Bacterial Infections

Multidrug-Resistant <i>Campylobacter</i> Outbreak Linked to Pet Store Puppies

By September 20, 2018

Of the 149 puppies investigated, 142 (95%) received ≥1 courses of antibiotics, raising concern that antibiotic use may have led to development of resistance.

Multivalent Pneumococcal Conjugate Vaccine Gets Breakthrough Tx Designation

By September 20, 2018

The Breakthrough designation follows an FDA examination of results from a Phase 2 randomized, double-blind trial which evaluated the safety and immunogenicity of the treatment in adults aged 60 to 64 years.

Final CDC Update on <i>Salmonella</i> Linked to Backyard Poultry

September 17, 2018

People who became ill said they got live chicks and ducklings from relatives and from businesses such as feed supply stores, websites, and hatcheries, the CDC said.

Positive Results for Zerbaxa in Phase 3 Study of Ventilated HABP, VABP Patients

By September 11, 2018

The full findings from the study will be presented at a future scientific conference; Merck plans to include the data in a supplemental New Drug Application for Zerbaxa which will be submitted to the Food and Drug Administration.

Patient's Black Hairy Tongue Linked to Antibiotic Therapy

By September 10, 2018

The case involved a 55-year-old female patient who had been admitted to the hospital after suffering injuries from a car accident.

NICU Antibiotic Use Rates Declined From 2013 to 2016

September 10, 2018

There was no correlation between the 2016 AUR and either proven infection or necrotizing enterocolitis. However, there was an association between the 2016 regional NICU AUR and surgical volume, mortality rate, and average length of stay

Gaps in Prevention, Management of Tickborne Diseases Identified

September 06, 2018

Diagnostic and surveillance limitations and lack of treatment options, vaccines hamper efforts

130 Now Sickened by <i>Salmonella</i>-Tainted Honey Smacks Cereal

September 06, 2018

The cereal under recall includes Honey Smacks 15.3 oz. size with the UPC code of 3800039103 and a Best if Used by Date of JUN 14, 2018, through JUN 14, 2019.

CDC: Increase in Rate of STDs for Fourth Consecutive Year in US

September 05, 2018

Nearly 2.3 million total cases of chlamydia, gonorrhea, syphilis diagnosed in the United States in 2017

USPSTF Reaffirms Screening for Syphilis in Pregnancy

September 04, 2018

Congenital syphilis can be prevented with effective treatment with antibiotics, significantly decreasing adverse pregnancy outcomes, with small associated harms.

FDA: Cases of Rare Gangrene of Genital Area Tied to Diabetes Drug Class

By August 30, 2018

The infection developed within several months of the patients starting SGLT2 therapy and the drug was discontinued in most cases. All patients required surgery and there was 1 reported death.

Partial Oral Abx Non-Inferior in Endocarditis on Left Side of Heart

August 30, 2018

he researchers found that the primary composite outcome of all-cause mortality, unplanned cardiac surgery, embolic events, or relapse of bacteremia with the primary pathogen occurred in 12.1 and 9% of patients in the intravenously and orally treated groups, respectively.

Physicians Lack Knowledge About Serogroup MenB Vaccination

August 28, 2018

Vaccination was recommended by 91% of those who discussed often or always and by 11% of those who never or rarely discussed.

Xerava Approved for the Treatment of Complicated Intra-Abdominal Infections

By August 28, 2018

Eravacycline was well-tolerated in clinical trials and achieved high cure rates in patients with Gram-negative pathogens (including resistant strains).

CDC: Brucellosis in Dogs Remains a Public Health Risk

August 17, 2018

The researchers found that brucellosis in dogs remains endemic to many parts of the world and will probably remain a threat to human health and animal welfare unless stronger intervention measures are implemented.

Prevalence of Antimicrobial-Contraindicated Drug Combo Prescribing Examined

By August 16, 2018

Researchers performed a cross-sectional study that included multiple year pooled data (2003 to 2011) from the National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey (NHAMCS Outpatient Department).

Iclaprim Gets Priority Review for Acute Bacterial Skin/Skin Structure Infections

By August 15, 2018

Clinical data has indicated that the drug exhibits a low propensity for resistance development as well as a favorable tolerability profile.

Completing Sepsis Bundle Within an Hour Cuts Pediatric Mortality

August 14, 2018

Completing the entire bundle within 1 hour was associated with a lower risk of in-hospital mortality (odds ratio [OR], 0.59; 95% confidence interval [CI], 0.38 to 0.93; P=.02).

Omadacycline Gets FDA Committee Nod for Skin Infections, Pneumonia

By August 09, 2018

The Committee's recommendation was based on data from the omadacycline global development program that included nearly 2000 adults in three Phase 3 studies.

FDA Panel Votes on Therapy for Nontuberculous Mycobacterial Lung Disease

By August 09, 2018

The recommendation was supported by materials developed from the ALIS New Drug Application (NDA), which included data from the CONVERT study.

New Tick Species Spreading in the United States

August 09, 2018

The ticks can reproduce rapidly and suck so much blood from a young animal that it dies, The Times reported.

Ciprofloxacin May Up Likelihood of Aortic Dissection, Rupture

August 06, 2018

Increased susceptibility observed in mouse model of sporadic aortic aneurysm and dissection

Some Bacteria Now More Tolerant of Alcohol-Based Sanitizers

August 06, 2018

Enterococci bacteria surviving exposure for longer periods of time

Dog's Saliva Caused Bacterial Infection Leading to Amputations

August 03, 2018

Doctors diagnosed Manteufel with a rare blood infection caused by Capnocytophaga canimorsus, which is commonly found in the saliva of most healthy dogs and is usually not harmful to humans, the Post reported.

CDC: <i>Salmonella</i>-Tainted Melon Outbreak Appears to Be Over

July 27, 2018

No deaths have been reported. Illnesses have been reported in Arkansas (1), Florida (1), Illinois (7), Indiana (14), Kentucky (1), Michigan (39), Missouri (11), Ohio (2), and Tennessee (1).

FDA Clears Smartphone-Enabled Urinalysis Kit for Home Use

By July 25, 2018

The kit works in tandem with existing smartphone cameras and a dedicated app.

<i>Salmonella</i> Spurs Recall of Ritz Crackers

July 24, 2018

No illnesses associated with the recalled Ritz products have been reported, according to the New Jersey-based company.

Zemdri Now Available for the Treatment of Complicated UTI, Pyelonephritis

By July 20, 2018

Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

Availability of Generic Antivirals for Hepatitis B Increasing

July 20, 2018

Researchers examined the patent and licensing status of entecavir and tenofovir using the Medicines Patent Pool MedsPaL database.

Lyme-Bearing Ticks More Widespread in US Than Thought

July 20, 2018

"Disease-carrying ticks were detected in 83 counties where they'd never been found before."People should be aware of ticks and tick-borne disease, even when they may think there's not a recorded incidence of a tick in a county."