Generic Name and Formulations:
Mometasone furoate 110mcg/inh, 220mcg/inh; pwd for oral inhalation, metered-dose inhaler.
Company:
Merck & Co., Inc.
Maintenance treatment of asthma as prophylactic therapy.
Previously on bronchodilators alone or inhaled corticosteroids: initially 220mcg once in the PM; max 440mcg daily (either as 220mcg twice daily or 440mcg once daily). Previously on oral corticosteroids (wean gradually): initially 440mcg twice daily; max 880mcg daily. Rinse mouth after use.
<4yrs: not recommended. 4–11yrs: 110mcg once in the PM; max 110mcg daily. Rinse mouth after use.
Steroid.
Not for treatment of acute attacks. Milk protein allergy.
Maintain regular regimen. Infections. If exposed to chickenpox or measles, consider anti-infective prophylactic therapy. Monitor intraocular pressure; bone mineral density if other osteoporosis risk factors exist; and for growth suppression in children; hypercorticism and HPA axis suppression (if occurs, discontinue gradually). If adrenal insufficiency exists following systemic corticosteroids, replacement with inhaled steroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude). Prescribe a short-acting, inhaled β2-agonist for acute symptoms; monitor for increased need. Pregnancy (Cat. C). Nursing mothers.
Caution with potent CYP3A4 inhibitors (eg, ketoconazole).
Headache, respiratory or other infection, oral candidiasis, dysmenorrhea, musculoskeletal pain, GI upset, allergic rhinitis, sinus congestion, sinusitis, depression, fatigue, pain, bronchospasm (discontinue if occurs). Children: fever, bruise.
Twisthaler 110mcg (30 inh)—1; 220mcg (30 inh, 60 inh, 120 inh)—1