Cardiovascular Disease

Heart Meds Recalled After Discovery of Possible Carcinogenic Impurity

By July 16, 2018

As valsartan is used to treat various cardiovascular conditions including heart failure and hypertension, patients should continue to take their medications until they have a replacement product,

Asthma Control and Atrial Fibrillation Risk: Is There a Link?

July 13, 2018

Dose-response association seen between levels of asthma control and risk of atrial fibrillation

More Youth Classified With HTN Using New 2017 AAP Guidelines

July 13, 2018

The researchers found that there was a decrease in the prevalence of hypertension during this time, using both the new guidelines (from 7.7 to 4.2%) and former guidelines (from 3.2 to 1.5%).

Multivitamin/Mineral Supplementation and CVD Outcomes: Is There a Link?

July 12, 2018

The researchers found that there was no correlation between MVM supplementation and CVD mortality, CHD mortality, stroke mortality, or stoke incidence 1.02, 0.95, and 0.98.

Evidence Lacking for ABI for PAD Screen in Asymptomatic, Says USPSTF

July 12, 2018

"At this time, there is not enough evidence to recommend for or against using the ABI as a screening tool," Task Force member Seth Landefeld, MD, said in a statement.

USPSTF: Recommendation on Using Nontraditional CVD Risk Factors

July 12, 2018

Based on these findings, the Task Force concluded that the evidence is currently inadequate for assessing the balance of benefits and harms of adding these nontraditional risk factors to the traditional risk assessment of CVD.

Fresenius Kabi Adds Additional Strengths to Adenosine Product Line

By July 11, 2018

Adenosine Injection, a pharmacologic stress agent, is indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately.

Safety of Direct Oral Anticoagulants Versus Warfarin Investigated

July 11, 2018

Compared with warfarin, apixaban was correlated with reduced risk of major bleeding and intracranial bleeding (adjusted hazard ratios, 0.66 and 0.4, respectively) and dabigatran was correlated with reduced risk of intracranial bleeding (adjusted hazard ratio, 0.45) among patients with atrial fibrillation.

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

By July 10, 2018

For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin regimen in adults with recent-onset type 1 diabetes (age range: 18 to 45 years).

Transfeminine Persons Have Increased VTE Incidence

July 10, 2018

The researchers found that the incidence of VTE was higher for transfeminine participants, with 2- and 8-year risk differences of 4.1 and 16.7 per 1,000 persons, respectively.

Hydralazine-Induced Hepatotoxicity Described in Case Report

By July 09, 2018

Symptoms in patients with short latency include fever, rash, and eosinophilia.

Blister Packs for Several Meds Recalled Due to Risk of Harm to Children

By July 09, 2018

The recall affects approximately 470,000 units that include drugs packaged with 3 to 10 tablets per blister card. The blister packs were developed for use in hospitals, however some were sent to retail pharmacies and were likely dispensed for in-home use.

High-Risk <i>APOL1</i> Not Tied to CVD, Stroke in Older Black Women

July 09, 2018

Carriers of high-risk APOL1 variants had increased incidence of hospitalized heart failure with preserved ejection fraction (HFpEF) compared with low-risk carriers after a mean of 11 years; no differences were seen for other outcomes.

Atypical Antipsychotic Use and CV Events in Youth: What's the Link?

By July 06, 2018

The retrospective cohort study involved a search of Medicaid claims of pediatric patients aged 5 to 20 years who were initiated on atypical antipsychotic medications.

Increase in Prevalence of Pediatric Hypertension With New Definitions

July 06, 2018

Incorporation of new pediatric definitions increased prevalence of hypertension in high-risk youth

Marriage May Protect Against Cardiovascular Disease

July 05, 2018

Association seen between marital status and risk, prognosis of coronary heart disease or stroke

Gastroprotective Effects of PPIs, H2RAs Compared in Patients on DAPT

By July 03, 2018

For this study, researchers searched several large databases (from 1980 to 2016) for randomized, controlled trials (RCTs) that compared clinical outcomes in patients on DAPT taking PPIs or H2RAs.

Coffee Drinking Found to Lower Risk of All-Cause Mortality

July 03, 2018

Similar findings across type of coffee, quantity, type of death, and caffeine metabolism score

Weight Loss Linked to Reversal of Atrial Fibrillation Progression

July 03, 2018

Increased weight loss with risk factor management associated with greater atrial fibrillation freedom

Nitric Oxide Cuts Kidney Injury After Long Cardiac Surgery

July 02, 2018

Reduced kidney injury, better kidney function seen after prolonged cardiopulmonary bypass

Genetic Risk, Lifestyle Predict CVD, Diabetes Independently

June 28, 2018

A total of 339,003 unrelated individuals of white British descent with available genotype and matching genetic data from the UK Biobank cohort study were included in the study.

Idaho Pharmacists Able to Prescribe Meds for Several Conditions on July 1

By June 27, 2018

The new rule allows pharmacists to prescribe medications for cold sores, seasonal influenza, strep throat, and urinary tract infections, as well as statins for patients with diabetes.

Clotting Time in Transfemoral PCI Linked to Bleeding Risk

June 27, 2018

Researchers related maximal ACT to the risk of major bleeding in 14,634 patients undergoing TR or TF PCI with unfractionated heparin monotherapy.

Hypertension: Beta-Blocker Pharmacokinetics

June 26, 2018

Beta-blocker pharmacokinetics comparison chart for hypertension.

Rivaroxaban Use in Older Patients: Does Age Influence Safety, Efficacy?

By June 25, 2018

Data from large Phase 3 studies showed that treatment with rivaroxaban was found to be safe and effective in older patients.

Empagliflozin, Liraglutide Reduce Cardiovascular Mortality Risk

June 25, 2018

Investigators conducted a meta-analysis to compare the efficacy of SGLT2i, DPP-4i, and GLP-1 agonists for reducing cardiovascular outcomes.

Clinical Significance of Genetic Variations in CYP2D6 Investigated in HF Patients

By June 21, 2018

According to HF guidelines, beta-blockers must be titrated to a specific target dose in order to obtain their morbidity and mortality benefit in HF patients.

Varicella Vaccination and Pediatric Arterial Ischemic Stroke: Is There a Link?

By June 20, 2018

The study authors reported that the rate of AIS in the 12 months following vaccination was 7.8 per 100,000 person-years at risk (95% CI: 4.8, 10.9) in patients who received the vaccine versus 6.8 (95% CI: 1.3, 12.2) in those who did not.

Should Physicians Treat Family and Friends? Three Experts Weigh In

By June 19, 2018

Although all of the guidelines acknowledge that there are emergent situations in which providing care for a family member or friend is not only permissible but also essential, other situations are frowned upon.

Increased Risk of MI, Ischemic Stroke After COPD Exacerbation

June 19, 2018

Greater risks were seen following a severe exacerbation (incidence rate ratios, 2.58 and 1.97 for myocardial infarction and ischemic stroke, respectivley) than after a moderate exacerbation (incidence rate ratios, 1.58 and 1.45, respectively).