Cardiovascular Disease

In Utero Exposure to ADHD Med Tied to Heart Defects

December 14, 2017

The researchers found that congenital malformations occurred in 35.0 per 1,000 infants not exposed to stimulants, compared with 45.9 and 45.4 per 1,000 infants for methylphenidate and amphetamines, respectively, in the U.S. data.

Hydroquinidine Examined for Reducing Serious Arrhythmic Events in SQTS

December 13, 2017

In comparison of life threatening arrhytmic events (LAE) for the 6 years before and after HQ, patients on HQ experienced a reduction in the rate of LAE (40 to 0%; P=0.03) and the number of LAE per patient.

Many Without Cardiovascular Risk Factors Have Atherosclerosis

December 13, 2017

LDL-C independently associated with the presence and extent of atherosclerosis

Efficacy of Edoxaban Investigated for CA-Linked Venous Thromboembolism

December 13, 2017

The researchers found that a primary-outcome event occurred in 12.8 and 13.5% of patients in the edoxaban and dalteparin groups, respectively (HR, 0.97; 95% CI, 0.70 to 1.36; P=0.006 for noninferiority; P= 0.87 for superiority).

Xarelto sNDA Submitted for Two New Vascular Indications

By December 11, 2017

For this group the risk of stroke was reduced by 42% (HR 0.58; 95% CI, 0.44-0.76; P<0.001), CV death by 22% (HR 0.78; 95% CI, 0.64-0.96; P=0.02) and heart attack by 14% (HR 0.86; 95% CI, 0.70-1.05; P=0.14).

Iron Deficiency Treatment in a Heart Failure Patient

December 11, 2017

A women with a 30-year history of hypertension, hyperlipidemia and an 8-year history of systolic dysfunction is hospitalized for congestion following a 5-day river cruise.

RAS Inhibitor Use May Cut Risk of MI in Rheumatoid Arthritis Patients

By December 08, 2017

The use of angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) was associated with a reduced risk of myocardial infarction (MI) among patients with rheumatoid arthritis (RA).

Novel Furosemide Formulation Looks Promising for Outpatient HF Treatment

December 08, 2017

Urine output similar with furosemide administered subcutaneously versus intravenously

Triple Therapy Linked to Mortality Rate in CAD With GI Bleeding

December 06, 2017

Increased mortality at 90 days in patients with lower gastrointestinal bleeding, coronary artery disease

Should Antithrombotics Be Stopped Before Wide-Awake CTR Surgery?

December 05, 2017

Ninety-three of the 99 patients taking AT medication continued their normal regimen through surgery and were included in the analysis.

First PCSK9 Inhibitor Gets FDA Approval for MI, Stroke Prevention

By December 04, 2017

Repatha reduced the risk of heart attack by 27%, the risk of stroke by 21% and the risk of coronary revascularization by 22%.

Patient Admitted Eleven Times for Hypertriglyceridemia-Induced Pancreatitis

By December 01, 2017

The patient was was admitted eleven times over seven years for hypertriglyceridemia-induced pancreatitis.

Warfarin Stability Examined After Transfer to Dose Administration Aids

December 01, 2017

"Repackaging of warfarin sodium tablets into DAAs does not affect the chemical stability," the authors wrote.

Severe Hypoglycemia and Absolute CV Risk Examined in Community Setting

December 01, 2017

Following severe hypoglycemia, the 3-year cumulative incidence of mortality was 28.3%, and that of coronary heart disease was 10.8%.

FDA Approves KardiaBand for Apple Watch

By November 30, 2017

The first FDA-cleared medical device accessory for Apple Watch, KardiaBand can record an EKG in 30 seconds with just a touch of its integrated sensor.

Combination Hypertension Treatments

November 30, 2017

A comparative list of combination antihypertensive medications used for the treatment for hypertension.

Klor-Con Powder for Oral Solution Now Available

By November 28, 2017

Klor-Con Powder for oral solution is available as packets that contain 1.5g of potassium chloride (supplying potassium 20mEq and chloride 20mEq) in 30- and 100-count cartons.

Comparison of Oral Anticoagulants for Preventing Stroke in AF

By November 28, 2017

The greatest risk reduction of stroke or systemic embolism was seen with dabigatran 150mg twice daily (odds ratio [OR] 0.65, 95% CI: 0.52-0.81), followed by apixaban 5mg twice daily (OR 0.79, 95% CI: 0.66-0.94).

Obesity Tied to All-Cause Mortality in HF With Preserved Ejection Fraction

November 28, 2017

Data were included for 3,310 patients with HFpEF: 2,413 with abdominal obesity and 897 patients without abdominal obesity.

Coffee Consumption and Health Outcomes: An Umbrella Review of the Evidence

November 27, 2017

After adequate adjustment for smoking, harmful associations were mainly nullified, except in pregnancy, where there were correlations for high versus low/no consumption with low birth weight, preterm birth in the first and second trimester, and pregnancy loss.

Higher &#946;-Blocker Dose May Benefit CHF Patients With Diabetes

November 21, 2017

Effect is larger in chronic heart failure patients with diabetes than CHF patients without diabetes

Impact of Oral Anticoagulants on Renal Outcomes Compared

November 21, 2017

Compared with warfarin, dabigatran and rivaroxaban linked to lower risk of adverse renal outcomes

Tekturna Oral Pellets Approved to Treat Hypertension in Adults and Children

By November 20, 2017

Tekturna is indicated for the treatment of hypertension in adults and children 6 years of age and older, to lower blood pressure.

Does Allopurinol Benefit Patients With Cardiac Syndrome X?

November 17, 2017

No improvement in exercise capacity, coronary or peripheral endothelial function after six weeks

Antiarrhythmic Agent Recalled Due to Presence of Particulate Matter

By November 16, 2017

Nexterone is a prescription antiarrhythmic agent indicated for initiation of treatment and prophylaxis of frequently recurring ventricular fibrillation and hemodynamically unstable ventricular tachycardia in patients refractory to other therapy.

FDA: Gout Drug Linked to Increased Risk of Heart-Related Death

By November 15, 2017

The FDA required the Uloric drug manufacturer, Takeda Pharmaceuticals, to conduct this safety study when the medicine was approved in 2009.

Empagliflozin Cuts CVD Risk in Patients With Type 2 Diabetes, PAD

By November 15, 2017

At study start, 21% of the more than 7,000 EMPA-REG OUTCOME trial participants had existing peripheral artery disease.

Does Noninvasive Testing Improve Outcomes in Patients With Acute Chest Pain?

November 15, 2017

Noninvasive testing with CCTA or stress testing also leads to more radiation exposure, greater cost

Evolocumab Found to Benefit Patients With PAD, History of MI

By November 15, 2017

Analysis showed that patients with more recent heart attacks experienced substantial risk reductions.

Methamphetamine Heart Failure May Present New Phenotype

November 15, 2017

"Clinicians are seeing more heart failure with meth use, suggesting heart failure due to methamphetamine use could be a new epidemic," said lead author, Marin Nishimura, MD, in a statement.