Cardiovascular Disease

Major Cardiac Event Risks Among Minorities Examined Following PCI

October 19, 2017

But women and minorities have higher adjusted risk of death/MI after PCI with everolimus-eluting stent

Expert Consensus Published for Mitral Regurgitation Management

October 19, 2017

"This expert consensus decision pathway provides the clinician with additional tools to improve the care of MR patients," the authors write. "It can serve as a guide to patient assessment and individualized decision making."

Appropriate Use Criteria Created for Heart Condition

October 18, 2017

SAVR or TAVR appropriate for most patients with symptomatic AS at intermediate or high surgical risk.

Safety of Direct Oral Anticoagulant in VTE Examined

October 18, 2017

Researchers conducted a retrospective matched cohort study to examine the safety of DOAC versus warfarin use for treatment of venous thromboembolism. Direct Oral Anticoagulant VTE

PPI Use and First-Time Stroke, MI: What's the Link?

October 18, 2017

After adjustment for age, sex, comorbidities, and concomitant medications, the rates of ischemic stroke and MI were significantly increased with current PPI exposure (hazard ratios, 1.13 and 1.31).

Thrombosis Risks Assessed for Bioresorbable Scaffolds vs. Metallic Stents

October 17, 2017

The safety and efficacy of everolimus-eluting bioresorbable vascular scaffolds was evaluated compared to everolimus-eluting metallic stents using data from 7 randomized trials and 38 observational studies.

Thromboembolic Disorder Treatments: Without DVT/PE

October 16, 2017

A comparative medication chart of thromboembolic disorder treatments in patients without DVT/PE.

Hypertension Treatments: ARBs

October 16, 2017

A comparative list of Angiotensin II Receptor Blockers (ARBs) monotherapy and combination therapy for the treatment of hypertension.

Hypertension Treatments: Oral CCBs

October 16, 2017

Oral calcium channel blockers (CCBs) for the treatment of hypertension including benzothiazepines, dihydropyridines, and diphenylalkylamines.

Hypertension Treatments: ACE Inhibitors

October 16, 2017

A comparative list of Angiotensin-Converting Enzyme (ACE) Inhibitors monotherapy and combination therapy for the treatment of hypertension.

Combination Hypertension Treatments

October 16, 2017

A comparative list of combination antihypertensive medications used for the treatment for hypertension.

Liraglutide for Weight Loss Not Associated With Excess Cardiovascular Risk

October 13, 2017

The researchers found that with liraglutide (3.0mg), 8 participants had positively adjudicated cardiovascular events (1.54 events/1,000 person-years), compared to 10 participants in the comparators group (3.65 events/1000 person-years).

CMR Imaging Role Assessed in Myocarditis Prognosis

October 13, 2017

The researchers found that 98 patients experienced a major adverse cardiovascular event (MACE) at a median follow-up of 4.7 years.

Merck Decides to Put the Brakes on CETP Inhibitor Anacetrapib

By October 13, 2017

The decision follows a review of the clinical profile and discussions with external experts

Better Risk Factor Modification Strategies Needed for Optimal Stroke Prevention

October 12, 2017

Increases in prevalence of hypertension, diabetes, dyslipidemia, smoking, and drug abuse in AIS

Sauna Bathing May Have Blood Pressure Benefits

By September 29, 2017

Compared to those who reported taking 1 sauna per week - using Cox regression analysis that adjusted for age, smoking, body mass index, and systolic blood pressure - the hazard ratio for incident hypertension in those reporting 2-3 and 4-7 sauna sessions was 0.76 (95% CI; 0.57 - 1.02) and 0.54 (95% CI; 0.32-0.91), respectively.

PCSK9i Prescription Approval, Abandonment Rate in First Year of Availability

September 28, 2017

The researchers found that 20.8% of patients given a prescription received approval on the first day and that 47.2% ever received approval.

Intravenous Umbilical Cord Stem Cell Tx Assessed in HFrEF Patients

September 27, 2017

The researchers found that, compared with bone marrow-derived mesenchymal stem cells, UC-MSCs in vitro displayed a 55-fold increase in the expression of hepatocyte growth factor.

Post-Op Outcomes for Individualized vs. Standard Blood Pressure Tx

September 27, 2017

The researchers found that the primary outcome event occurred in 38.1 and 51.7% of patients assigned to the individualized treatment group and standard treatment strategy group, respectively.

Warfarin Dosing Based on Genotype May Reduce Adverse Events

September 27, 2017

Overall, 808 and 789 patients in the genotype-guided and clinically-guided groups, respectively, completed the trial.

Low-Dose Oxygen Assessed in Post-Acute Stroke Care

September 27, 2017

The researchers found that no subgroup benefited from oxygen.

Risk of CV Events Up After Discontinuing Long-Term Low-Dose Aspirin

September 26, 2017

There was a higher rate of cardiovascular events among patients who discontinued aspirin versus those who continued.

Post-Food Consumption Cardiac Arrest May Indicate Rare Heart Condition

By September 22, 2017

Researchers concluded that vagal stimulus-dependent SCA after eating a large bite of food may be the first symptom of BS.

Bleomycin Sclerotherapy Efficacy Tested in Vascular Malformations

September 22, 2017

There was significant improvement in all lesions of capillary malformation with nodular change and lymphatic malformation, as well as in 82.4% of lesions of venous malformation.

Increased Med Use Over Time Seen in Older Patients of All BMI Classes

By September 22, 2017

Researchers aimed to determine whether the rise in prescription drug use over time varied by age and obesity status.

Portable DVT Prevention Device Now Available

By September 21, 2017

As well as preventing DVT the company indicates that PlasmFlow can be used to enhance blood circulation, reduce post-operative pain and swelling, aid in the treatment of stasis dermatitis, venous stasis ulcers, arterial and diabetic leg ulcers, chronic venous insufficiently and reduce of edema in the lower limbs.

Depression Found to Be Independently Associated with Recurrent Chest Pain

By September 20, 2017

On multivariable regression models, depression was a significant independent predictor of 30-day chest pain recurrence after adjustment.

Entresto Ups Physical, Social Activity in Systolic Heart Failure Patients

By September 19, 2017

In addition, improvements in physical and social activities were observed at the pre-specified 8 months and continued through 3 years.

Effects of Anagliptin vs. Alogliptin on Lipid Profile of T2D Patients

September 19, 2017

The researchers found that there was no significant difference in percent change in LDL-C level between the 2 groups at 24 weeks.

Beta-Blocker Use Post-Heart Attack Called Into Question

By September 19, 2017

They found that patients who only took the ACE inhibitor, or an angiotensin receptor blocker, and statin were no more likely to die than those who took all 3 prescribed treatments.