Allergic Disorders

Xolair Designated Breakthrough Therapy for Food Allergies

By August 13, 2018

The FDA designation was supported by data from 7 studies evaluating the safety and efficacy of Xolair against various food allergens (eg, peanut, milk, egg, others).

Anaphylaxis Management

August 03, 2018

Anaphylaxis management for outpatients, inpatients, and patients at discharge.

Child-Targeted Gluten-Free Products No Healthier

July 23, 2018

Compared with child-targeted products without a GF claim, child-targeted GF products had lower levels of sodium, total fat, and saturated fat, and also had less protein, and a higher percentage of calories from sugar.

Aspirin Desensitization May Improve Alcohol-Induced Symptoms in AERD Patients

By July 11, 2018

In addition to respiratory sensitivity to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), patients with AERD oftentimes experience an additional allergic reaction when drinking alcohol.

Tick-Caused Meat Allergy on the Rise in the United States

July 09, 2018

Hives, skin rash, stomach problems, headaches, and trouble breathing are among the symptoms of the meat allergy. There is no treatment or cure.

Penicillin Allergy Linked to MRSA, <i>C. Difficile</i> Risk

June 29, 2018

Also among patients with penicillin allergy, the adjusted incidence rate ratios for antibiotic use were 4.15, 3.89, and 2.1 for macrolides, clindamycin, and fluoroquinolones, respectively. Increased use of β-lactam alternative antibiotics accounted for 55 and 35% of the increased risk of MRSA and C. difficile, respectively.

Allergic Conjunctivitis Treatments

June 26, 2018

A comparative dosing chart of prescription and over-the-counter (OTC) medications for allergic conjunctivitis treatment.

Most Adults Don't Use Their Epinephrine Auto-Injectors During Reactions

By June 21, 2018

Most adults (52%) reported that an EAI was not used during their most severe reaction, even though it would have been beneficial, 45% said they didn't have it with them at the time.

Pediatric Chronic Rhinosinusitis: Treatment Options to Consider

By June 20, 2018

Because determining an appropriate treatment plan for a patient depends on the subtype of the disease, it is imperative for providers to know and understand the underlying mechanisms of CRS as well as the components included in a medical evaluation of a patient.

Intranasal Epinephrine for Anaphylaxis Looks Promising in Early Study

By June 14, 2018

The pharmacokinetics trial, which included 60 participants with seasonal allergies, also demonstrated rapid drug absorption with the intranasal spray.

Adenoid, Tonsil Removal May Affect Later Respiratory Risks

June 08, 2018

Participants were evaluated in linked national registers up to 2009, and incidence of disease was examined up to age 30 years, with adjustment for 18 covariates.

Some Common Allergies Linked to Odds of Autism in Children

June 08, 2018

Significant, positive link for common allergies, especially food allergy, with autism

Recall: Rhinitis Treatment May Contain Small Glass Particles

By May 31, 2018

Fluticasone Propionate Nasal Spray is a corticosteroid indicated for the management of the nasal symptoms of perennial nonallergic rhinitis in adults and pediatric patients aged 4 years and older.

Parents Have Concerns Over Food Allergy Precautions at Schools

May 30, 2018

The majority of parents felt that the polices at their child's school were helpful, but most also believed that implementation of additional polices was necessary, including availability of stock epinephrine (94.2%).

Is Cetirizine Use During Pregnancy Linked to Adverse Outcomes?

By May 21, 2018

To assess pregnancy outcomes associated with CTZ use, a retrospective analysis was conducted using the UCB Pharma Patient Safety Database to search for pregnancies up to February 28th, 2015.

Impact of Allergic Rhinitis, Rhinoconjunctivitis on Adolescents "Far-Reaching"

By May 21, 2018

A total of 27 articles were identified. Of these, 6 evaluated symptoms, 9 assessed QOL, 5 studied daily activities, 3 evaluated emotional aspects, 6 assessed sleep, 7 studied education, and 2 evaluated treatment burden.

Concerns Over EpiPen Supply Prompt Statement from Mylan

By May 09, 2018

Intermittent supply constraints due to manufacturing delays from Mylan's manufacturing partner, Meridian Medical Technologies, have resulted in varying supply levels.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

By May 08, 2018

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Auvi-Q 0.1mg Auto-Injector Available Soon for Infants, Toddlers

By April 26, 2018

The supplemental New Drug Application (sNDA) for the 0.1mg strength was granted Priority Review by the Food and Drug Administration (FDA).

Birch Pollen-Related Foods Can Trigger Dermatitis Reactions

April 23, 2018

Of those with allergic reactions, 32 patients exhibited significant deterioration of AD. Compared to nonresponders, responders showed significantly higher specific immunoglobulin E (IgE) levels to birch pollen and apple in addition to a higher prevalence of allergic rhinoconjunctivitis.

Pathway modification reduces admissions for pediatric anaphylaxis

April 11, 2018

Inpatient and observation unit admissions for pediatric anaphylaxis decreased by more than half following implementation of a revised clinical care pathway.

Most Parents Willing to Enroll Child in Food Allergen Trials

April 04, 2018

The researchers found that about half of the caregivers reported that they would be willing to enroll their child in a clinical trial (53.3%); 38.3% may be willing to enroll their child, while 8.3% would not enroll their child.

Most Patients Select Suboptimal Medications for Allergic Rhinitis

April 03, 2018

The researchers found that just under two-thirds of customers (63.2%) had a doctor's diagnosis for the symptoms for which they were selecting treatment. The majority of participants (70%) self-selected their medications.

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

April 03, 2018

The researchers found that 7.6% of included children were prescribed a histamine-2 receptor antagonist (H2RA), 1.7 percent a proton pump inhibitor (PPI), and 16.6% an antibiotic during the first 6 months of life.

Sinuva Sinus Implant Launched to Treat Recurrent Nasal Polyps

By April 02, 2018

Sinuva can be implanted during a routine physician visit under local or topical anesthesia.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

By March 26, 2018

Allergen avoidance, drug therapy, and allergen immunotherapy are all treatment options for allergic asthma.

Death After Bee Venom Apitherapy in Previously Tolerant Patient

By March 21, 2018

In this case, a 55-year-old woman developed wheezing, dyspnea, and sudden loss of consciousness during her apitherapy session in which she received live bee stings to improve muscular contractures and stress.

Alternative Grass Peptide Tx Shows Promise in Reducing Allergy Symptoms

March 16, 2018

Compared to the placebo group, the LPP group had reduced reactivity to a conjunctival provocation test (P<0.001) and, during the pollen season, a lower rhinoconjunctivitis quality of life global score (P=0.005).

Symjepi vs EpiPen: Incorrect Usage Rates Among Untrained Teens

By March 08, 2018

The study enrolled 34 adolescents aged 12 to 17 years old who had no familiarity with an epinephrine device (naive) and did not receive training during the study.

Peanut Allergy Oral Immunotherapy Effective in Phase 3 Study

By February 21, 2018

With regard to adverse events, 12.4% of AR101-treated patients discontinued treatment due to treatment-related side effects; these included gastrointestinal adverse events (6.7%) and systemic allergic hypersensitivity reactions (2.7%).