≥18yrs: 2 caplets with a glass of water. Max 2 caplets/24hours.
<18yrs: not recommended.
Analgesic + salicylate.
NSAID allergy. Varicella, vaccinia in children and teenagers. 3rd trimester of pregnancy. Concomitant other acetaminophen products.
Persistent or unresponsive headache. History of asthma or peptic ulcer. Impaired hepatic or renal function. Hypertension. Bleeding disorders. Erosive gastritis. Diabetes. Gout. Elderly (>60yrs). Pregnancy. Nursing mothers: not recommended.
See Contraindications. May potentiate anticoagulants, hypoglycemics, methotrexate. Urinary alkalinizers, antacids, corticosteroids may increase aspirin excretion. May antagonize uricosurics, spironolactone. Increased risk of liver toxicity and/or GI bleed with alcohol.
Gastric upset, prolonged bleeding time, urticaria, anaphylaxis, nervousness, irritability, insomnia, tachycardia; overdosage: salicylism, hepatoxicity.