BPH Surgery Complication Rates Underestimated

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PARIS—Complication rates after surgery for benign prostatic hyperplasia (BPH) are higher in real clinical practice than in clinical trials, according to data presented at the 27th Annual Congress of the European Association of Urology.

French researchers led by Jean-Nicolas Cornu, MD, of Tenon Hospital in Paris, noted that data about BPH surgery complications are based mainly on clinical trials with stringent outcome criteria. Based on a study of all men who had BPH surgery in France from 2004 to 2007 (262,898 patients), however, they concluded that the rate of BPH surgery complications has been underestimated and patients should be advised that subsequent surgery after initial BPH surgical management is not rare.

After a median follow-up of 1.51 years, 4.38% of patients had a new surgery for BPH. The retreatment rate was higher for the 228,262 men who underwent transurethral resection of the prostate (TURP) than for the 34,635 men who had an open prostatectomy (4.77% vs. 1.92%).

The study showed that 9,152 patients had a clot removal intervention (3.4% after TURP and 3.7% after open prostatectomy). Over the study period, 420 men had a surgical intervention for urinary incontinence after TURP (0.18%) compared with 31 men after open prostatectomy (0.09%). In addition, 2.7% and 1.3% of TURP and open prostatectomy patients, respectively, had surgery for urethral stenosis.

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