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BILTRICIDE

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Generic Name for BILTRICIDE

Praziquantel 600mg; scored tabs.

Legal Classification:

Pharmacological Class for BILTRICIDE

Trematodicide.

Manufacturer of BILTRICIDE

Merck & Co., Inc.

Indications for BILTRICIDE

For the treatment of infections due to: all species of schistosoma, and infections due to the liver flukes, Clonorchis sinensis/Opisthorchis viverrini.

Adults and Children:

Swallow whole with water during meals. <4yrs: not recommended. ≥4yrs: Schistosomiasis: 20mg/kg 3 times daily as a one day treatment, at intervals ≥4hrs and ≤6hrs. Clonorchiasis, opisthorchiasis: 25mg/kg 3 times daily as a one day treatment, at intervals ≥4hrs and ≤6hrs.

Contraindications for BILTRICIDE

Ocular cysticercosis. Concomitant strong CYP450 inducers (eg, rifampin).

Warnings/Precautions for BILTRICIDE

Moderate to severe hepatic impairment. History of epilepsy. Cerebral cysticercosis: hospitalize patient for duration of treatment. Monitor patients with cardiac irregularities. Pregnancy (Cat.B). Nursing mothers: not recommended and during subsequent 72hrs.

Interactions for BILTRICIDE

See Contraindications. Discontinue rifampin 4 weeks before giving praziquantel; may be restarted one day after completing praziquantel treatment. Potentiated by CYP450 inhibitors (eg, cimetidine, ketoconazole, itraconazole, erythromycin), grapefruit juice. Antagonized by CYP450 inducers (eg, phenytoin, phenobarbital, carbamazepine, dexamethasone), chloroquine.

Adverse Reactions for BILTRICIDE

Malaise, headache, dizziness, abdominal discomfort, nausea, fever; rare: urticaria.

How is BILTRICIDE supplied?

Tabs—6

Related Disease:

Clonorchiasis

Opisthorchiasis

Schistosomiasis

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