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ARICEPT

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Generic Name for ARICEPT

Donepezil HCl 5mg, 10mg, 23mg; tabs.

Legal Classification:

Pharmacological Class for ARICEPT

Reversible acetylcholinesterase inhibitor (piperidine deriv).

Manufacturer of ARICEPT

Eisai Pharmaceuticals

Indications for ARICEPT

Alzheimer's dementia.

Adult dose for ARICEPT

Tabs: Swallow whole with water. ODT: dissolve on tongue, then drink water. Mild-moderate: Initially 5mg daily at bedtime, may increase to 10mg daily after 4–6 weeks; usual dose: 5mg or 10mg once daily. Moderate-severe: initially 10mg daily at bedtime, may increase to 23mg daily after 3 months; usual dose: 10mg or 23mg once daily.

Children's dosing for ARICEPT

Not applicable.

Also:

ARICEPT ODT

Warnings/Precautions for ARICEPT

Cardiac conduction conditions. Peptic ulcer. Monitor for GI bleeding. Seizures. Asthma or COPD. GI or GU obstruction. Body weight <55kg. Pregnancy (Cat.C). Nursing mothers.

Interactions for ARICEPT

Drugs that affect CYP2D6 and CYP3A4 may affect rate of elimination. Antagonizes anticholinergics. May potentiate succinylcholine-type muscle relaxants, other cholinesterase inhibitors, cholinergic agonists (eg, bethanecol). Concomitant NSAIDs may increase risk of GI bleed.

Adverse Reactions for ARICEPT

GI upset, insomnia, muscle cramps, fatigue, anorexia, weight loss (esp. using 23mg/day dose).

How is ARICEPT supplied?

Tabs 5mg, 10mg—30, 90, 1000; 23mg—30, 90; ODT—30

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