BLA Submitted for Albiglutide for Type 2 Diabetes

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GlaxoSmithKline announced a regulatory submission to the FDA for albiglutide, an investigational once-weekly treatment for adult patients with type 2 diabetes. 

Albiglutide, a GLP-1 receptor agonist, is designed for subcutaneous dosing.  GLP-1 is a peptide that is normally secreted from the gastrointestinal tract during a meal which in turn helps release insulin to control blood sugar elevations after eating.  In people with type 2 diabetes, GLP-1 secretion in response to a meal is reduced or absent.   GLP-1 is rapidly degraded while albiglutide has been developed to have a longer duration of action by being comprised of two copies of modified human GLP-1 fused in series to human albumin.

For more information call (888) 825-5249 or visit www.gsk.com

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