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Generic Name and Formulations:

Methylphenidate HCl 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg; ext-rel caps.

Select therapeutic use:

Indications for APTENSIO XR:

Attention deficit hyperactivity disorder.

Adults and Children:

Individualize. Swallow whole or may open capsule and sprinkle contents onto applesauce. <6yrs: not established. ≥6yrs: 10mg once daily in the AM. May titrate dose in weekly increments of 10mg/day. Max 60mg/day. Discontinue if no improvement after dose adjustment over a 1-month period.


During or within 14 days of MAOIs.


Abuse potential (monitor). Increased risk of sudden death, stroke, and MI; assess for presence of cardiac disease before initiating. Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, and other cardiac problems. Pre-existing psychotic disorder. Bipolar disorder. Screen for risk factors in developing manic episode prior to initiating. Consider discontinuing if new psychotic/manic symptoms occur. Peripheral vasculopathy including Raynaud's phenomenon; monitor for digital changes. Monitor growth (esp. children), BP, HR. Reduce dose or discontinue if paradoxical worsening of symptoms occurs. Write ℞ for smallest practical amount. Reevaluate periodically. Pregnancy. Nursing mothers: monitor infants.

Pharmacological Class:

CNS stimulant.


See Contraindications. Hypertensive crisis with concomitant MAOIs. Risk of serotonin syndrome with serotonergic drugs.

Adverse Reactions:

Abdominal pain, decreased appetite, headache, insomnia; hypertension, tachycardia, priapism.

How Supplied:

Ext-rel caps—90

APTENSIO XR 10mg capsules (Qty:30)

appx. price $251.00