AACE 2017

Antithyroid Drug Induces Rare, Dangerous Side Effect

By May 11, 2017

"Periodic screening and monitoring of CBC while on treatment is crucial to monitor development of neutropenia which can be totally asymptomatic," the authors concluded.

Hyperglycemia Despite High Doses of IV Insulin: An Administration Error?

By May 09, 2017

An interaction check showed that norepinephrine is not compatible with insulin in the same line as it renders the insulin ineffective.

Hypoglycemia Rate, A1c Goals Compared for Basal Insulin Switches

By May 06, 2017

Switching basal insulins to GLA-300 vs. other basal insulins showed similarly improved glycemic cotrol but with significantly lower risk of hypoglycemia.

Switching to Insulin Glargine U300 Beneficial in Poorly Controlled Diabetes

By May 06, 2017

Study patients showed reduced HbA1c and pre-prandial insulin requirements after transitioning to insulin glargine U300.

ALT, AST Changes Linked to Glucose Parameters Changes in Tesamorelin-Treated Patients

By May 06, 2017

Tesamorelin is a synthetic analogue of human growth hormone-releasing hormone.

Significant Improvement in Glycemic Control With Weight Loss Intervention

By May 06, 2017

A retrospective study to assess phentermine and the OPTIFAST diet program on weight and diabetes outcomes at 6 months.

How Does Highly Active Antiretroviral Therapy Impact BMI in HIV Patients?

By May 06, 2017

Findings from this review were consistent with other short-term studies that evaluated weight changes post-HAART initiation.

Weekly vs. Daily Levothyroxine for Hypothyroidism: What's More Effective?

By May 06, 2017

Once-weekly levothyroxine vs. daily levothyroxine proved safe and effective for the treatment of hypothyroidism in non-adherent young and middle-aged adults.

Brand vs. Generic Levothyroxine: Effect on TSH Lab Data Compared

By May 06, 2017

Synthroid was associated with an 11% lower likelihood of having TSH labs out of range when compared with similar patients taking generic levothyroxine.

Effect of Vit D Replacement in Patients With Subclinical Hypothyroidism

By May 06, 2017

After 3 months of treatment with vitamin D, the researchers found a significant increase in serum vitamin D as well as significant reductions in TSH to 4.7 and anti TPO titre.

Real-World Weight Loss Effect of Phentermine Examined

By May 05, 2017

Among the responders, the overall reduction in body weight was 7.2kg with a fall in systolic blood pressure of 3.4mmHg.

Does Somatotropin Impact Lipid Levels in Growth Hormone Deficient Adults?

By May 05, 2017

Somatotropin (recombinant human growth hormone) in adults with growth hormone deficiency significantly raised HDL levels at 24 months.

Liraglutide Examined for Efficacy in Type 1 Diabetes

By May 05, 2017

A group of 26 patients with uncontrolled type 1 diabetes were randomly divided to either 1.8mg of liraglutide or placebo after fasting overnight.

Canagliflozin May Improve Cardiometabolic Health in T2DM Patients

By May 05, 2017

Data results found that treatment with canagliflozin decreased serum levels of leptin and IL-6 compared to GLIM (26% reduction for leptin, 23% reduction for IL-6).

Lower GI Events With Insulin Glargine + Lixisenatide vs. Lixisenatide Alone

By May 05, 2017

Treatment with iGlarLixi resulted in a lower rate of gastrointestinal (GI) adverse events vs. Lixi, according to findings from a post-hoc analysis.

Topical Testosterone Tx Adherence Examined in Hypogonadal Men

By May 05, 2017

The study evaluated adherence to topical testosterone therapy in a real-world cohort of commercially insured males with primary or secondary hypogonadism.

Parenteral Nutrition May Up In-Hospital Stay, Mortality in CHF Patients

By May 05, 2017

The presence of comorbid CHF was also related to a higher rate of ICU admission.

Canagliflozin vs. Sitagliptin: Real-World Weight Loss, Glycemic Control Analysis

By May 05, 2017

The analysis showed mean HbA1c was reduced in both treatment arms but was significantly lower in the canagliflozin arm vs. sitagliptin arm.

Case: Serious Adverse Event With Testosterone Use in Healthy Male

By May 05, 2017

The 28-year-old male patient presented with acute-onset vertigo, nausea, vomiting, and unsteady gait.

SGLT2i vs. GLP-1 Agonist: Treatment Progression, Persistence Compared

By May 05, 2017

Results of the study found that the time to obtain an HbA1c <8% was similar for the CANA and GLP-1 agonist groups.

Single-Pill vs. Monotherapy in Achieving, Maintaining HbA1c Goal Compared

By May 05, 2017

Results of this analysis found that patients treated with empagliflozin/linagliptin single-pill combination were more likely to reach and maintain an HbA1c target of ≤7% compared to patients treated with monotherapy.

Improving Glucose Control By Analyzing Insulin Injection Technique

By May 04, 2017

This study describes three cases in which patients experienced hyperglycemia despite dose titration due to incorrect injection.

Case: Dietary Supplement Use Leads to Thyroid Disease

By May 04, 2017

The case involves a 39-year old male patient who stated that he had an intentional 10-pound weight loss over a 2-month period after starting a dietary supplement that was a "fad" at his office.

A Novel Approach to Delivering Basal-Prandial Insulin

By May 04, 2017

A significant reduction was seen in the total daily dose for V-Go patients who had been previously administering ≥2 insulin injections per day.

Does Low Testosterone Up Anemia Risk in Patients With Type 2 Diabetes?

By May 04, 2017

In type 2 diabetic male patients, a low testosterone level was found to be associated with anemia. These findings are consistent with previous reports.

Liraglutide Reduces HbA1C, Body Weight in Type 1 Diabetes

By May 04, 2017

The study aimed at analyzing data obtained from randomized controlled trials (RCTs) to determine the safety and efficacy of glucagon like peptide-1 receptor agonists (GLP-1RA) in patients with T1DM.

Early Initiation of Insulin Shows Long-Term Benefit in Type 2 Diabetes

By May 04, 2017

This retrospective analysis demonstrated that early initiation of insulin is beneficial in patients with new onset T2DM.

Complete Remission Seen With GLP-1 Agonist Therapy in T2DM Patients

By May 04, 2017

The study authors reported that treatment with LIRA significantly improved all clinical parameters tested for patients with new onset T2DM.

Case Investigates Prolonged Hypocalcemia Induced by Denosumab

By May 04, 2017

When intravenous boluses of calcium gluconate failed to improve the patient's serum calcium levels, he was initiated on a continuous calcium gluconate infusion over 36 hours.

Topical Steroid Use in Psoriasis Patient Leads to Severe Adrenal Insufficiency

By May 04, 2017

Upon presentation to the endocrine clinic for evaluation of his low serum cortisol, the patient complained of a 24-pound weight gain over a two-year period, feeling fatigued, as well as facial puffiness.