Butalbital/Acetaminophen/Caffeine Rx

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Migraine and headache
Only 4 drugs may be compared at once

Generic Name and Formulations:

Butalbital 50mg, acetaminophen 325mg, caffeine 40mg; tabs; caps.

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Indications for Butalbital/Acetaminophen/Caffeine:

Tension (or muscle contraction) headache.


1–2 tabs or caps every 4hrs as needed; max 6 daily.


Not established.




Drug abusers. Severe hepatic or renal impairment (monitor). Acute abdominal conditions. Discontinue if serious skin rash or hypersensitivity reactions occur. Elderly. Debilitated. Pregnancy (Cat.C). Nursing mothers: not recommended.

Pharmacological Class:

Barbiturate + analgesic.


May potentiate effects of alcohol, general anesthetics, tranquilizers, sedative-hypnotics, or other CNS depressants or narcotic analgesics; avoid. MAOIs may enhance CNS effects of butalbital. May cause false (+) urine test for 5-hydroxyindoleacetic acid.

Adverse Reactions:

Drowsiness, lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, abdominal pain, intoxicated feeling; hepatotoxicity (APAP doses >4g/day); rare: serious skin reactions, hypersensitivity.


Formerly known under the brand name Esgic.

How Supplied:

Contact supplier.

Butalbital/Acetaminophen/Caffeine 50mg/325mg/40mg tablets (Qty:5)

appx. price $29.00