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BIAXIN

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Generic Name for BIAXIN

Clarithromycin 250mg, 500mg; tabs.

Legal Classification:

Pharmacological Class for BIAXIN

Macrolide.

Manufacturer of BIAXIN

Abbott Laboratories

Indications for BIAXIN

Mild to moderate susceptible pharyngitis/tonsillitis, acute bacterial exacerbation of chronic bronchitis, community-acquired pneumonia, acute maxillary sinusitis, acute otitis media, uncomplicated skin and skin structure infections. Disseminated M. intracellulare. Treatment (with other antimycobacterials) and prophylaxis of disseminated Mycobacterium avium complex (MAC).

Adult dose for BIAXIN

Pharyngitis/tonsillitis: 250mg every 12 hours for 10 days. Bronchitis: 250mg–500mg every 12 hours for 7–14 days. CAP, skin and skin structures: 250mg every 12 hours for 7–14 days. Sinusitis: 500mg every 12 hours for 14 days. MAC: 500mg every 12 hours continue indefinitely if improvement occurs. CrCl <30mL/min: ½ dose or double dosing interval.

Children's dosing for BIAXIN

<6 months: not recommended. Otitis media, pharyngitis/tonsillitis, pneumonia, sinusitis, skin and skin structures: 7.5mg/kg every 12 hours for 10 days. MAC (see literature): 7.5mg/kg every 12 hours; max 500mg twice daily, continue indefinitely if improvement occurs. CrCl <30mL/min: ½ dose or double dosing interval.

Also:

BIAXIN ORAL SUSPENSION

BIAXIN XL

Contraindications for BIAXIN

Concomitant cisapride, pimozide.

Precautions for BIAXIN

Severe renal impairment. Pregnancy (Cat.C): usually not recommended. Nursing mothers.

Interactions for BIAXIN

See Contraindications. May potentiate theophylline, carbamazepine, omeprazole, phenytoin, digoxin, warfarin, ergot alkaloids, triazolam, cyclosporine, hexobarbital, tacrolimus, alfentanil, disopyramide, bromocriptine, valproate, rifabutin, statins; monitor these and others metabolized by CYP450. May affect zidovudine levels. With ritonavir in renal impairment: reduce clarithromycin dose (see literature).

Adverse Reactions for BIAXIN

GI upset, abnormal taste, headache, rash, increased BUN.

How is BIAXIN supplied?

XL tabs, tabs—60
Biaxin XL-Pac (14 x 500mg XL tabs)—4
Susp—50mL, 100mL

Related Disease:

Infections, bacterial~systemic antiinfectives

Pneumonia

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