CAPOZIDE 25/15

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Generic Name for CAPOZIDE 25/15

Captopril 25mg, hydrochlorothiazide 15mg; scored tabs.

Legal Classification:

Rx

Pharmacological Class for CAPOZIDE 25/15

ACE inhibitor + diuretic.

Manufacturer of CAPOZIDE 25/15

Par Pharmaceutical, Inc.

Indications for CAPOZIDE 25/15

Hypertension.

Adult dose for CAPOZIDE 25/15

Take 1 hr before meals. As initial therapy: one 25/15 tab daily; adjust at 6 wk intervals. Previously titrated: use same doses as individual components. Usual max 150mg captopril, 50mg hydrochlorothiazide daily.

Children's dosing for CAPOZIDE 25/15

See literature.

Also:

Contraindications for CAPOZIDE 25/15

Anuria. Sulfonamide allergy. History of ACEI-associated angioedema. Pregnancy (Cat.D in 2nd and 3rd trimesters).

Warnings/Precautions for CAPOZIDE 25/15

Renal or hepatic dysfunction. Salt/volume depletion. CHF. Dialysis (esp. high-flux membrane). Aortic stenosis. Diabetes. Gout. Asthma. Postsympathectomy. Surgery. Monitor electrolytes. Monitor WBCs and renal function in renal and collagen vascular disease. Discontinue if neutropenia, agranulocytosis, angioedema or laryngeal edema occurs. Pregnancy (Cat.C in 1st trimester). Nursing mothers: not recommended.

Interactions for CAPOZIDE 25/15

Potentiated by antihypertensives. Potentiates tubocurarine. May antagonize sulfonylureas, oral anticoagulants, uricosurics. May be antagonized by NSAIDs, sympathomimetics. May increase digitalis, lithium, insulin, diazoxide toxicity. Hyperkalemia with potassium-sparing diuretics and supplements. Hypokalemia with ACTH, corticosteroids. Orthostatic hypotension may be increased by alcohol, CNS depressants. May interfere with parathyroid, urinary acetone tests.

Adverse Reactions for CAPOZIDE 25/15

Neutropenia, agranulocytosis, proteinuria, nephrotic syndrome, orthostatic hypotension, fluid or electrolyte imbalance, rash, GI upset, dysgeusia, hyperglycemia, hyperuricemia, dizziness, headache, cough, pruritus, angioedema, tachycardia, chest pain, jaundice, blurred vision.

How is CAPOZIDE 25/15 supplied?

Tabs—100

Related Disease:

Hypertension

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