SHS) results in a concentration-dependent decrease in endothelial function.
 

Recurrent HTN Seen for Half of Women With HTN in Pregnancy

About half of women who experience a hypertensive disorder of pregnancy and late-preterm delivery develop a hypertensive disorder in a subsequent pregnancy, although few have delivery before 37 weeks in the subsequent pregnancy.
 

SAFETY ALERT: Risk of Cardiovascular Death with Zithromax

The FDA is notifying healthcare professionals of a new study reporting a small increase in cardiovascular death, and in the risk of death from any cause, in patients treated with a 5-day course of azithromycin (Zithromax; Pfizer) compared to persons treated with amoxicillin, ciprofloxacin, or no drug.
 

Causality Link Between HDL Cholesterol, MI Challenged

Genetic mechanisms that are associated with high plasma levels of high-density lipoprotein (HDL) cholesterol do not reduce the risk of myocardial infarction (MI), adding question to causality of link.
 

Statins Benefit Those at Low Risk for Vascular Events

Reduction of low-density lipoprotein (LDL) cholesterol with statins is associated with a decrease in major vascular events, even for individuals with a five-year risk of <10%.
 

Retinal Vessel Diameter Linked to Heart Disease, Hypertension

Baseline retinal vessel diameter is an independent predictor of incident hypertension, lower extremity arterial disease (LEAD), and any cardiovascular disease (CVD) at six years in African-American patients with type 1 diabetes mellitus.
 

Azithromycin Tied to Increased Risk of Cardiovascular Mortality

Azithromycin treatment is associated with an increased risk of cardiovascular and all-cause mortality.
 

Coffee Drinking Linked to Lower Mortality Risk

Coffee drinking is associated with a lower risk of death from most major causes except cancer.
 

CDC: 35th Report on the Health of the Nation Published

The 35th report on the health status of the United States in 2011 has been published online May 16 by the US Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).
 

New Drugs

DUTOPROL

5/21/2012

Pharmacological Class: Cardioselective β1-blocker + diuretic.
Active Ingredient(s): Metoprolol succinate extended-release, hydrochlorothiazide; 25/12.5mg, 50/12.5mg, 100/12.5mg; tablets.
Indication: Hypertension.
 

NEXTERONE

12/23/2011

Pharmacological Class: Class III antiarrhythmic.
Active Ingredient(s): Amiodarone HCl 1.5mg/mL, 1.8mg/mL; premixed in dextrose; soln for IV infusion.
Indication: Initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation (VF) and hemodynamically unstable ventricular tachycardia (VT) in patients refractory to other therapy or when oral form is not feasible.
 

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