Anaphylaxis

Auvi-Q 0.1mg Auto-Injector Approved for Infants, Small Children

By November 20, 2017

Auvi-Q 0.1mg is the first epinephrine auto-injector specifically designed for the treatment of life-threatening allergic reactions, including anaphylaxis, in infants and small children weighing 16.5 to 33 pounds.

Researchers Develop Portable Food Allergen-Detection System

By September 07, 2017

Most products were accurate to their stated label, however most products did contain at least 1 unspecified antigen, for instance, "brand of nut-free cookies contained gluten, whereas a gluten-free brand contained a peanut allergen," the authors write.

Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study

By August 17, 2017

Results found that 4 children initially treated with PPOIT and 6 treated with placebo had allergic reactions to peanut intake, none experience prophylaxis.

FDA: Severe Hypersensitivity, Death Following Curcumin Injection

By August 04, 2017

In March and May 2017, two patients given intravenous (IV) infusions of curcumin emulsion compounded with polyethylene glycol (PEG) 40 castor oil reported having immediate hypersensitivity reactions.

Epinephrine Auto-Injector for Infants, Small Children Gets Priority Review

By July 27, 2017

The company has indicated that if the new auto-injector is approved they expect it to be available for patients in the first half of 2018.

Delayed Anaphylaxis Treatment Often Occurs in Children

July 13, 2017

The researchers found that 36.3% of the children received epinephrine before arrival at the emergency department or UCC.

Vitamin D Supplementation Assessed for Preventing Allergic Diseases

July 12, 2017

The researchers found that based on very low certainty in the body of evidence across examined studies, vitamin D supplementation may not reduce the risk of developing allergic diseases.

Recommendations Issued in Response to Hymenoptera Venom Extract Shortage

July 10, 2017

Facing expected season-long shortage, doctors asked to urge patients to carry epinephrine auto-injectors

Symjepi Approved for Emergency Anaphylaxis Treatment

By June 16, 2017

Symjepi should only be injected into the anterolateral aspect of the thigh; injection into other areas such as the buttocks or the hands and feet may result in adverse effects and may also not provide effective treatment of anaphylaxis.

Quality of Life May Drop for Some During Oral Immunotherapy

May 30, 2017

Patients with better QOL at baseline, might deteriorate after therapy

Delayed Allergic Reaction Triggered by Meat Linked to Tick Bites

By May 24, 2017

States in the Midwest and South appear to have the highest prevalence of both alpha-gal allergy and rickettsial diseases transmitted by the Lone Star tick or Amblyomma americanum.

Case: Exercise-Induced Anaphylaxis After Shrimp Consumption

May 17, 2017

FDEIA due to shrimp consumption reported in 18-year-old with specific IgE antibodies against 43 kDa

Are Expired EpiPens Still Effective?

May 10, 2017

Patients at a community clinic in San Diego were asked to bring in unused, expired EpiPens so they could be examined.

Potential Defect Prompts EpiPen Recall

By April 03, 2017

The recall affects both the EpiPen Auto-Injector 0.15mg and 0.3mg strengths and the product was distributed by Mylan Specialty between December 2015 and July 2016.

Refractory Ulcerative Colitis in a Patient with NSAID Hypersensitivity

By March 22, 2017

The patient, a 33-year old woman with a history of drug hypersensitivity to NSAIDs and aspirin, presented for management of her chronic UC with mesalamine.

AAP: Epinephrine Auto-Injector, Action Plan Crucial for Anaphylaxis Management

February 14, 2017

This clinical report from the American Academy of Pediatrics is an update on their 2007 clinical report.

FDA: Life-Threatening Allergic Reactions Linked to Skin Antiseptic

By February 02, 2017

Reactions can occur within minutes of exposure.

Voice-Guided Epinephrine Auto-Injector Soon to Be Available

By January 19, 2017

Kaléo announced that Auvi-Q (epinephrine injection) Auto-injector will be available in pharmacies beginning February 14th.

Authorized Generic for EpiPen Coming Next Week

By December 16, 2016

Mylan announced the launch of Epinephrine Injection Auto-Injector, the authorized generic for EpiPen Auto-Injector.

Study on Anaphylaxis Incidence Shows Low Epinephrine Auto-Injector Prescribing Rates

By December 12, 2016

Findings from a study published in the Annals of Allergy, Asthma & Immunology suggest the ongoing difficulty in diagnosing anaphylaxis as evident by the low prescribing rates of epinephrine auto-injector in cases of anaphylaxis.

Wearable Patch Appears Beneficial for Kids with Peanut Allergy

By October 26, 2016

Initial trial results have shown that a wearable patch, which delivers small amounts of peanut protein, can protect children and young adults with peanut allergies from the effects of accidental ingestion or exposure.

Epinephrine Auto-Injector AUVI-Q to Be Relaunched

By October 26, 2016

Kaléo announced today that they will reintroduce AUVI-Q (epinephrine injection, USP) to the U.S. market in the first half of 2017.

CDC: Confirm Penicillin Allergy in Patients Who Report One

By September 27, 2016

About 80% of patients with a penicillin allergy lose their sensitivity by 10 years following their reaction.

Impax: Generic Epinephrine Auto-Injector Available

By August 30, 2016

Impax Labs issued an update on its Epinephrine Injection, USP Auto-Injector 0.15mg and 0.3mg, the generic of Adrenaclick, indicating the product is currently available.

Mylan to Launch Generic EpiPen Auto-Injector

By August 29, 2016

Mylan announced it will launch Epinephrine Injection, the first generic version of EpiPen Auto-Injector at a list price of $300 per 2-pack carton.

Mylan Announces Steps to Expand EpiPen Access

By August 25, 2016

Mylan announced it is taking steps to expand patient access to EpiPen (epinephrine injection) and EpiPen Jr. Auto-Injectors by enhancing existing programs to assist patients who face higher costs.

Evaluating Anaphylaxis Risk in Siblings of Peanut Allergic Children

June 14, 2016

Parents are anxious about introducing peanuts at home without prior skin testing

FDA Rejects Anaphylaxis Drug Again, Requires More Data

By June 06, 2016

Adamis Pharmaceuticals announced that the Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) to the New Drug Application (NDA) for Epinephrine Injection USP 1:1000 0.3mg Pre-filled Single Dose Syringe (PFS) for the emergency treatment of acute anaphylaxis.

Treatment Options for Managing ACEI-Induced Angioedema

By June 03, 2016

For the management of angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema, use of fresh frozen plasma and complement 1 esterase (C1) inhibitor appear to be safe and effective whereas ecallantide should be avoided, a study published in the American Journal of Health-System Pharmacy concluded.

Labeling for Anaphylaxis Txs Updated to Include Injury, Infection Information

By May 25, 2016

The labeling for several epinephrine injection products has been updated to include information regarding injection-related injury and serious infections at the injection site.