Acne

Altreno Now Available for Topical Treatment of Acne Vulgaris

By October 30, 2018

Altreno Lotion should be used with caution in patients with known sensitivity or allergy to fish.

Phase 3 Trials Examine Efficacy of Tretinoin Lotion for Tx of Acne

October 16, 2018

The researchers found that tretinoin 0.05% lotion demonstrated statistically significant superiority to vehicle in reducing inflammatory and non-inflammatory lesion counts (both P<.001) at week 12, as well as improving acne severity (P<.001).

Seysara Approved for the Treatment of Moderate to Severe Acne Vulgaris

By October 02, 2018

The approval was based on data from 2 large, multicenter, randomized, double-blind, placebo-controlled Phase 3 trials involving patients with moderate to severe facial acne vulgaris.

Altreno Approved for the Topical Treatment of Acne Vulgaris

By August 24, 2018

The approval was based on 2 double-blind clinical trials involving 1640 patients 9 years of age and older with moderate to severe acne vulgaris.

Treatment of Hidradenitis Suppurativa with SAPHO Syndrome: A Case Review

By June 21, 2018

The male patient presented in 2009 with a "3-year history of multiple interconnecting comedones in the axilla and inguinal regions, as well as scarring from previous lesions."

Combo Therapy Appears Safe, Effective for Severe Inflammatory Acne

By May 07, 2018

Treatment with the combination gel + oral doxycycline was associated with a 66.2% reduction in inflammatory lesions, a 58.7% reduction in non-inflammatory lesions, and a 62.6% reduction in total lesions at Week 12 vs baseline (P <.0001).

Acne Linked to Significantly Higher Risk of Major Depressive Disorder

February 09, 2018

The researchers found that the probability of developing MDD was 18.5 and 12% among patients with acne and in the general population without acne over the 15-year follow-up period.

FDA to Review Seysara for the Treatment of Moderate to Severe Acne

By December 26, 2017

Seysara (sarecycline) is a once-daily, oral, narrow spectrum tetracycline-derived antibiotic.

Long Term Antibiotic Use and Resistance Risk Assessed in Acne

December 18, 2017

The researchers found that resistant mutants with the 23S rRNA mutation were not isolated when P. acnes mutants were exposed to clarithromycin after being incubated in broth without antimicrobials.

Combo Tx Shows Promise for Improving Acne Scars

November 09, 2017

The researchers found that for the 52 patients completing the trial, there was a greater decrease in the mean ECCA score in the combination treatment group compared with the microneedling-only group.

Teva Launches Generic Epiduo Gel

By July 28, 2017

Biochemical and pharmacological profile studies have demonstrated that adapalene is a modulator of cellular differentiation, keratinization and inflammatory processes.

Cutaneous Procedures During Isotretinoin Rx May Be OK

June 29, 2017

The researchers found that for patients currently receiving or having recently completed isotretinoin therapy, there was insufficient evidence to support delaying manual dermabrasion, superficial chemical peels, cutaneous surgery, laser hair removal, and fractional ablative and nonablative laser procedures.

Acne Drug May Negatively Impact Tattoo Healing

June 22, 2017

The authors note that the tattooing was uneventful, but the patient presented with impaired tattoo healing. There was no infection, and with use of a proper moisturizer the tattoo eventually healed.

Vitamin B12 Therapy Linked to Acneform Eruptions

June 19, 2017

"A careful pharmacologic history is therefore necessary in all patients with acneiform eruptions," the authors write.

Minolira Approved for Moderate to Severe Acne Vulgaris

By May 10, 2017

In 1 of the 2 trials the approval was based on patients in the Minolira group had a 43.1% mean improvement in inflammatory lesions vs. 31.7% of patients in the placebo group.

Out-of-Pocket Spending for Topical Steroids Investigated

May 02, 2017

The researchers found that patients' out-of-pocket spending for topical steroids was $333.7 million. There was a 226.5% increase in total annual spending, from $237.6 million to $775.9 million.

Should Acne Tx Change Target to Improving Healthy Microbiota?

April 06, 2017

The researchers found that in the group without acne, the bacterial community was enriched with genes related to bacterial metabolism, thought to be key in preventing harmful bacteria from colonizing the skin.

Sarecycline Promising for Moderate to Severe Acne

By March 27, 2017

Allergan and Paratek announced positive results from two Phase 3 studies of sarecycline for the treatment of moderate to severe acne.

OXY On-The-Go Acne Stick Launched

By March 24, 2017

The new OXY On-The-Go Acne Stick allows teens to spot-treat at any time; it can be used for different skin types.

'On-the-Go' Treatment for Acne Available Soon

By March 03, 2017

Cutanea Life Sciences has announced the availability of Aktipak (erythromycin and benzoyl peroxide) Gel, 3%/5% for the topical treatment of acne vulgaris.

Economic Impact of Skin Disease Highlighted in New Report

March 03, 2017

In the United States, dermatological conditions cost 75 billion in 2013, researchers say

Acne Gel Recalled Due to Presence of Mold

By February 10, 2017

Perrigo announced a recall of 10 lots of Clindamycin Phosphate and Benzoyl Peroxide Gel (1.2%/5%) due to the presence of a small amount of mold on the caps of the tubes.

Mixed Results for Acne Gel Candidate in Phase 3 Trials

By January 27, 2017

Novan has announced results from its two Phase 3 trials of SB204 gel 4%, its investigational candidate for the treatment of acne vulgaris.

Top 10 Most Costly Conditions in the U.S. Announced in New Report

By December 27, 2016

The highest amounts of spending were seen with these 10 conditions.

Personal, Environmental Factors Involved in Adult Female Acne

November 17, 2016

Factors that are associated with the appearance of acne in adult women include family history, personal history of acne, having no previous pregnancies, having hirsutism, and having a high level of psychological stress

Can Topical Steroids Reduce Retinoid-Induced Irritation in Acne Patients?

November 02, 2016

Doesn't meet primary end points of improved acne severity, mitigation of retinoid-induced irritation

Oral Contraceptive Rajani Now Available

By October 14, 2016

Teva announced the availability of Rajani (drospirenone/ethinyl estradiol/levomefolate calcium tablets and levomefolate calcium tablets), the generic version of Bayer HealthCare's Beyaz.

Perrigo Granted Tentative Approval for Generic Epiduo Gel

By September 01, 2016

Perrigo announced it has received tentative approval from the Food and Drug Administration (FDA) for Adapalene and Benzoyl Peroxide Gel, the generic version of Galderma's Epiduo Gel.

FDA Approves First OTC Retinoid Acne Treatment

By July 08, 2016

The Food and Drug Administration (FDA) has approved Differin Gel (adapalene; Galderma) 0.1% for over-the-counter (OTC) treatment for acne in patients aged ≥12 years.

Acne Outcomes Vary Based on Hormonal Contraceptive Used

By June 22, 2016

A patient-reported study of hormonal contraceptives has found a significantly varied effect on acne among commonly prescribed agents.