Bacterial Infections

Antibiotics May Reduce Infection Risk Post-Colorectal CA Surgery

October 19, 2017

The researchers found that patients who received oral antibiotics and MBP had a lower overall SSI rate than those who received MBP only (8 versus 27%; P=0.03).

Combo Antibiotic Gets Priority Review for New Pneumonia Indication

By October 13, 2017

Avycaz is a combination antibiotic consisting of ceftazidime, a cephalosporin, and avibactam, a beta-lactamase inhibitor.

Leprosy Vaccine Candidate to Be Tested in Humans

By October 12, 2017

Leprosy (also known as Hansen's disease) is caused by the Mycobacterium leprae bacteria and results in disfiguration of the skin and mucous membranes as well as incurable nerve damage.

Statin Use May Decrease Risk of Community-Acquired Staph Infection

October 11, 2017

The researchers found that compared with nonusers, current statin users experienced markedly decreased risk of CA-SAB (adjusted odds ratio [OR], 0.73; 95% confidence interval, 0.63 to 0.84).

Test Helps Clinicians Select Appropriate Tx for Suspected Wound Infections

By October 05, 2017

Using a simple swab from the infection site, DxWound uses a special transport buffer that preserves the wound microbiome during transit.

Antibiotic Combo Tx May Up Risk of Acute Kidney Injury in Children

October 03, 2017

Risk of AKI in hospitalized children higher than with IV vancomycin, other antipseudomonal -lactam

CDC: Sexually Transmitted Diseases Hit 'Record High' in U.S.

By September 26, 2017

The majority of syphilis infections are seen particularly in gay, bisexual, and other men who have sex with men (MSM), of which half are also diagnosed with HIV.

Linhaliq NDA Granted Priority Review

By September 25, 2017

Linhaliq was previously granted Qualified Infectious Disease Product (QIDP) Designation and Fast Track designation for NCFBE with lung infections with P. aeruginosa.

AAP Explores Major Infectious Disease Risk Factors in Team Sports

September 25, 2017

The researchers found that skin-to-skin contact with athletes who have active skin infections, environmental exposures, and physical trauma are major risk factors for infection, as well as sharing of equipment and contact with contaminated fomites.

Hair Regrowth in Alopecia Patients After Fecal Transplant for Recurrent CDI

By September 22, 2017

These 2 cases suggests that fecal transplants can have a profound immunological response not only limited to intestinal effects, say the authros.

Prophylactic Antibiotic Course Post C-Section May Reduce SSI Rate

September 20, 2017

The researchers found that the overall rate of SSI was 10.9% in the cohort. Overall, 6.4 and 15.4% of women in the cephalexin-metronidazole and placebo groups, respectively, were diagnosed with SSI (relative risk, 0.41).

Phase 3 Results of Novel CABP Treatment Announced

By September 18, 2017

A second 'LEAP 2' trial is currently in the midst of enrolling patients and expected to have topline results in the spring of 2018.

Baxdela Yields High Response Against Fluoroquinolone-Non-Susceptible MRSA

By September 18, 2017

Baxdela also yielded high response rates against S. aureus isolates with mutations in the Quinolone Resistance Determining Region (QRDR) in 98.8% of cases. QRDR mutations lower the fluoroquinolone binding and increase resistance.

AAP Publish First Guidance on Tattooing, Piercing for Adolescents

By September 18, 2017

These can occur from contamination of the inks or diluents used for tattooing.

Single-Dose Oral Therapy for Bacterial Vaginosis Gets Approval

By September 18, 2017

The approval was based on two randomized, placebo-controlled studies which evaluated the efficacy of Solosec in the treatment of bacterial vaginosis.

Antibiotic Class Linked to Increased Risk of GI Perforation

By September 18, 2017

The researchers compared a cohort of 17,510 individuals diagnosed with GI perforation to a matched group of 1,751,000 controls.

Plans Stepped Up to Curb San Diego Hepatitis Outbreak

By September 12, 2017

Streets will be power-washed by crews using bleach-spiked water to clean what, in a letter the County called a "fecally contaminated environment".

Current Diagnostic Tools Failing to ID Bacterial Infections in Infants

September 12, 2017

Sensitivities were low for common complete blood cell count thresholds: white blood cell count <5,000/µL, 10%; white blood cell count ≥15,000/µL, 27%; absolute neutrophil count ≥10,000/µL, 18%; and platelets <100 × 10³/µL, 7%.

CDC: Pet Store Chain Source of Multistate <i>Campylobacter</i> Outbreak

September 12, 2017

Nine people have been hospitalized but no deaths have been reported.

Bacterial Transmission from Guinea Pigs Linked to Three Cases of CAP

September 08, 2017

Three cases of community-acquired pneumonia reported after exposure to ill guinea pigs

Race May Play Role in Antibiotic Rx Trends for Pediatric ARTI

September 06, 2017

The researchers found that 2.6% of the PED encounters for viral ARTIs resulted in patient receipt of antibiotics, including 4.3, 1.9, 2.6, and 2.9% of non-Hispanic white, non-Hispanic black, Hispanic, and other non-Hispanic children, respectively.

Could a Change in Boarding Practices Cut the Spread of Infection on Planes?

By September 01, 2017

"It turns out that procedures that are generally good at getting people onto a plane very fast are also very bad at preventing infection," said Associate Professor of Computer Science Ashok Srinivasan.

Recall: Glass Found in Antibiotic Vial

By August 31, 2017

The products have Lot #632153A and the National Drug Code of the recalled lot is 0409-6531-02.

FDA Approves Unique Antibiotic Combo Drug Vabomere

By August 30, 2017

Vabomere is a combination antibiotic that includes meropenem, a penem antibacterial, and vaborbactam, a non-suicidal beta-lactamase inhibitor.

Penicillin Safety in Those with Allergy History But Negative Skin Test

By August 24, 2017

The authors reported that zero patients developed an immediate hypersensitivity reaction during these courses of administration.

Pediatric Septic Shock Mortality Predictor Biomarker Improves

August 23, 2017

PERSEVERE-XP had an area under the receiver operating characteristic curve (AUC) of 0.90 (95% confidence interval, 0.85 to 0.95) for differentiating between survivors and non-survivors in the derivation cohort. The AUC was 0.96 (95% confidence interval, 0.91 to 1.0) in the test cohort.

Celiac Disease Linked to Increased Risk of Pneumococcal Infection

By August 15, 2017

After adjusting for socioeconomic index, diabetes, level of education, sex and age, an increased risk of pneumococcal infection among celiac disease patients was noted.

Efficacy of Killed Whole-Cell Oral Cholera Vaccine Examined

August 14, 2017

During the 2 years after vaccination the 2-dose efficacy estimates were similar, with estimates of 56 and 59% in the first and second year, respectively.

NDA Submitted for Non-Cystic Fibrosis Bronchiectasis Treatment

By August 11, 2017

Linhaliq (previously known as 'Pulmaquin') consists of a mixture of liposome encapsulated and unencapsulated ciprofloxacin. Linhaliq has previously been granted Orphan Drug status for the management of bronchiectasis.

Gastroenteritis Hospitalizations Down with Rotavirus Vaccine Introduction

August 11, 2017

The researchers found that 16% of the 1,253,951 AGE-related hospitalizations among children aged <5 years were coded as a rotavirus-related hospitalization.