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AVODART

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Generic Name for AVODART

Dutasteride 0.5mg; caps.

Legal Classification:

Pharmacological Class for AVODART

Type I and II 5α-reductase inhibitor.

Manufacturer of AVODART

GlaxoSmithKline Pharmaceuticals

Indications for AVODART

BPH, as monotherapy to improve symptoms and reduce risks of acute urinary retention and need for prostate surgery; or in combination with tamsulosin.

Adult dose for AVODART

Swallow whole. Monotherapy: 0.5mg once daily. Combination therapy: 0.5mg once daily with tamsulosin 0.4mg once daily.

Children's dosing for AVODART

Not applicable.

Contraindications for AVODART

Not for use in children or women. Pregnant women and those of childbearing potential should avoid handling capsules.

Warnings/Precautions for AVODART

Not for use in preventing prostate cancer. Increased risk of high-grade prostate cancer. Monitor prostate specific antigen (PSA) values (establish new baseline PSA after 3–6 months of treatment); double PSA levels to compare with normal values. Rule out prostate cancer and other urological disorders prior to treatment. Hepatic dysfunction. Avoid donating blood until at least six months after last dose.

Interactions for AVODART

May be potentiated by CYP3A4/5 inhibitors (eg, ritonavir, ketoconazole, verapamil, diltiazem, cimetidine, troleandomycin, ciprofloxacin); caution.

Adverse Reactions for AVODART

Impotence, decreased libido, ejaculation disorder, gynecomastia, dizziness (with tamsulosin).

How is AVODART supplied?

Caps—30, 90

Related Disease:

BPH/urinary retention {BPH/urinary retention}

Dutasteride Doesn't Alter Anabolic Effects of Testosterone

March 07, 2012

Men receiving testosterone supplementation who also receive dutasteride, which blocks the conversion of testosterone to its potent metabolite 5α-dihydrotestosterone (DHT), do not experience a significant difference in changes in muscle-related measures or sexual function compared to men receiving testosterone without dutasteride.

Male Pattern Baldness Linked to Prostate Symptoms

February 24, 2012

Early-onset of male pattern baldness (androgenetic alopecia [AGA]) may be a marker of male urinary symptoms associated with an enlarged prostate.

Coronary Artery Disease Linked to Risk of Prostate Cancer

February 13, 2012

A significant correlation between coronary artery disease (CAD) and prostate cancer (PCa) has been found among men participating in a prostate drug trial.

Cialis Approved to Treat Benign Prostatic Hyperplasia (BPH)

October 07, 2011

Cialis (tadalafil; Lilly) tablets for once daily use have been approved for the treatment of men who have both erectile dysfunction and the signs and symptoms of benign prostatic hyperplasia (BPH).

Generic Uroxatral Tablets

September 05, 2011

Mylan has begun shipment of Alfuzosin HCl extended-release tablets, the generic version of Uroxatral (sanofi aventis), a treatment for signs and symptoms of benign prostatic hyperplasia.

CARDURA

Urogenital System > Benign prostatic hyperplasia/urinary retention

Doxazosin (as mesylate) 1mg, 2mg, 4mg, 8mg; scored tabs.

CIALIS

Urogenital System > Benign prostatic hyperplasia/urinary retention

Tadalafil 2.5mg, 5mg, 10mg, 20mg; tabs.

FLOMAX

Urogenital System > Benign prostatic hyperplasia/urinary retention

Tamsulosin HCl 0.4mg; caps.

HYTRIN

Urogenital System > Benign prostatic hyperplasia/urinary retention

Terazosin (as HCl) 1mg, 2mg, 5mg, 10mg; caps.

URECHOLINE

Urogenital System > Benign prostatic hyperplasia/urinary retention

Bethanechol chloride 5mg, 10mg, 25mg, 50mg; scored tabs.

ASTELIN

Respiratory Tract > Rhinitis/rhinorrhea (intranasal products)

Adverse reactions updated.

Updated: 5/8/2012

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Dermatological Disorders > Pruritus and dry skin

Monograph added.

Updated: 4/25/2012

ATRAPRO DERMAL SPRAY

Dermatological Disorders > Pressure/neuropathic ulcers

Monograph added.

Updated: 4/24/2012

B-NEXA

Nutrition > Vitamins/minerals/supplements

Monograph added.

Updated: 4/30/2012

BYDUREON

Endocrine System > Diabetes

Monograph added.

Updated: 4/20/2012

Urogenital System > Benign prostatic hyperplasia/urinary retention

Two classes of drugs are approved for the treatment of BPH: 5α-reductase inhibitors and α-blockers. The 5α-reductase inhibitors ...
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