AVODART Rx

Indications for AVODART:

BPH, as monotherapy to improve symptoms and reduce risks of acute urinary retention and need for prostate surgery; or in combination with tamsulosin.

Adult Dose for AVODART:

Swallow whole. Monotherapy: 0.5mg once daily. Combination therapy: 0.5mg once daily with tamsulosin 0.4mg once daily.

Children's Dose for AVODART:

Not applicable.

Pharmacological Class:

Type I and II 5 alpha-reductase inhibitor.

Contraindications:

Not for use in children or women. Pregnant women and those of childbearing potential should avoid handling capsules.

Warnings/Precautions:

Not for use in preventing prostate cancer. Increased risk of high-grade prostate cancer. Monitor prostate specific antigen (PSA) values (establish new baseline PSA after 3–6 months of treatment); double PSA levels to compare with normal values. Rule out prostate cancer and other urological disorders prior to treatment. Hepatic dysfunction. Avoid donating blood until at least six months after last dose.

Interactions:

May be potentiated by CYP3A4/5 inhibitors (eg, ritonavir, ketoconazole, verapamil, diltiazem, cimetidine, troleandomycin, ciprofloxacin); caution.

Adverse Reactions:

Impotence, decreased libido, ejaculation disorder, gynecomastia, dizziness (with tamsulosin).

How Supplied:

Caps—30, 90