Sinuva Sinus Implant Launched to Treat Recurrent Nasal Polyps

Sinuva can be implanted during a routine physician visit under local or topical anesthesia.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

Allergen avoidance, drug therapy, and allergen immunotherapy are all treatment options for allergic asthma.

Death After Bee Venom Apitherapy in Previously Tolerant Patient

In this case, a 55-year-old woman developed wheezing, dyspnea, and sudden loss of consciousness during her apitherapy session in which she received live bee stings to improve muscular contractures and stress.

Symjepi vs EpiPen: Incorrect Usage Rates Among Untrained Teens

The study enrolled 34 adolescents aged 12 to 17 years old who had no familiarity with an epinephrine device (naive) and did not receive training during the study.

Peanut Allergy Oral Immunotherapy Effective in Phase 3 Study

With regard to adverse events, 12.4% of AR101-treated patients discontinued treatment due to treatment-related side effects; these included gastrointestinal adverse events (6.7%) and systemic allergic hypersensitivity reactions (2.7%).

Survey: Most At-Risk Patients Don't Carry Two Epinephrine Auto-Injectors

Most respondents did not carry 2 EAIs in order to keep 1 EAI in another location.

Varubi Labeling Updated to Warn of Serious Hypersensitivity Reactions

Anaphylaxis, anaphylactic shock and other serious hypersensitivity reactions have been reported.

Odactra Available for House Dust Mite-Induced Allergic Rhinitis

Odactra is an allergen extract indicated as immunotherapy for house dust mite (HDM)-induced allergic rhinitis.

New Flu Vaccine Guidelines Issued for Patients With Egg Allergy

The updated parameter stresses that no special precautions are needed or recommended for those with egg allergy.

Auvi-Q 0.1mg Auto-Injector Approved for Infants, Small Children

Auvi-Q 0.1mg is the first epinephrine auto-injector specifically designed for the treatment of life-threatening allergic reactions, including anaphylaxis, in infants and small children weighing 16.5 to 33 pounds.

FlutiCare Nasal Spray Now Available OTC to Relieve Allergy Symptoms

FlutiCare will be available OTC with the same prescription strength and same delivery method as Flonase and ClariSpray.

Seasonal Allergic Rhinitis Treatment Guidelines Updated

The guidelines focus on three key clinical statements.

HydraSense Nasal Care Line Available for Infants and Children

hydraSense hydrates and soothes dry and uncomfortable nasal passages.

Are Pediatricians Addressing the Topic of Early Peanut Introduction With Parents?

Of those who completed the survey, 38% scored a 1 or lower on whether they complied with guidelines.

Asthma Drug Linked to Neuropsychiatric Adverse Events

Results found that overall depression was the most commonly reported adverse event in the VigiBase group while headaches were the most frequent adverse event reported for the Dutch database.

Xolair Re-Treatment Still Effective in Chronic Spontaneous Urticaria

Among the re-treated patients, almost 90% achieved symptom control (UAS7 ≤6) within 3 months. During both dosing periods, Xolair 150mg and 300mg were well-tolerated

Researchers Develop Portable Food Allergen-Detection System

Most products were accurate to their stated label, however most products did contain at least 1 unspecified antigen, for instance, "brand of nut-free cookies contained gluten, whereas a gluten-free brand contained a peanut allergen," the authors write.

Penicillin Safety in Those with Allergy History But Negative Skin Test

The authors reported that zero patients developed an immediate hypersensitivity reaction during these courses of administration.

Peanut Allergy Tx Efficacy Examined in 4-Year Follow-Up Study

Results found that 4 children initially treated with PPOIT and 6 treated with placebo had allergic reactions to peanut intake, none experience prophylaxis.

Celiac Disease Linked to Increased Risk of Pneumococcal Infection

After adjusting for socioeconomic index, diabetes, level of education, sex and age, an increased risk of pneumococcal infection among celiac disease patients was noted.

FDA: Severe Hypersensitivity, Death Following Curcumin Injection

In March and May 2017, two patients given intravenous (IV) infusions of curcumin emulsion compounded with polyethylene glycol (PEG) 40 castor oil reported having immediate hypersensitivity reactions.

Epinephrine Auto-Injector for Infants, Small Children Gets Priority Review

The company has indicated that if the new auto-injector is approved they expect it to be available for patients in the first half of 2018.

Symjepi Approved for Emergency Anaphylaxis Treatment

Symjepi should only be injected into the anterolateral aspect of the thigh; injection into other areas such as the buttocks or the hands and feet may result in adverse effects and may also not provide effective treatment of anaphylaxis.

Recall Issued for Allergy Nasal Spray

While testing did not reveal the presence of the microorganism, the recall is being conducted out of an abundance of caution, as use of contaminated product can be especially concerning for immunocompromised patients.

FDA Approves Zerviate for Allergic Conjunctivitis

Zerviate is the first topical ocular formulation of cetirizine.

Delayed Allergic Reaction Triggered by Meat Linked to Tick Bites

States in the Midwest and South appear to have the highest prevalence of both alpha-gal allergy and rickettsial diseases transmitted by the Lone Star tick or Amblyomma americanum.

New Supplement Available for Relief of Allergy Symptoms

In aclinical trial, AllerVarx decreased total symptom scores by ~70% and decreased the use of anti-allergic meds by ~73%.

Are Expired EpiPens Still Effective?

Patients at a community clinic in San Diego were asked to bring in unused, expired EpiPens so they could be examined.

Serious Adverse Events Linked to Short-Term Corticosteroid Use

The data revealed the most common indications for short-term corticosteroid use to be upper respiratory tract infections, spinal conditions, and allergies.

Potential Defect Prompts EpiPen Recall

The recall affects both the EpiPen Auto-Injector 0.15mg and 0.3mg strengths and the product was distributed by Mylan Specialty between December 2015 and July 2016.

Xyzal Allergy 24HR Now Available OTC

Xyzal Allergy 24HR is recommended for use in patients aged ≥6 years, with Children's Xyzal Allergy 24HR oral solution is recommended for use in patients aged ≥2 years.

Novel Allergic Rhinitis Nasal Spray Shows Promise in Phase 3 Trial

Results showed that GSP 301 was tied to statistically significant improvements from baseline for the primary endpoint when compared to placebo (P<0.001), olopatadine (P=0.028), and mometasone (P=0.019).

Skin Prick and slgE Test Compared for Agreement in Allergic Disease

SPT and sIgE displayed moderate agreement in their correlation with allergic disease in a cohort of 10-year olds, and showed no significant difference for the area under the curve for allergic diseases.

Probiotic Combo Shows Promise in Seasonal Allergies

A triple combination probiotic was found to improve the rhinoconjunctivitis-specific quality of life for individuals with seasonal allergies when compared with placebo.

Odactra Approved for House Dust Mite Allergies

Odactra provides patients an alternative treatment to allergy shots.

Two Asthma Meds Show Promise in Halting Lethal Pneumonia

A mice model demonstrated that treating severe influenza with Singulair or Accolate may prevent severe pneumonia.

Steroid-Releasing Implant Improves Surgical Outcomes in Chronic Sinusitis

Propel Contour features an hourglass design and is specifically designed to conform to the sinus ostia.

AAP: Epinephrine Auto-Injector, Action Plan Crucial for Anaphylaxis Management

This clinical report from the American Academy of Pediatrics is an update on their 2007 clinical report.

Flonase Sensimist Available OTC for Allergy Relief

GSK Consumer Healthcare announced the availability of Flonase Sensimist Allergy Relief (fluticasone furoate), an over-the-counter (OTC) treatment for symptoms associated with seasonal and perennial allergies for patients aged ≥12 years.

Children with Transverse Myelitis Should Be Screened for Celiac Disease

Transverse myelitis (TM) can be a manifestation of celiac disease (CD) in young children, according to a case report published online February 2 in Pediatrics.

FDA: Life-Threatening Allergic Reactions Linked to Skin Antiseptic

Reactions can occur within minutes of exposure.

Prescription Allergy Drug Soon to Be Available OTC

Both tablets and oral solution will be available over-the-counter.

Risk Factors Associated with NSAID Hypersensitivity Reaction ID'd

Data from a retrospective cohort study found that about 1 in 5 non-steroidal anti-inflammatory drug (NSAID) adverse drug reactions is a hypersensitivity reaction.

Voice-Guided Epinephrine Auto-Injector Soon to Be Available

Kaléo announced that Auvi-Q (epinephrine injection) Auto-injector will be available in pharmacies beginning February 14th.

Update to Recommended Times for Infant Food Introduction

In a position paper published in the January issue of the Journal of Pediatric Gastroenterology and Nutrition, guidance is presented in relation to complementary foods and their introduction into an infant's diet.

Clinical Guidelines Issued for Preventing Peanut Allergy

"We expect that widespread implementation of these guidelines will prevent the development of peanut allergy in many susceptible children and ultimately reduce the prevalence of peanut allergy in the United States," said NIAID Director Anthony S. Fauci, MD.

Novel DNA Vaccine for Peanut Allergy Gets Fast Tracked

Astellas and Immunomic announced that the Food and Drug Administration (FDA) has granted Fast Track designation to its candidate ASP0892 for the mitigation of severe hypersensitivity reactions due to peanut allergy.

Authorized Generic for EpiPen Coming Next Week

Mylan announced the launch of Epinephrine Injection Auto-Injector, the authorized generic for EpiPen Auto-Injector.

Study on Anaphylaxis Incidence Shows Low Epinephrine Auto-Injector Prescribing Rates

Findings from a study published in the Annals of Allergy, Asthma & Immunology suggest the ongoing difficulty in diagnosing anaphylaxis as evident by the low prescribing rates of epinephrine auto-injector in cases of anaphylaxis.

Wearable Patch Appears Beneficial for Kids with Peanut Allergy

Initial trial results have shown that a wearable patch, which delivers small amounts of peanut protein, can protect children and young adults with peanut allergies from the effects of accidental ingestion or exposure.

Epinephrine Auto-Injector AUVI-Q to Be Relaunched

Kaléo announced today that they will reintroduce AUVI-Q (epinephrine injection, USP) to the U.S. market in the first half of 2017.

CDC: Confirm Penicillin Allergy in Patients Who Report One

About 80% of patients with a penicillin allergy lose their sensitivity by 10 years following their reaction.

Study Finds Link Between Early Antibiotic Exposure and Later Life Allergies

Taking antibiotics at a very young age could increase the risk of certain allergic conditions later in life, according to research presented at the annual European Respiratory Society International Congress, held from in London.

Mylan Announces Steps to Expand EpiPen Access

Mylan announced it is taking steps to expand patient access to EpiPen (epinephrine injection) and EpiPen Jr. Auto-Injectors by enhancing existing programs to assist patients who face higher costs.

Anti-Nausea Drug Evaluated in Acute Food Protein-Induced Enterocolitis Syndrome

A retrospective study found that the nausea and vomiting preventative treatment, ondansetron, was more effective than traditional therapy in inducing remission of vomiting in patients with acute food protein induced enterocolitis syndrome (FPIES).

Peanut Oral Immunotherapy Effective in Allergic Preschool Children

A study reported that close to 80% of peanut-allergic preschool children successfully integrated peanut-containing foods into their diets after treatment with peanut oral immunotherapy (OIT).

Allergic Rhinitis Patients May Benefit From House Dust Mite Immunotherapy

For patients with allergic rhinitis (AR), house dust mite (HDM) sublingual immunotherapy is effective and seems safe, according to a study published online July 29 in Allergy.

FDA Approves New Rx-to-OTC Switch for Allergy Nasal Spray

The OTC treatment is for symptoms associated with seasonal and perennial allergies in patients aged ≥2 years.

FDA Rejects Anaphylaxis Drug Again, Requires More Data

Adamis Pharmaceuticals announced that the Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) to the New Drug Application (NDA) for Epinephrine Injection USP 1:1000 0.3mg Pre-filled Single Dose Syringe (PFS) for the emergency treatment of acute anaphylaxis.

Treatment Options for Managing ACEI-Induced Angioedema

For the management of angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema, use of fresh frozen plasma and complement 1 esterase (C1) inhibitor appear to be safe and effective whereas ecallantide should be avoided, a study published in the American Journal of Health-System Pharmacy concluded.

Labeling for Anaphylaxis Txs Updated to Include Injury, Infection Information

The labeling for several epinephrine injection products has been updated to include information regarding injection-related injury and serious infections at the injection site.

Xylitol-Based Nasal Care Products Available OTC

Xlear have announced that their line of xylitol-based products for adults with upper respiratory problems will be available at 1,300 Target stores nationwide.

Consider Alternatives to Anticholinergic Meds in Older Patients, Say Researchers

Older patients taking anticholinergic (AC) medication scored significantly lower on three separate brain atrophy and dysfunction tests compared to matched controls who took no AC medication.

FDA: Stop Using Recalled Portable Emergency Oxygen Device

The Food and Drug Administration (FDA) issued a safety communication recommending against the use of OxySure Portable Emergency Oxygen System, Model 615.

Mislabeled Dietary Supplements Prompt Recall

NOW Health Group announced a voluntary recall of 6 dietary supplements that were mislabeled due to a printing error by the label supplier.

Will the Proposed FDA Glove Ban Have an Impact on Practice?

The FDA has proposed a ban on most powdered gloves in the United States.

Update on Peanut Allergy Immunotherapy: A Test for Success?

Early changes in immune T-cell populations may aid researchers in determining which patients with peanut allergies will respond well to oral immunotherapy. They can also pinpoint which immune mechanisms are involved in the response, according to a study conducted by Stanford University researchers.

Many Parents Uninformed About Epinephrine Use for Kids' Food Allergies

Less than 40% of parents recall their pediatricians explaining when they are to use epinephrine in the event of their child having an allergic reaction.

Does Timing of DTaP Vaccine Impact Child's Allergy Risk?

Delaying immunization with diphtheria-tetanus-acellular pertussis (DTaP) vaccine was not associated with reduced risk of food allergy but children with delayed DTaP were found to have less eczema and used less eczema drugs, according to a study published in Allergy.

Some Childhood Allergies May Increase Risk of Heart Disease

Children with certain allergies are at double the risk of developing high blood pressure and cholesterol, a study conducted by researchers at Northwestern Medicine reported.

Emergency Med Recalled Due to Potential Inaccurate Dosage Delivery

Sanofi announced the voluntary recall of all Auvi-Q (epinephrine injection) due to a potentially inaccurate dosage delivery.

Nasal Allergy Spray Currently Unavailable

Merck has issued a letter to healthcare professionals letting them know that Nasonex (mometasone furoate monohydrate) Nasal Spray 50mcg is currently out of stock due to a manufacturing issue.

Why Probiotics Could Be Novel Tx for Food Allergies

Infants who developed intolerance to cow's milk showed significant differences in gut bacteria after being treated with probiotics, a new study conducted by researchers from the University of Chicago has found.

New Guidance for Clinicians on Peanut Introduction, Allergy Risk in Infants

The American Academy of Pediatrics (AAP) has issued interim guidance, in conjunction with 10 other medical organizations, supporting early rather than delayed peanut introduction during the period of complementary food introduction in infants.

Use Epinephrine for All Severe Allergic Reactions, Urge Experts

In a new article published in the Annals of of Allergy, Asthma and Immunology, experts recommend the use of epinephrine for all severe allergic reactions, even for patients at risk of an anaphylactic reaction.

Naramin in Single-Dose "Whistles" Launched

National Pharma announced the launch of Naramin (diphenhydramine), an oral solution in prefilled single-dose whistles.

Peanut Allergy Patch Gets Closer to FDA Submission

DBV Technologies announced that based its meeting with the Food and Drug Administration (FDA), it plans to initiate a global Phase 3 study of its investigational Viaskin Peanut epicutaneous immunotherapy (EPIT) patch for the treatment of peanut allergies.

Peanut Allergy Drug Designated Breakthrough Therapy

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to AR101, an oral immunotherapy for children and adolescents 4 to 17 years of age who are allergic to peanuts.

Investigational Peanut Allergy Tx Improves Tolerance in Younger Patients

Aimmune Therapeutics announced that the Phase 2 study of a novel investigational oral immunotherapy (AR101) for the treatment of peanut allergy met its primary endpoint of tolerating a cumulative amount of peanut protein of at least 443mg.

Scope, Impact of Asthma Epidemic Highlighted for Allergy and Asthma Awareness Month

The American College of Allergy, Asthma, and Immunology has developed an infographic titled "Scope and Impact of the Asthma Epidemic" that addresses vital statistics for asthma sufferers as well as the benefits of consulting an allergist for their care.

Could an OTC Allergy Med Help Treat HCV Infection?

An over-the-counter (OTC) medication indicated to treat allergy symptoms could potentially be used to treat hepatitis C virus (HCV) infection after a new study showed that it limited HCV virus activity in infected mice. The research was funded by the National Institutes of Health (NIH).

New Blood Test May Be Safer Way to Detect Food Allergies

A new blood test may be able to predict who will have severe allergic reactions to foods, researchers from Mount Sinai have reported.

Feraheme Label Updated with New Warnings, Contraindication

The Food and Drug Administration (FDA) has strengthened an existing warning regarding serious and potentially fatal allergic reactions that can occur with Feraheme (ferumoxytol; AMAG Pharmaceuticals).

Why a Clean House May Not Lower Asthma, Allergy Risk

Despite the widely accepted assumption that the rise in allergic disorders may be due to improved hygiene, a new study has found no connection between development of allergies and asthma and personal hygiene or home cleanliness.

Study: Mothers Report More GI Symptoms in Children With Autism

A new study has found that maternally reported gastrointestinal (GI) symptoms in children are more common in children with autism spectrum disorder (ASD) in the first three years of life compared to children with typical development or developmental delay (DD).

No More Latex-Free Claims, Recommends FDA

The Food and Drug Administration (FDA) is recommending that manufacturers stop using the labels "latex-free" or "does not contain latex" due to the scientific inaccuracy of these claims.

Can You Be Allergic to Cannabis?

Allergic disease associated with Cannabis sativa and use has been reported with increasing frequency, although it is still relatively uncommon. A new article published in the Annals of Allergy, Asthma and Immunology presents data on how Cannabis sativa can act as an allergen.

Infant Peanut Consumption Could Lower Risk of Allergy Development

Introducing peanut products into the diets of infants at high risk of developing peanut allergy was safe and led to an 81% reduction in the subsequent allergy development, reports a new study.

Dymista Granted Expanded Age Range

Meda announced that the Food and Drug Administration (FDA) has approved Dymista (azelastine HCl and fluticasone propionate) for the relief of symptoms of seasonal allergic rhinitis (SAR) in patients ages 6-11 who require treatment with both components.

Peanut Allergy Patch Shows Promise in Latest Study

Data from a Phase 2b trial showed that patients with peanut allergy using Viaskin Peanut (DBV Technologies) showed significant improvement using this epicutaneous immunotherapy (EPIT) after one year.

Can a Common Allergy Med Help Treat Lyme Disease?

Loratadine, an antihistamine found in over-the-counter allergy medicines, may be able to help kill the bacteria associated with Lyme disease (Borrelia burgdorferi).

Probiotic + Protein Combo Promising for Peanut Allergy in Children

A new oral therapy that combines a probiotic and peanut protein appears to be a successful immunotherapy for peanut allergy, based on a study conducted by researchers at Murdoch Childrens Research Institute at the Royal Children's Hospital in Australia.

FDA: Asthma Drug May Increase Risk of CV, Cerebrovascular Events

The Food and Drug Administration (FDA) is warning about a slightly increased risk of cardiovascular and cerebrovascular events among patients being treated with Xolair (omalizumab; Genentech and Novartis) for asthma compared to those not treated with Xolair.

QlearQuil Line Launched for Sinus and Allergy Symptoms

Vicks announced the launch of QlearQuil, a line of over-the-counter (OTC) products for the treatment of sinus and allergy symptoms.

Potential Allergen in Gluten-Free Foods, Warns FDA

The Food and Drug Administration (FDA) has issued an alert regarding an ingredient commonly found in gluten-free products that may cause anaphylaxis in patients with a legume allergy.

OTC Version of Flonase Approved by FDA

GlaxoSmithKline announced that the FDA has approved Flonase Allergy Relief (fluticasone propionate 50mcg spray) as a once-daily over-the-counter (OTC) treatment indicated for symptoms of seasonal and perennial allergic and nonallergic rhinitis in patients ≥4 years of age

Oralair SL Tab Launched for 5 Grass Allergens

Greer laboratories announced the launch of Oralair (Sweet Vernal, Orchard, Perennial Rye, Timothy and Kentucky Blue Grass Mixed Pollens Allergen Extract) sublingual allergy immunotherapy tablet.

Ranbaxy Recalls OTC Allergy Medication

Ranbaxy has announced a voluntary recall of 29,790 blister packs of an over-the-counter (OTC) allergy medication in the U.S. after an unacceptable number of blister defects were identified.

FDA Approves Short Ragweed Pollen Allergen SL Tab

The FDA announced the approval of Ragwitek (Ambrosia artemisiifolia; Merck), the first sublingual allergen extract to treat short ragweed pollen induced allergic rhinitis, with or without conjunctivitis.

FDA Approves Timothy Grass Pollen SL Tab

Merck announced that the FDA has approved Grastek (Timothy grass pollen allergen extract) Tablet for Sublingual Use as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis.