Some vaccines—rubella, HepA, RAB-HDC, VAR, ZOS, and one form of IPV (the Poliovax contained in Pentacel)—are grown in cultured human embryo fibroblast cell lines (WI-38 or MRC-5) because these are the only cells that replicate the viruses in high enough titer for mass production (the rubella vaccine strain itself was originally isolated from an aborted fetus with intrauterine infection).
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