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AFEDITAB CR

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Generic Name for AFEDITAB CR

Nifedipine 30mg, 60mg; ext-rel tabs.

Legal Classification:

Rx

Pharmacological Class for AFEDITAB CR

Calcium channel blocker (dihydropyridine).

Manufacturer of AFEDITAB CR

Watson Pharmaceuticals, Inc.

Indications for AFEDITAB CR

Hypertension.

Adult dose for AFEDITAB CR

Swallow whole. Initially 30mg once daily, titrate over 7–14 days; usual maintenance dose: 30–60mg once daily; max 90mg/day.

Children's dosing for AFEDITAB CR

Not recommended.

Warnings/Precautions for AFEDITAB CR

Aortic stenosis. Angina. Severe obstructive coronary artery disease. Heart failure. Avoid abrupt cessation. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions for AFEDITAB CR

Hypotension, angina and heart failure possible with β-blockers (esp. timolol). Potentiated by quinidine (monitor heart rate; adjust dose); diltiazem, verapamil, doxazosin, ketoconazole, itraconazole, fluconazole, cimetidine, quinupristin/dalfopristin, erythromycin, nefazodone, valproic acid, (reduce nifedipine dose); amprenavir, atazanavir, delavirine, fosamprenavir, indinavir, nelfinavir, ritonavir, grapefruit juice (avoid). Antagonized by rifampin, rifapentine, phenytoin, phenobarbitone, carbamazepine, St. John's Wort. Potentiates digoxin, tacrolimus (monitor). Antagonizes doxazosin. Hypotension possible with fentanyl. Monitor oral anticoagulants. Hyperglycemia with acarbose.

Adverse Reactions for AFEDITAB CR

Headache, flushing/heat sensation, fatigue, dizziness, constipation, nausea, edema; rare: increased angina, acute MI.

How is AFEDITAB CR supplied?

Tabs—100, 500

Related Disease:

Hypertension

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