Allergic Disorders

Co-Occurrence of Autoimmunities for Diabetes, Celiac Disease Examined

October 11, 2017

The researchers found that IAs alone, tTGAs alone, and both appeared in 367, 808, and 90 children, respectively, with co-occurrence significantly exceeding the expected rate.

Early-Life Antibiotic Use and Celiac Disease: Is There an Association?

October 10, 2017

The researchers found that exposure to and frequency of use of any antibiotic assessed in the study in early life or before seroconversion was not associated with the risk of developing islet or celiac disease autoimmunity.

Asthma Drug Linked to Neuropsychiatric Adverse Events

By September 21, 2017

Results found that overall depression was the most commonly reported adverse event in the VigiBase group while headaches were the most frequent adverse event reported for the Dutch database.

Xolair Re-Treatment Still Effective in Chronic Spontaneous Urticaria

By September 19, 2017

Among the re-treated patients, almost 90% achieved symptom control (UAS7 ≤6) within 3 months. During both dosing periods, Xolair 150mg and 300mg were well-tolerated

AAP: School Workers Should Be Trained in Epinephrine Admin

September 19, 2017

Fifteen percent of participants reported that at least 1 dose of epinephrine was administered in their school by anyone, themselves included, in 2015 to 2016, compared with 24% in 2014 to 2015.

Possible Diagnostic, Therapeutic Target ID'd for Child Milk Allergies

September 13, 2017

The researchers found that among the micro RNAs (miRNAs) differently expressed, 2 were up-regulated and 14 were down-regulated in children with active CMA versus healthy controls.

Researchers Develop Portable Food Allergen-Detection System

By September 07, 2017

Most products were accurate to their stated label, however most products did contain at least 1 unspecified antigen, for instance, "brand of nut-free cookies contained gluten, whereas a gluten-free brand contained a peanut allergen," the authors write.

Penicillin Safety in Those with Allergy History But Negative Skin Test

By August 24, 2017

The authors reported that zero patients developed an immediate hypersensitivity reaction during these courses of administration.

Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study

By August 17, 2017

Results found that 4 children initially treated with PPOIT and 6 treated with placebo had allergic reactions to peanut intake, none experience prophylaxis.

Celiac Disease Linked to Increased Risk of Pneumococcal Infection

By August 15, 2017

After adjusting for socioeconomic index, diabetes, level of education, sex and age, an increased risk of pneumococcal infection among celiac disease patients was noted.

FDA: Severe Hypersensitivity, Death Following Curcumin Injection

By August 04, 2017

In March and May 2017, two patients given intravenous (IV) infusions of curcumin emulsion compounded with polyethylene glycol (PEG) 40 castor oil reported having immediate hypersensitivity reactions.

House Dust Mites May Induce lgE Sensitization to Antigens for Some

July 28, 2017

Researchers used IgE immunoblotting to analyze plasma samples from 179 atopic dermatitis patients for IgE-reactivity to a panel of micro-arrayed house dust mites allergen molecules.

Epinephrine Auto-Injector for Infants, Small Children Gets Priority Review

By July 27, 2017

The company has indicated that if the new auto-injector is approved they expect it to be available for patients in the first half of 2018.

Oral Allergy Treatments: OTC

July 25, 2017

A comparative dosing chart of over-the-counter (OTC) medications for allergy treatment.

Lannett Approved for Generic Periactin

By July 24, 2017

is used to treat various allergic reactions such as perennial and season allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhaled allergens or foods.

Delayed Anaphylaxis Treatment Often Occurs in Children

July 13, 2017

The researchers found that 36.3% of the children received epinephrine before arrival at the emergency department or UCC.

Vitamin D Supplementation Assessed for Preventing Allergic Diseases

July 12, 2017

The researchers found that based on very low certainty in the body of evidence across examined studies, vitamin D supplementation may not reduce the risk of developing allergic diseases.

Recommendations Issued in Response to Hymenoptera Venom Extract Shortage

July 10, 2017

Facing expected season-long shortage, doctors asked to urge patients to carry epinephrine auto-injectors

How Accurate Are Parent-Reported Penicillin Allergies?

July 05, 2017

Of 302 children with low-risk symptoms, 100 were tested for penicillin allergy using a standard, three-part testing process.

Symjepi Approved for Emergency Anaphylaxis Treatment

By June 16, 2017

Symjepi should only be injected into the anterolateral aspect of the thigh; injection into other areas such as the buttocks or the hands and feet may result in adverse effects and may also not provide effective treatment of anaphylaxis.

Recall Issued for Allergy Nasal Spray

By June 14, 2017

While testing did not reveal the presence of the microorganism, the recall is being conducted out of an abundance of caution, as use of contaminated product can be especially concerning for immunocompromised patients.

Time Course for Omalizumab Examined in Early, Late Allergic Reaction

June 09, 2017

The researchers observed a significant reduction in EAR after 4 weeks (change in forced expiratory volume in 1 second [ΔFEV1], 28 versus 11%; P<0.001; exhaled nitric oxide, 86 versus 53 ppb; P<0.05).

FDA Approves Zerviate for Allergic Conjunctivitis

By June 01, 2017

Zerviate is the first topical ocular formulation of cetirizine.

Approximately 4% of Americans Have a Food Allergy

June 01, 2017

Researchers find most common food allergen groups are shellfish, fruit or vegetable, dairy, and peanut

Quality of Life May Drop for Some During Oral Immunotherapy

May 30, 2017

Patients with better QOL at baseline, might deteriorate after therapy

Delayed Allergic Reaction Triggered by Meat Linked to Tick Bites

By May 24, 2017

States in the Midwest and South appear to have the highest prevalence of both alpha-gal allergy and rickettsial diseases transmitted by the Lone Star tick or Amblyomma americanum.

New Supplement Available for Relief of Allergy Symptoms

By May 24, 2017

In aclinical trial, AllerVarx decreased total symptom scores by ~70% and decreased the use of anti-allergic meds by ~73%.

Case: Exercise-Induced Anaphylaxis After Shrimp Consumption

May 17, 2017

FDEIA due to shrimp consumption reported in 18-year-old with specific IgE antibodies against 43 kDa

Are Expired EpiPens Still Effective?

May 10, 2017

Patients at a community clinic in San Diego were asked to bring in unused, expired EpiPens so they could be examined.

Wearable Devices Growing but Data Collection Remains a Challenge

April 24, 2017

Data from wearables do not always flow into electronic health record (EHR) systems, or do not appear in a format that physicians can use.