Aminocaproic Acid Injection Rx

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Aminocaproic Acid Injection

Bleeding disorders
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Generic Name and Formulations:

Aminocaproic acid 250mg/mL; soln for IV infusion after dilution; contains benzyl alcohol.

Select therapeutic use:

Indications for Aminocaproic Acid Injection:

Bleeding associated with fibrinolysis.

Adult:

4–5g (in 250mL of diluent) by IV infusion during the 1st hour, then 1g/hour (in 50mL of diluent) for 8 hours or until bleeding is controlled.

Children:

Not recommended.

Contraindications:

Active intravascular clotting process. Disseminated intravascular coagulation without concomitant heparin.

Warnings/Precautions:

Upper urinary tract bleeding: not recommended. Cardiac, hepatic or renal disease. Risk of myopathy with long-term use; monitor creatine phosphokinase (CPK); discontinue if CPK rises. Avoid rapid IV administration. Neonates. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Avoid concomitant Factor IX complex or Anti-inhibitor Coagulant concentrates; may increase thrombosis risk.

See Also:

AMICAR TABLETS

AMICAR ORAL SOLUTION

Pharmacological Class:

Hemostatic.

Adverse Reactions:

Inj site reactions, bradycardia, hypotension, GI upset, edema, headache, malaise, CNS effects, thrombosis, others; rare: myopathy.

How Supplied:

Tabs—100; Oral soln—473mL; Inj—contact supplier