Addiction/dependence

Study Belies Common Notion That Opioid Patients Fail Outpatient Tapers

February 21, 2018

The researchers found that 38% of the 82 enrolled patients did not complete a 4-month follow-up survey and were considered to have dropped out. There was a negative correlation for depression and a positive correlation for baseline marijuana use with study completion.

Researchers Hope to Test Heroin Vaccine in Humans Soon

By February 14, 2018

Researchers investigated 20 different carrier protein/adjuvant combinations.

Addressing Sensitive Topics With Patients: An Interview With Windel Stracener, MD

By February 14, 2018

"Patients must feel that you are empathetic and do not judge them. This is key not only to discussing weight, but to any subject that comes up," said Dr Windel Stracener, a family practitioner for 22 years.

Spouse of Person With Alcohol Use Disorder at 'Rapid' Risk

February 08, 2018

After a first marriage to a spouse without AUD, the hazard ratios for AUD were 7.02 and 9.06, respectively, in women and men with a second marriage to a spouse with AUD.

FDA Analysis Shows Kratom Not "Just a Plant"

By February 07, 2018

Kratom should not be used to treat medical conditions, nor should it be used as an alternative to prescription opioids.

Premature Unusual Amnesia Syndrome Linked to Substance Use

January 30, 2018

"To our knowledge this report is the first to associate fentanyl with this amnestic syndrome," the authors write.

FDA: Increasing Number of Companies Selling Unapproved Opioid Cessation Txs

By January 24, 2018

These products have not been demonstrated to be safe or effective and may keep some patients from seeking appropriate, FDA-approved therapies.

DEA: Deregulation Allows NPs, PAs to Prescribe Opioid Use Disorder Treatment

By January 23, 2018

Nurse practitioners (NP) and physician assistants (PA) can now become DATA-Waived qualifying practitioners, allowing them to prescribe and dispense buprenorphine.

Impact of Marijuana Use on Cardiovascular Health Investigated

January 23, 2018

The researchers identified 13 studies examining associations between marijuana use and cardiovascular risk factors and 11 studies examining associations with clinical outcomes.

Is Pregabalin Effective for Benzodiazepine Discontinuation?

By January 11, 2018

For this study, researchers from the University of Michigan College of Pharmacy investigated the available evidence for the use of pregabalin in benzodiazepine discontinuation.

2009 to 2016 Shows Increase in Prenatal Marijuana Use

December 27, 2017

Greatest increases seen for pregnant females aged younger than 18 years, those aged 18 to 24 years

Urine Drug Monitoring Recommendations for Opioid Use in Chronic Pain

By December 15, 2017

For low-risk patient, testing should be conducted at least yearly, for those at moderate risk, ≥2 times a year, and for those at high risk, ≥3 times a year.

FDA Cracks Down on Companies Selling Street Drug Alternatives

By December 12, 2017

The warning letter explains how the claims made in the promotional materials for Legal Lean Syrup and Coco Loko demonstrate that the products are intended to be used as alternatives to illicit street drugs and that the products, as labeled and marketed, may pose safety concerns.

New Treatment Option for Opioid Use Disorder Gets Approval

By December 01, 2017

Sublocade should be used as part of a complete treatment program that includes counseling and psychosocial support.

FDA Grants Priority Review to Lofexidine for Opioid Withdrawal Management

By November 21, 2017

Lofexidine, an oral tablet, is a selective alpha 2-adrenergic receptor agonist that reduces the release of norepinephrine.

Nonmedical Rx Drug Use and Dating Violence: What's the Link?

November 20, 2017

Nonmedical use of prescription drugs linked to dating violence for male, female high school students

Clinical Characteristics of Endogenous Endophthalmitis Examined in Injection Drug Users

November 20, 2017

Injection drug users have fewer comorbidities and more improvement in visual acuity after intervention

Treatments Compared for Prevention of Opioid Relapse

November 20, 2017

Difficulty initiating XR-NTX accounts for difference in relapse rates in intent-to-treat population

Device to Help Reduce Symptoms of Opioid Withdrawal Gets FDA Approval

By November 16, 2017

The FDA approval is supported by a single-arm clinical study of 73 patients undergoing opioid physical withdrawal.

Methamphetamine Heart Failure May Present New Phenotype

November 15, 2017

"Clinicians are seeing more heart failure with meth use, suggesting heart failure due to methamphetamine use could be a new epidemic," said lead author, Marin Nishimura, MD, in a statement.

Concerns About Kratom Prompt Statement from FDA Commissioner

By November 14, 2017

Kratom is plant that grows naturally in Thailand, Malaysia, Indonesia and Papua New Guinea. It has gained popularity in the U.S., with some marketers touting it as a "safe" treatment with broad healing properties.

DEA: All Illicit Fentanyl Analogues Will Be Scheduled

By November 09, 2017

In the current situation prosecutors need to overcome 'evidentiary hurdles' in gaining convictions of traffickers for illicit fentanyls coming into the country through the mail, shipping systems or imported across the southwest border.

ASCO: Alcohol Initiative May Decrease Cancer Burden

November 08, 2017

The statement promotes public education related to the risks of alcohol abuse and certain types of cancer.

Cannabidiol Products Sold Online Often Have Inaccurate Labeling

November 08, 2017

The researchers found that the observed CBD concentration varied from 0.1 to 655.27 mg/mL (median, 9.45 mg/mL); the median labeled concentration was 15 mg/mL.

FDA Advisory Committees Reach Decision on Opioid Use Disorder Tx

By November 01, 2017

A Phase 3 study found that 300mg and 100mg doses of RBP-6000 had significantly greater abstinence rates when compared with placebo; 300mg/300mg: 41.3%; 300mg/100mg: 42.7%; placebo: 5.0%.

CDC Report Examines Tobacco Use By Industry, Occupation

October 30, 2017

The researchers found that 22.1% of working adults currently used any form of tobacco; 15.4, 5.8, 3, and 3.6% used cigarettes, other combustible tobacco, smokeless tobacco, and electronic cigarettes, respectively

Opioid Epidemic Declared Public Health Emergency

By October 27, 2017

Unlike a national emergency, which is what Mr. Trump has referred to the epidemic has, a public health emergency does not involved the release of any federal funds.

Alcohol May Contribute to Premature Mortality in Psoriasis Patients

By October 17, 2017

The researchers compared an cohort of patients with psoriasis (≥18 years of age) drawn from several databases to 20 patients without psoriasis who were matched by age, sex, and general practice (n=55,537 and 854,314 respectively).

Changing Marijuana Laws May Mean More Screening, Counseling Needed

October 10, 2017

In the changing legal environment, pediatric physicians must review their approach to screening for marijuana use and discussing the associated health consequences

Breath Sensor, App Combo Provide Novel Approach to Smoking Cessation

By October 06, 2017

The Carbon Monoxide Breath Sensor System (COBSS) informs the user how breath carbon monoxide levels are affected by their smoking behavior.