Study patients were randomized to Pradaxa 150mg twice daily or warfarin (target INR 2-3) and remained on this treatment for the trial duration.
Results showed a similar change in baseline raw score of spatial working memory strategy index of executive function in the evolocumab and placebo groups (mean change from baseline -0.2 vs. -0.3, respectively).
During the past 2 decades, the use of antihypertensive drug use has "increased remarkably," noted Jens Sundboll, of Aarhus University Hospital, Aarhus, Denmark
When compared to bivalirudin, higher bleeding complications and all-cause mortality were seen with unfractionated heparin among patients undergoing PCI.
Although MI is known to be common among patients with CKD, not much is known about the incidence of post-MI bleeding and premature P2Y12 inhibitor therapy cessation among these patients.
Study authors reported that sacubitril/valsartan was effective in both ischemic and non-ischemic cardiomyopathy, including the major subgroups of non-ischemic etiology.
Extended use of betrixaban beyond the usual period of parenteral prophylaxis with enoxaparin reduced venous thromboembolism (VTE) incidence among medically ill patients.
Researchers aimed to compare the efficacy of sotalol to other drugs used to prevent arrhythmias (eg, beta-blockers, amiodarone).
Risk reductions in composite outcomes of hospitalization for heart failure (HHF) and modes of cardiovascular (CV) death observed with empagliflozin were comparable to the reduction in the pre-specified composite of HHF or CV death in the EMPAG-REG OTUCOME trial
The efficacy of folic acid supplementation on the risk of stroke was greatest in the lowest quartile of platelet count among hypertensive adults.
Study data found vitamin D to be an important risk factor for acute coronary syndrome (ACS) and severe coronary artery disease (CAD).
Prophylactic IV amiodarone lowered the incidence of atrial fibrillation (AF) after esophagectomy but was associated with several adverse effects post-esophagectomy.
Among eligible patients with heart failure and reduced ejection fraction (HFrEF), use of spironolactone was associated with improved clinical outcomes.
The safety and efficacy of cangrelor was studied in a subgroup of patients taking unfractionated heparin for PCI in the modified intent-to-treat (mITT) population of the CHAMPION PHOENIX trial.
The network meta-analysis to compare the effects on CV outcomes among 3 major antidiabetic drug classes: DPP-4 inhibitors, GLP-1 receptor agonists, and SGLT-2 inhibitors.
Clinicians who treat patients with heart disease should be aware of the increased risk of fractures and screen for bone disease in this patient population.
Patients were current statin users and had an LDL-C ≥70mg/dL, they were considered to have reached goal if they achieved an LDL-C level of less than 70mg/dL after 3 months of ezetimibe treatment.
While considered a standard treatment for atherosclerotic cardiovascular disease, the benefits of statins in patients with vasospastic angina were still an unknown.
At baseline, among 9722 patients with AF, frailty (defined by the American Geriatric Society Criteria) was identified in 5.9% of patients.
The researchers searched the U.S. Medicare database for NVAF patients 65 years of age and older who were newly prescribed one of the following medications: apixaban, dabigatran, rivaroxaban, or warfarin.
Study authors aimed to evaluate the association between beta-blocker use and all-cause mortality in patients presenting with ACS based on the presence or absence of significant LV dysfunction.
The patient was brought to the emergency department (ED) after complaining of abdominal and chest pain that came on suddenly without exertion.